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Inhibition of PPP1R15A alleviates osteoporosis via suppressing RANKL-induced osteoclastogenesis

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  1. Article

    Open Access

    Hemothorax caused by injury of musculophrenic artery after ultrasound-guided percutaneous liver biopsy: a case report

    Hemorrhage is the most common major complication after liver biopsy. Hemothorax is one type of bleeding and is very rare and dangerous. Several cases of hemothorax subsequent to liver biopsy have been document...

    **g-ru Yang, Sai Wu, Jian Li, **ao-juan Tian in Journal of Medical Case Reports (2024)

  2. Article

    Open Access

    The correlation between lung ultrasound scores and outcomes of high-flow nasal cannula therapy in infants with severe pneumonia

    The study aimed to explore the effectiveness of bedside lung ultrasound (LUS) combined with the PaO2/FiO2 (P/F) ratio in evaluating the outcomes of high-flow nasal cannula (HFNC) therapy in infants with severe pn...

    Li-Ling Zheng, Rou Chen, Chan-Hua Zheng, **ao-Juan Dai, Wei-Da Zheng in BMC Pediatrics (2024)

  3. Article

    Author Correction: Pharmacokinetics, mass balance, and metabolism of [14C]vicagrel, a novel irreversible P2Y12 inhibitor in humans

    Yuan-dong Zheng, Hua Zhang, Yan Zhan, Yi-cong Bian, Sheng Ma in Acta Pharmacologica Sinica (2023)

  4. Article

    Open Access

    Anti-complement factor H (CFH) autoantibodies could delay pristane-induced lupus nephritis

    Anti-complement factor H (CFH) autoantibodies could be detected in lupus and its significance remained to be elucidated. Herein, we aimed to explore the roles of anti-CFH autoantibodies based on pristane-induc...

    Lin-Lin Li, Zhong-qiu Luan, Ying Tan, Hui Wang, **ao-Juan Yu in Immunologic Research (2023)

  5. Article

    Open Access

    Inhibition of USP1 reverses the chemotherapy resistance through destabilization of MAX in the relapsed/refractory B-cell lymphoma

    The patients with relapsed and refractory diffuse large B-cell lymphoma (DLBCL) have poor prognosis, and a novel and effective therapeutic strategy for these patients is urgently needed. Although ubiquitin-spe...

    **-Ya Li, Ji-Chuan Wu, ** Liu, Zi-Juan Li, Yong Wang, Bing-Yi Chen in Leukemia (2023)

  6. Article

    Open Access

    Sulfated alginate oligosaccharide exerts antitumor activity and autophagy induction by inactivating MEK1/ERK/mTOR signaling in a KSR1-dependent manner in osteosarcoma

    Alginate oligosaccharide (AOS) has the function to inhibit tumor progression and the sulfated modification can enhance the antitumor activity. To date, the function and mechanism of sulfated AOS (AOS-SO4) in tumo...

    Zhen Pan, **ao-juan Wei, Shi-jie Li, Hua Guo, Zhao-hui Li, Ke-ke Zhang in Oncogenesis (2022)

  7. Article

    Open Access

    An update of the long-term outcome of patients with nonspecific pleurisy at medical thoracoscopy

    Medical thoracoscopy (MT) is recommended in patients with undiagnosed exudative pleural effusion and offers a degree of diagnostic sensitivity for pleural malignancy. However, not all patients who undergo MT r...

    Yan-**a Yu, Yuan Yang, Yan-Bing Wu, **ao-Juan Wang, Li-Li Xu in BMC Pulmonary Medicine (2021)

  8. Article

    Open Access

    Reprogramming immunosuppressive myeloid cells by activated T cells promotes the response to anti-PD-1 therapy in colorectal cancer

    Overcoming local immunosuppression is critical for immunotherapy to produce robust anti-tumor responses. Myeloid-derived suppressor cells (MDSCs) are key regulators of immunosuppressive networks and promote tu...

    **g Chen, Hong-Wei Sun, Yan-Yan Yang in Signal Transduction and Targeted Therapy (2021)

  9. Article

    Open Access

    Poor cardiovascular health status among Chinese women

    Systematic investigation and analysis of cardiovascular health status (CVHS) of Chinese women is rare. This study aimed to assess CVHS and atherosclerotic cardiovascular disease (ASCVD) burden in the Chinese w...

    Tian-Wen Han, Yu-Qi Liu, Wei Dong, **ao-Juan Bai in BMC Cardiovascular Disorders (2020)

  10. Article

    Open Access

    Clinical and pathological findings of SARS-CoV-2 infection and concurrent IgA nephropathy: a case report

    Since the Coronavirus Disease 2019 (COVID-19) outbreak, there is accumulating data on the clinical characteristics, treatment strategies and prognosis of COVID-19 in patients with concurrent renal disease. Pos...

