217 Result(s)

Article

Correction to: AHA Life’s Essential 8 and new‑onset CKD: a prospective cohort study from the UK Biobank

Yong-**ang Ruan, Mao-**ong Wu, **g-Wei Gao… in Clinical and Experimental Nephrology (2024)

Article

PANX1-mediated ATP release confers FAM3A’s suppression effects on hepatic gluconeogenesis and lipogenesis

Extracellular adenosine triphosphate (ATP) is an important signal molecule. In previous studies, intensive research had revealed the crucial roles of family with sequence similarity 3 member A (FAM3A) in contr...

Cheng-Qing Hu, Tao Hou, Rui **ang, **n Li, **g Li… in Military Medical Research (2024)

Article

Accurate and affordable detection of rifampicin and isoniazid resistance in Tuberculosis sputum specimens by multiplex PCR-multiple probes melting analysis

Escalating cases of multidrug-resistant tuberculosis (MDR-TB) pose a major challenge to global TB control efforts, necessitating innovative diagnostics to empower decentralized detection of gene mutations asso...

Long **e, **ao-Ya Zhu, Li Xu, **ao-**e Xu, Ze-Fan Ruan, Ming-**ang Huang… in Infection (2024)

Article

A simplified herbal decoction attenuates myocardial infarction by regulating macrophage metabolic reprogramming and phenotypic differentiation via modulation of the HIF-1α/PDK1 axis

Myocardial infarction (MI) poses a global public health challenge, often associated with elevated mortality rates and a grim prognosis. A crucial aspect of the inflammatory injury and healing process post-MI i...

Zhi-jun Lin, **n Dong, Huan He, Jia-lin Jiang, Zhuo-ji Guan, Xuan Li… in Chinese Medicine (2024)

Article

Detection and diagnosis of automated breast ultrasound in patients with BI-RADS category 4 microcalcifications: a retrospective study

Automated Breast Ultrasound (AB US) has shown good application value and prospects in breast disease screening and diagnosis. The aim of the study was to explore the ability of AB US to detect and diagnose mam...

Li-Fang Yu, Chao-Chao Dai, Luo-** Zhu, **ao-**g Xu, Hong-Ju Yan… in BMC Medical Imaging (2024)

Article

The safety and short-term effect of mixed approach in laparoscopic right hemicolectomy for right colon cancer compared with middle approach: a retrospective study

To investigate whether the mixed approach is a safe and advantageous way to operate laparoscopic right hemicolectomy.

Shun-Yu Deng, Mao-**ng Liu, Pin Gao, Cheng-cai Zhang, Jia-Di **ng… in BMC Surgery (2024)

Article

Oral arsenic plus imatinib versus imatinib solely for newly diagnosed chronic myeloid leukemia: a randomized phase 3 trial with 5-year outcomes

The synergistic effects of combining arsenic compounds with imatinib against chronic myeloid leukemia (CML) have been established using in vitro data. We conducted a clinical trial to compare the efficacy of t...

Jie Tian, Yong-** Song, Gao-Chong Zhang… in Journal of Cancer Research and Clinical On… (2024)

Article

Renal interstitial fibrotic assessment using non-Gaussian diffusion kurtosis imaging in a rat model of hyperuricemia

To investigate the feasibility of Diffusion Kurtosis Imaging (DKI) in assessing renal interstitial fibrosis induced by hyperuricemia.

**-Kang Chen, Zhong-Yuan Cheng, Ya-Lin Wang, Bao-Jun Xu… in BMC Medical Imaging (2024)

Article

MicroRNA-377-3p exacerbates chronic obstructive pulmonary disease through suppressing ZFP36L1 expression and inducing lung fibroblast senescence

Chronic obstructive pulmonary disease (COPD) is a leading aging related cause of global mortality. Small airway narrowing is recognized as an early and significant factor for COPD development. Senescent fibrob...

Fang Lu, Li-peng Yao, Dan-dan Gao, Tahereh Alinejad, **n-qing Jiang… in Respiratory Research (2024)

Article

Novel beagle model of gastric local fibrotic target lesions for the evaluation and training of endoscopic techniques

Novel endoscopic techniques used in the treatment of gastric lesions with local submucosal fibrosis need preclinical evaluation and training due to safety limitations. Therefore, the purpose of our study was t...

**ao-Jian He, **ao-Ling Wang, Chuan-Shen Jiang, Dong-Gui Hong… in BMC Gastroenterology (2023)

Article

Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways

G-protein coupled receptors (GPCRs) are recognized as attractive targets for drug therapy. However, it remains poorly understood how GPCRs, except for a few chemokine receptors, regulate the progression of liv...

Kun Zhang, Meng-**a Zhang, **ao-**ang Meng, **g Zhu… in Military Medical Research (2023)

Article

Metatranscriptome of human lung microbial communities in a cohort of mechanically ventilated COVID-19 Omicron patients

The Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infected a substantial proportion of Chinese population, and understanding the factors underlying the severity of the dis...

Lin Wang, Jia-Bao Cao, Bin-Bin **a, Yue-Juan Li… in Signal Transduction and Targeted Therapy (2023)

Article

Analysis and validation of diagnostic biomarkers and immune cell infiltration characteristics in pediatric sepsis by integrating bioinformatics and machine learning

Pediatric sepsis is a complicated condition characterized by life-threatening organ failure resulting from a dysregulated host response to infection in children. It is associated with high rates of morbidity a...

Wen-Yuan Zhang, Zhong-Hua Chen, **ao-**a An, Hui Li… in World Journal of Pediatrics (2023)