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  1. Article

    Open Access

    Dysfunction of duplicated pair rice histone acetyltransferases causes segregation distortion and an interspecific reproductive barrier

    Postzygotic reproductive isolation, which results in the irreversible divergence of species, is commonly accompanied by hybrid sterility, necrosis/weakness, or lethality in the F1 or other offspring generations. ...

    Ben Liao, You-Huang **ang, Yan Li, Kai-Yang Yang, Jun-**ang Shan in Nature Communications (2024)

  2. Article

    Open Access

    RNA sequencing and proteomic profiling reveal alterations by MPTP in chronic stomach mucosal injury in tree shrew Chinese (Tupaia belangeri chinensis)

    1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a neurotoxin that can cause gastrointestinal ulcers by affecting dopamine levels. Therefore, MPTP has been considered a toxic substance that causes gastri...

    Chen-yun Wang, You-song Ye, Wei-hu Long, Zhe-li Li, Hong Zheng in Scientific Reports (2024)

  3. Article

    Open Access

    A saturated map of common genetic variants associated with human height

    Common single-nucleotide polymorphisms (SNPs) are predicted to collectively explain 40–50% of phenotypic variation in human height, but identifying the specific variants and associated regions requires huge sa...

    Loïc Yengo, Sailaja Vedantam, Eirini Marouli, Julia Sidorenko, Eric Bartell in Nature (2022)

  4. Article

    Open Access

    Large-scale and high-resolution mass spectrometry-based proteomics profiling defines molecular subtypes of esophageal cancer for therapeutic targeting

    Esophageal cancer (EC) is a type of aggressive cancer without clinically relevant molecular subtypes, hindering the development of effective strategies for treatment. To define molecular subtypes of EC, we per...

    Wei Liu, Lei **e, Yao-Hui He, Zhi-Yong Wu, Lu-**n Liu in Nature Communications (2021)

  5. Article

    Open Access

    Cardiometabolic diseases, frailty, and healthcare utilization and expenditure in community-dwelling Chinese older adults

    This study investigated associations between cardiometabolic diseases, frailty, and healthcare utilization and expenditure among Chinese older adults. The participants were 5204 community-dwelling adults aged ...

    Ke Gao, Bo-Lin Li, Lei Yang, Dan Zhou, Kang-** Ding, Ju Yan in Scientific Reports (2021)

  6. Article

    Addendum: A pneumonia outbreak associated with a new coronavirus of probable bat origin

    Peng Zhou, **ng-Lou Yang, **an-Guang Wang, Ben Hu, Lei Zhang, Wei Zhang in Nature (2020)

  7. Article

    Open Access

    Author Correction: Repair of bone defects with prefabricated vascularized bone grafts and double-labeled bone marrow-derived mesenchymal stem cells in a rat model

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    **ao-Rui Jiang, Hui-Ying Yang, **n-**n Zhang, Guo-Dong Lin in Scientific Reports (2020)

  8. Article

    Open Access

    A pneumonia outbreak associated with a new coronavirus of probable bat origin

    Since the outbreak of severe acute respiratory syndrome (SARS) 18 years ago, a large number of SARS-related coronaviruses (SARSr-CoVs) have been discovered in their natural reservoir host, bats14. Previous studi...

    Peng Zhou, **ng-Lou Yang, **an-Guang Wang, Ben Hu, Lei Zhang, Wei Zhang in Nature (2020)

  9. Article

    Open Access

    VHL deficiency augments anthracycline sensitivity of clear cell renal cell carcinomas by down-regulating ALDH2

    The von Hippel-Lindau (VHL) is deficient in ∼70% of clear-cell renal cell carcinomas (ccRCC), which contributes to the carcinogenesis and drug resistance of ccRCC. Here we show that VHL-deficient ccRCC cells p...

    Yao-Hui Gao, Zhao-**a Wu, Li-Qi **e, Cai-**a Li, Yu-Qin Mao in Nature Communications (2017)

  10. Article

    Open Access

    Repair of bone defects with prefabricated vascularized bone grafts and double-labeled bone marrow-derived mesenchymal stem cells in a rat model

    This study aims to investigate the repair of bone defects with prefabricated vascularized bone grafts and double-labeled bone marrow-derived mesenchymal stem cells (BMSCs) in a rat model. BMSCs were separated ...

    **ao-Rui Jiang, Hui-Ying Yang, **n-**n Zhang, Guo-Dong Lin in Scientific Reports (2017)

  11. No Access

    Article

    Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis

    The role of the unfolded protein response (UPR) in tissue homeostasis remains largely unknown. Here we find that loss of Mst1/2, the mammalian Hippo orthologues, or their regulator WW45, leads to a remarkably ...

    Hongtan Wu, Luyao Wei, Fuqin Fan, Suyuan Ji, Shihao Zhang in Nature Communications (2015)