    Yi Huang, **ao-Juan Li, Yue-Qiang Li, Wei Dai, Tiffany Shao, Wei-Yong Liu in BMC Nephrology (2020)

  11. Article

    First case of COVID-19 complicated with fulminant myocarditis: a case report and insights

    Coronavirus disease 2019 (COVID-19) has been demonstrated to be the cause of pneumonia. Nevertheless, it has not been reported as the cause of acute myocarditis or fulminant myocarditis.

    Jia-Hui Zeng, Ying-**a Liu, **g Yuan, Fu-**ang Wang, Wei-Bo Wu, **-**u Li in Infection (2020)

  12. Article

    Open Access

    Ty** of hereditary renal amyloidosis presenting with isolated glomerular amyloid deposition

    The commonly used methods for amyloid ty** include immunofluorescence or immunohistochemistry (IHC), which sometimes may come with diagnostic pitfalls. Mass spectrometry (MS)-based proteomics has been recogn...

    Danyang Li, Dan Liu, Hui Xu, **ao-juan Yu, Fu-de Zhou, Ming-hui Zhao in BMC Nephrology (2019)

  13. Article

    Open Access

    Canscora lucidissima, a Chinese folk medicine, exerts anti-inflammatory activities by inhibiting the phosphorylation of ERK1/2 in LPS-activated macrophages

    Canscora lucidissima (Levl. & Vaniot) Hand.-Mazz. (C. lucidissima), mainly distributed in southern China, has been shown to be effective in the treatment of inflammatory diseases. However, the underlying mechanis...

    Qiao-ling Fei, **ao-yu Zhang, Rui-juan Qi in BMC Complementary and Alternative Medicine (2019)

  14. Article

    Open Access

    Monoclonal immunoglobulin mediates complement activation in monoclonal gammopathy associated-C3 glomerulonephritis

    C3 glomerulonephritis (C3GN) is a rare disease caused by inherited or acquired complement alternative pathway (CAP) dysregulation, which could also be secondary to monoclonal gammopathy of undetermined signifi...

    Lin-Lin Li, Zhi-Ying Li, Su-**a Wang, **ao-Juan Yu, Ying Tan, Yu Wang in BMC Nephrology (2019)

  15. Article

    Open Access

    Total saponins of Bolbostemma paniculatum (maxim.) Franquet exert antitumor activity against MDA-MB-231 human breast cancer cells via inhibiting PI3K/Akt/mTOR pathway

    The aim of the present study was to examine the effects of the Bolbostemma paniculatum (Maxim.) Franquet (BP) active compound, BP total saponins (BPTS), on MDA-MB-231 cells, and investigate the underlying mechani...

    Jian-Wei Dou, Rong-Guo Shang, **ao-Qin Lei in BMC Complementary and Alternative Medicine (2019)

  16. Article

    Open Access

    **aoyaosan exerts antidepressant-like effects by regulating the functions of astrocytes and EAATs in the prefrontal cortex of mice

    Mounting evidence indicates that the cerebral cortex is an important physiological system of emotional activity, and its dysfunction may be the main cause of stress. Glutamate is the primary excitatory neurotr...

    Yan Liu, **u-fang Ding, **n-xing Wang in BMC Complementary and Alternative Medicine (2019)

  17. Article

    Open Access

    Improved heart hemodynamics after draining large-volume pleural effusion: a prospective cohort study

    Pleural effusion (PE) drainage can relieve the symptoms of dyspnea; however, details of the resulting hemodynamic changes remain undefined.

    Zheng Wang, Qi-Zhe Cai, Cheng-Jun Ban, Duo Chen, Li-Li Xu in BMC Pulmonary Medicine (2018)

  18. Article

    Open Access

    Malignant pleural mesothelioma: diagnostic value of medical thoracoscopy and long-term prognostic analysis

    Malignant pleural mesothelioma (MPM) is marked by its difficult diagnosis and poor prognosis. Medical thoracoscopy (MT) is an effective and safe procedure for the diagnosis of exudative pleural effusions and m...

    Li-Li Xu, Yuan Yang, Zhen Wang, **ao-Juan Wang, Zhao-Hui Tong in BMC Pulmonary Medicine (2018)

  19. Article

    Open Access

    Diagnostic value of medical thoracoscopy in malignant pleural effusion

    Medical thoracoscopy has been shown to be an efficacious procedure in diagnosing unexplained exudative pleural effusions with excellent safety. This study aimed to assess the diagnostic significance of thoraco...

    Yan-Bing Wu, Li-Li Xu, **ao-Juan Wang, Zhen Wang, Jun Zhang in BMC Pulmonary Medicine (2017)

  20. Article

    Effects of gene polymorphisms in the endoplasmic reticulum stress pathway on clinical outcomes of chemoradiotherapy in Chinese patients with nasopharyngeal carcinoma

    There is considerable inter-individual variabil¬ity in chemoradiotherapy responses in nasopharyngeal carcinoma (NPC) patients receiv¬ing the same or similar treatment protocols. In this study we evaluated the ...

    **ao-bin Guo, Wan-le Ma, Li-juan Liu, Yu-ling Huang in Acta Pharmacologica Sinica (2017)

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