Skip to main content

and
  1. Article

    Open Access

    The causal relationship between white blood cell counts and hepatocellular carcinoma: a Mendelian randomization study

    Most of hepatocellular carcinoma (HCC) arises on the background of chronic inflammation. The presence of infiltrating inflammatory cells is associated with tumour initiation, progression and clinical response ...

    Guo-Qiang Pan, Chun-Cheng Yang, **ao-ling Shang in European Journal of Medical Research (2022)

  2. No Access

    Article

    Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter

    Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter.

    **g Wang, Chongxiu Sun, Norbert Gerdes, Conglin Liu, Mengyang Liao in Nature Medicine (2015)

  3. No Access

    Article

    A delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapy

    Zhang and colleagues have developed a new targeted delivery system for RNA interference–based bone anabolic therapy. Using dioleoyl trimethylammonium propane (DOTAP)-based cationic liposomes attached to six re...

    Ge Zhang, Baosheng Guo, Heng Wu, Tao Tang, Bao-Ting Zhang, Lizhen Zheng in Nature Medicine (2012)

  4. No Access

    Article

    The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension

    Calcineurin inhibitors, such as tacrolimus, are widely used immunosuppressive agents, but they can cause hypertension. In studies of tacrolimus-treated mice, the authors show that hypertension is due to activa...

    Ewout J Hoorn, Stephen B Walsh, James A McCormick, Antje Fürstenberg in Nature Medicine (2011)