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Article
Open AccessThe efficacy and safety of dalpiciclib, a cyclin-dependent kinase 4/6 inhibitor, in patients with advanced head and neck mucosal melanoma harboring CDK4 amplification
Mucosal melanoma (MM) is a rare but devastating subtype of melanoma. Our previous studies have demonstrated robust anti-tumor effects of cyclin-dependent kinase 4/6 (CDK 4/6) inhibitors in head and neck MM (HN...
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Article
Open AccessPotential role of cyclin-dependent kinase 4/6 inhibitors in the treatment of mucosal melanoma
Mucosal melanoma (MM) is a rare and aggressive form of melanoma with a poorer prognosis compared to other subtypes. Recent large-scale next-generation sequencing studies, including our own research, have demon...
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Article
Open AccessImmune persistence after different polio sequential immunization schedules in Chinese infants
Trivalent oral poliovirus vaccine (tOPV) has been withdrawn and instead an inactivated poliovirus vaccine (IPV) and bivalent type 1 and type 3 OPV (bOPV) sequential immunization schedule has been implemented s...
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Article
Mechanically flexible V3S4@carbon composite fiber as a high-capacity and fast-charging anode for sodium-ion capacitors
Hybrid Na-ion capacitors (NICs) have received considerable interests owing to their low-cost, high-safety, and rapidly charging energy-storage characteristics. The NICs are composed of a capacitor-type cathode...
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Article
Open AccessEvaluation of the immunization effectiveness of bOPV booster immunization and IPV revaccination
To provide a basis for further optimization of the polio sequential immunization schedule, this study evaluated the effectiveness of booster immunization with one dose of bivalent oral poliovirus vaccine (bOPV...
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Chapter and Conference Paper
Study on Technical Limits of Commingling Production in Deep Gas Reservoirs with Water
As for commingling gas reservoirs with water, the reasonable development has always been a difficult problem. Moreover, this becomes the especially big problem in deep acidic gas reservoirs to improve the deve...
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Article
Brand Identification of Soybean Milk Powder based on Raman Spectroscopy Combined with Random Forest Algorithm
Raman spectroscopy can characterize the rich molecular vibration information of soybean milk powder samples, but difficulties arise in its direct use for sample classification and identification. Therefore, it...
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Article
Dysregulation of iron homeostasis and methamphetamine reward behaviors in Clk1-deficient mice
Chronic administration of methamphetamine (METH) leads to physical and psychological dependence. It is generally accepted that METH exerts rewarding effects via competitive inhibition of the dopamine transport...
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Article
Open AccessCorrelation of serum N-Acetylneuraminic acid with the risk and prognosis of acute coronary syndrome: a prospective cohort study
N-acetylneuraminic acid (Neu5Ac) is a functional metabolite involved in coronary artery disease (CAD). We aimed to evaluate the relationship between serum Neu5Ac and the risk and prognosis of acute coronary sy...
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Article
Open AccessChemoprophylaxis, diagnosis, treatments, and discharge management of COVID-19: An evidence-based clinical practice guideline (updated version)
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness, coronavirus disease 2019 (COVID-19), affecting more than seventeen million people around the ...
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Article
Development of a loop-mediated isothermal amplification (LAMP) assay for rapid detection of Pseudomonas syringae pv. tomato in planta
Tomato bacterial speck, caused by Pseudomonas syringae pv. tomato (Pst), is one of the most devastating bacterial diseases in tomato worldwide. To establish a rapid amplification system for the detection of Pst, ...
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Article
Coupling effect and characterization modeling of iron ore fines mixing and granulating at 0–1 mm
Characteristic of iron ore is the essential factor of granulating. Three ores, namely specularite, magnetite concentrate and limonite, were selected as adhesion powder to investigate granulating behavior and e...
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Article
Open AccessImpact of combined ischemic preconditioning and remote ischemic perconditioning on ischemia-reperfusion injury after liver transplantation
Ischemic preconditioning (IPC) and remote ischemic perconditioning (RIPer) confer protective effects against liver ischemia-reperfusion injury (IRI), but data about RIPer applying in liver transplantation is l...
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Article
Low operating temperature CO sensor prepared using SnO2 nanoparticles
A low operating temperature CO (carbon monoxide) sensor was fabricated from a nanometer-scale SnO2 (tin oxide) powder. The SnO2 nanoparticles in a size range 10–20 nm were synthesized as a function of surfactant ...
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Article
Association of reduced sclerostin expression with collapse process in patients with osteonecrosis of the femoral head
Sclerostin is an osteocyte-derived protein that has a potent inhibitory effect on osteoblast activity. The osteocyte apoptosis induced by various causes of osteonecrosis of the femoral head (ONFH) plays a key ...
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Article
Effect of Kuanxiong Aerosol (宽胸气雾剂) on Patients with Angina Pectoris: A Non-inferiority Multi-center Randomized Controlled Trial
To evaluate the effect and safety of Kuanxiong Aerosol (宽胸气雾剂, KA) on patients with angina pectoris.
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Article
Pyrimethanil sensitivity and fitness in Botrytis cinerea populations from Shanxi Province, China
Pyrimethanil is a fungicide that is highly active against the plant pathogen Botrytis cinerea. The sensitivity of B. cinerea to pyrimethanil and the risk of resistance were investigated in Shanxi, China. A total...
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Article
Open Access31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one
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Article
Open AccessMicrowave assisted synthesis, antifungal activity, DFT and SAR study of 1,2,4-triazolo[4,3-a]pyridine derivatives containing hydrazone moieties
The increasing prevalence of multi-drug resistant fungal infections has encouraged the search for new antifungal agents. Hydrazone derivatives always exhibited diversity activities, including antifungal, anti-...
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Article
Prognostic significance of parameters from pretreatment 18F-FDG PET in hepatocellular carcinoma: a meta-analysis
The prognostic value of 18F-deoxyglucose positron emission tomography (18F-FDG PET) on hepatocellular carcinoma (HCC) remains inconclusive. This study aims to investigate the prognostic role of pretreatment 18F-F...
