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299 Result(s)
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Article
Laser additive manufacturing of titanium alloys: process, materials and post-processing
Laser additive manufacturing (LAM) of titanium (Ti) alloys has emerged as a transformative technology with vast potential across multiple industries. To recap the state of the art, Ti alloys processed by two e...
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Article
Open AccessGenetic diversity and prevalence of emerging Rickettsiales in Yunnan Province: a large-scale study
Rickettsia and related diseases have been identified as significant global public health threats. This study involved comprehensive field and systematic investigations of various rickettsial organisms in Yunna...
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Article
Regioselective cation exchange reaction for photoelectrochemical water splitting
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Open AccessA deep learning-based algorithm for pulmonary tuberculosis detection in chest radiography
In tuberculosis (TB), chest radiography (CXR) patterns are highly variable, mimicking pneumonia and many other diseases. This study aims to evaluate the efficacy of Google teachable machine, a deep neural netw...
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Article
Vitamin D supplementation for cardiometabolic risk markers in pregnant women based on the gestational diabetes mellitus or obesity status : a randomized clinical trial
Women with gestational diabetes mellitus (GDM) or obesity are vulnerable to impaired gestational cardiovascular health (CVH) and cardiovascular disease (CVD) in the future. It is unclear if prenatal vitamin D ...
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T cell-redirecting antibody for treatment of solid tumors via targeting mesothelin
T cell engaging bispecific antibodies (TCBs) have recently become significant in cancer treatment. In this study we developed MSLN490, a novel TCB designed to target mesothelin (MSLN), a glycosylphosphatidylin...
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Open AccessA multicenter prospective study on the management of hepatoblastoma in children: a report from the Chinese Children’s Cancer Group
This study aimed to identify survival risk factors in Chinese children with hepatoblastoma (HB) and assess the effectiveness of the new treatment protocol proposed by the Chinese Children’s Cancer Group (CCCG)...
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Open AccessThe effect of illness perception on psychosocial adjustment of patients with breast cancer and their spouses: actor–partner independence model
With the increase in the prevalence rate and improvements in the survival of breast cancer patients, there is a growing interest in understanding the level of psychosocial adjustment in these patients. The stu...
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Article
Stepped-up development of accelerator mass spectrometry method for the detection of 60Fe with the HI-13 tandem accelerator
The Moon provides a unique environment for investigating nearby astrophysical events such as supernovae. Lunar samples retain valuable information from these events, via detectable long-lived “fingerprint” rad...
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Article
Robot-assisted versus laparoscopic-assisted gastrectomy among malnourished patients with gastric cancer based on textbook outcome
Textbook outcome (TO) has been widely employed as a comprehensive indicator to assess the short-term prognosis of patients with cancer. Preoperative malnutrition is a potential risk factor for adverse surgical...
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Open AccessDevelopmental characteristics of aggregated lymphoid nodules area in the abomasum of fetal Bactrian camels (Camelus bactrianus)
Bactrian camel is one of the important economic animals in northwest China. They live in arid desert, and their gestation period is about 13 months, which is longer than other ruminants (such as cattle and she...
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Article
Open AccessMNDA expression and its value in differential diagnosis of B-cell non-Hodgkin lymphomas: a comprehensive analysis of a large series of 1293 cases
MNDA (myeloid nuclear differentiation antigen) has been considered as a potential diagnostic marker for marginal zone lymphoma (MZL), but its utility in distinguishing MZL from other B-cell non-Hodgkin lymphom...
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Article
A novel bispecific antibody drug conjugate targeting HER2 and HER3 with potent therapeutic efficacy against breast cancer
Antibody drug conjugate (ADC) therapy has become one of the most promising approaches in cancer immunotherapy. Bispecific targeting could enhance the efficacy and safety of ADC by improving its specificity, af...
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Open AccessSuperoxide dismutases: marker in predicting reduced left ventricular ejection fraction in patients with type 2 diabetes and acute coronary syndrome
To examine the prognostic value of superoxide dismutase (SOD) activity for monitoring reduced left ventricular ejection fraction(LVEF)in the patients with type 2 diabetes and acute coronary syndrome (ACS).
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Article
Surfactant-modified SiO2/FeS nanocomposites for remediation of cadmium pollution
To improve the remediation and antioxygenic properties of ferrous sulfide (FeS) nanomaterials toward heavy metals is the focus of current research. This study employed a combination of sodium carboxymethylcell...
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Open AccessA novel fluffy PLGA/HA composite scaffold for bone defect repair
Treatment of bone defects remains crucial challenge for successful bone healing, which arouses great interests in designing and fabricating ideal biomaterials. In this regard, the present study focuses on deve...
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Preparation of aluminum-tin alloy by electrodeposition in low-temperature molten salt system
AlCl3-NaCl-KCl low-temperature molten salt system with anhydrous SnCl2 was used to study the preparation of Al-Sn alloy by electrodeposition. The morphology and composition of the alloy were analyzed by scanning ...
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Translation, cultural adaptation, and validation of the Chinese standardized outcomes in nephrology–hemodialysis fatigue (C-SONG–HD fatigue) scale: a study of Chinese patients undergoing hemodialysis
This study aimed to translate and culturally adapt the standardized outcomes in nephrology–hemodialysis fatigue (SONG–HD fatigue) scale and to assess the psychometric properties of the Chinese version of the S...
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Article
Open AccessA molecular toolkit of cross-feeding strains for engineering synthetic yeast communities
Engineered microbial consortia often have enhanced system performance and robustness compared with single-strain biomanufacturing production platforms. However, few tools are available for generating co-cultur...
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Article
Open AccessGlobal fungal-host interactome map** identifies host targets of candidalysin
Candidalysin, a cytolytic peptide toxin secreted by the human fungal pathogen Candida albicans, is critical for fungal pathogenesis. Yet, its intracellular targets have not been extensively mapped. Here, we perfo...