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    The checkpoint 1 kinase inhibitor LY2603618 induces cell cycle arrest, DNA damage response and autophagy in cancer cells

    Chemotherapy- or radiotherapy-induced DNA damage activates the Chk1-dependent DNA damage response (DDR) and cell cycle checkpoints to facilitate cell survival. Numerous attempts have been made to identify spec...

    Feng-Ze Wang, Hong-rong Fei, Ying-Jie Cui, Ying-Kun Sun, Zhao-Mei Li… in Apoptosis (2014)