1,161 Result(s)
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Article
Open AccessA novel technique for the single-port laparoscopic percutaneous extraperitoneal closure (SLPEC) of paediatric isolated giant inguinal hernias using double-modified hernia needles
The objective was to explore the efficacy of single-port laparoscopic percutaneous extraperitoneal closure using double-modified hernia needles with hydrodissection (SLPEC group) and two-port laparoscopic perc...
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Article
Benefits of Hepatitis C Viral Eradication: A Real-World Nationwide Cohort Study in Taiwan
Chronic hepatitis C (CHC) increases the risk of liver cirrhosis (LC) and hepatocellular carcinoma (HCC). This nationwide cohort study assessed the effectiveness of viral eradication of CHC.
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Transformation of A1/A2 Astrocytes Participates in Brain Ischemic Tolerance Induced by Cerebral Ischemic Preconditioning via Inhibiting NDRG2
Cerebral ischemic preconditioning (CIP) has been shown to improve brain ischemic tolerance against subsequent lethal ischemia. Reactive astrocytes play important roles in cerebral ischemia–reperfusion. Recent ...
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Salvage haploidentical transplantation for graft failure after first haploidentical allogeneic stem cell transplantation: an updated experience
Graft failure is a fatal complication following allogeneic stem cell transplantation where a second transplantation is usually required for salvage. However, there are no recommended regimens for second transp...
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Experimental investigation of vibration pretreatment-microwave curing process for carbon fiber reinforced resin matrix composites
The vibration pretreatment-microwave curing process is an efficient, low energy consumption, and high-quality out-of-autoclave curing process for carbon fiber resin matrix composites. This study aims to invest...
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Open AccessComparative Analysis of Seven Endogenous Hormones in a Novel Dual-axillary Bud Mutant Genotype of Sugarcane
The sugarcane genotype YZ 07-86 is a distinct natural mutant with dual-axillary buds. Exploitation of this valuable trait in sugarcane breeding requires an understanding of the physiological mechanism of dual-...
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Effects of Y on Microstructure and Mechanical Properties of Extruded Mg-5Al-1Ca Magnesium Alloys
The influence of Y content on the microstructure and mechanical properties of the Mg-5Al-1Ca magnesium alloy in the extruded state was investigated. Characterization of the alloy's microstructure was conducted...
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Open AccessWnt5a-mediated autophagy contributes to the epithelial-mesenchymal transition of human bronchial epithelial cells during asthma
The epithelial-mesenchymal transition (EMT) of human bronchial epithelial cells (HBECs) is essential for airway remodeling during asthma. Wnt5a has been implicated in various lung diseases, while its role in t...
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Open AccessLandform and lithospheric development contribute to the assembly of mountain floras in China
Although it is well documented that mountains tend to exhibit high biodiversity, how geological processes affect the assemblage of montane floras is a matter of ongoing research. Here, we explore landform-spec...
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A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease
With the implementation of the 11th edition of the International Classification of Diseases (ICD-11) and the publication of the metabolic dysfunction-associated fatty liver disease (MAFLD) nomenclature in 2020...
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Open AccessREEP3 is a potential diagnostic and prognostic biomarker correlated with immune infiltration in pancreatic cancer
Receptor Expression-Enhancing Protein 3 (REEP3) serves as a pivotal enzyme crucial for endoplasmic reticulum (ER) clearance during mitosis and is implicated in the advancement of diverse malignancies. Nonethel...
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Role and recent progress of P2Y12 receptor in cancer development
P2Y12 receptor (P2Y12R) is an adenosine-activated G protein-coupled receptor (GPCR) that plays a central role in platelet function, hemostasis, and thrombosis. P2Y12R activation can promote platelet aggregatio...
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Open AccessCombined associations of visceral adipose tissue and adherence to a Mediterranean lifestyle with T2D and diabetic microvascular complications among individuals with prediabetes
It’s unclear if excess visceral adipose tissue (VAT) mass in individuals with prediabetes can be countered by adherence to a Mediterranean lifestyle (MEDLIFE). We aimed to examine VAT mass, MEDLIFE adherence, ...
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Open AccessAlternative dimethylsulfoniopropionate biosynthesis enzymes in diverse and abundant microorganisms
Dimethylsulfoniopropionate (DMSP) is an abundant marine organosulfur compound with roles in stress protection, chemotaxis, nutrient and sulfur cycling and climate regulation. Here we report the discovery of a ...
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Bioinformatic Analysis of the Significance of the KIR2DL4 Gene in Recurrent Implantation Failure
Related studies have pointed out that Killer immunoglobulin-like receptor 2DL4 (KIR2DL4) was associated with vascular remodeling in early pregnancy, and it might play an important role in immunity. In this stu...
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T cell-redirecting antibody for treatment of solid tumors via targeting mesothelin
T cell engaging bispecific antibodies (TCBs) have recently become significant in cancer treatment. In this study we developed MSLN490, a novel TCB designed to target mesothelin (MSLN), a glycosylphosphatidylin...
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Retraction Note: Two co(II)-based coordination polymers: photocatalytic dye degradation properties and treatment effect against colon cancer by inhibiting IL-6-STAT3 inflammatory signaling pathway
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Article
Leveraging crystal symmetry for thermoelectric performance optimization in cubic GeSe
In thermoelectrics, the manipulation of crystal symmetry is instrumental in optimizing the electrical and thermal transport parameters. Within this context, the present study explored the largely overlooked hi...
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Article
Lax pair, conservation laws, breather-to-soliton transitions and modulation instability for a coupled extended modified Korteweg-de Vries system in a fluid
The modified Korteweg-de Vries-type equations can be used to describe the interfacial waves in a fluid, elastic quasi-plane waves in a lattice, and Alfvén waves in a collisionless plasma. In this paper, we inv...
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Open AccessEnantioselective synthesis of chiral amides by carbene insertion into amide N–H bond
Chiral amides are important structure in many natural products and pharmaceuticals, yet their efficient synthesis from simple amide feedstock remains challenge due to its weak Lewis basicity. Herein, we descri...