28 Result(s)

Article

Development and validation of a neoadjuvant chemotherapy pathological complete remission model based on Reg IV expression in breast cancer tissues: a clinical retrospective study

To develop and authenticate a neoadjuvant chemotherapy (NACT) pathological complete remission (pCR) model based on the expression of Reg IV within breast cancer tissues with the objective to provide clinical g...

Jiao-fei Wei, Fan Li, Jia-wen Lin, Zi-ang Dou, Shu-qin Li, Jun Shen in Breast Cancer (2024)

Article

Comparative analysis of the analgesic effects of intercostal nerve block, ultrasound-guided paravertebral nerve block, and epidural block following single-port thoracoscopic lung surgery

In this study, we compared the analgesic effects of intercostal nerve block (ICNB), ultrasound-guided paravertebral nerve block (PVB), and epidural block (EB) following single-port thoracoscopic lung surgery.

Liang Shen, Zi Ye, Fei Wang, Gao-Feng Sun, Cheng Ji in Journal of Cardiothoracic Surgery (2024)

Article

Cauchy hyper-graph Laplacian nonnegative matrix factorization for single-cell RNA-sequencing data analysis

Many important biological facts have been found as single-cell RNA sequencing (scRNA-seq) technology has advanced. With the use of this technology, it is now possible to investigate the connections among indiv...

Gao-Fei Wang, Longying Shen in BMC Bioinformatics (2024)

Article

Photooxidation triggered ultralong afterglow in carbon nanodots

It remains a challenge to obtain biocompatible afterglow materials with long emission wavelengths, durable lifetimes, and good water solubility. Herein we develop a photooxidation strategy to construct near-in...

Guang-Song Zheng, Cheng-Long Shen, Chun-Yao Niu, Qing Lou… in Nature Communications (2024)

Article

TBK1, a prioritized drug repurposing target for amyotrophic lateral sclerosis: evidence from druggable genome Mendelian randomization and pharmacological verification in vitro

There is a lack of effective therapeutic strategies for amyotrophic lateral sclerosis (ALS); therefore, drug repurposing might provide a rapid approach to meet the urgent need for treatment.

Qing-Qing Duan, Han Wang, Wei-Ming Su, **ao-**g Gu, **ao-Fei Shen… in BMC Medicine (2024)

Article

Radiomic signatures reveal multiscale intratumor heterogeneity associated with tissue tolerance and survival in re-irradiated nasopharyngeal carcinoma: a multicenter study

Post-radiation nasopharyngeal necrosis (PRNN) is a severe adverse event following re-radiotherapy for patients with locally recurrent nasopharyngeal carcinoma (LRNPC) and associated with decreased survival. Bi...

Ting Liu, Di Dong, Xun Zhao, **ao-Min Ou, Jun-Lin Yi, Jian Guan, Ye Zhang… in BMC Medicine (2023)

Article

Camrelizumab combined with apatinib in patients with first-line platinum-resistant or PD-1 inhibitor resistant recurrent/metastatic nasopharyngeal carcinoma: a single-arm, phase 2 trial

Immunotherapy combined with antiangiogenic targeted therapy has improved the treatment of certain solid tumors, but effective regimens remain elusive for refractory recurrent/metastatic nasopharyngeal carcinom...

Li Yuan, Guo-Dong Jia, **ao-Fei Lv, Si-Yi **e, Shan-Shan Guo… in Nature Communications (2023)

Article

Prone position reduces the risk of patients with mild or moderate COVID-19 progressing to severe or even critical cases: a retrospective study

To investigate whether prone position can reduce the risk of patients with mild or moderate COVID-19 who progress to severe or critical illness.

Chuan-cai Xu, Jia-li Xu, **ao-fei Wang, Shen Meng… in European Journal of Medical Research (2022)

Article

Reproductive biology of an endangered lithophytic shrub and implications for its conservation

Plants in cliff habitats may evolve specific reproductive strategies to cope with harsh environments, and unraveling these reproductive characteristics can improve our understanding of survival strategies and ...

Yuan-Mi Wu, Xue-Li Shen, Ling Tong, Feng-Wei Lei, **ao-Fei **a… in BMC Plant Biology (2022)

Article

Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection: a randomized trial

It’s a challenge for detecting the therapeutic targets of a polypharmacological drug from variations in the responsed networks in the differentiated populations with complex diseases, as stable coronary heart ...

Jun Liu, Dan-Dan Li, Wei Dong, Yu-Qi Liu… in Signal Transduction and Targeted Therapy (2021)

Article

Long noncoding RNA BS-DRL1 modulates the DNA damage response and genome stability by interacting with HMGB1 in neurons

Long noncoding RNAs (lncRNAs) are known to regulate DNA damage response (DDR) and genome stability in proliferative cells. However, it remains unknown whether lncRNAs are involved in these vital biological pro...

Min-Min Lou, **ao-Qiang Tang, Guang-Ming Wang, Jia He, Fang Luo… in Nature Communications (2021)

Article

Correction to: Tuning dual three-dimensional porous copper/graphite composite to achieve diversified utilization of copper current collector for lithium storage

A correction to this paper has been published: https://doi.org/10.1007/s12598-021-01749-6

**a Ma, Zhi-Jia Zhang, Jia-Min Wang, Shi-Hao Sun, Shao-Fei Zhang, Shen Yuan… in Rare Metals (2021)

Article

CLK1/SRSF5 pathway induces aberrant exon skip** of METTL14 and Cyclin L2 and promotes growth and metastasis of pancreatic cancer

Both aberrant alternative splicing and m6A methylation play complicated roles in the development of pancreatic cancer (PC), while the relationship between these two RNA modifications remains unclear.

Shi Chen, Can Yang, Zu-Wei Wang, Jian-Fei Hu… in Journal of Hematology & Oncology (2021)

Article

Screening of osteoarthritis diagnostic markers based on immune-related genes and immune infiltration

Osteoarthritis (OA) is a chronic degenerative disease of the bone and joints. Immune-related genes and immune cell infiltration are important in OA development. We analyzed immune-related genes and immune infi...

Wen-Hua Yuan, Qi-Qi **e, Ke-** Wang, Wei Shen, **ao-Fei Feng… in Scientific Reports (2021)

Article

Anticancer activity of dietary xanthone α-mangostin against hepatocellular carcinoma by inhibition of STAT3 signaling via stabilization of SHP1

Hepatocellular carcinoma (HCC) is one of the most lethal human cancers worldwide. The dietary xanthone α-mangostin (α-MGT) exhibits potent anti-tumor effects in vitro and in vivo. However, the anti-HCC effects...

Hai Zhang, Yu-** Tan, Lin Zhao, Lun Wang, Nai-jie Fu… in Cell Death & Disease (2020)

Article

The effects of autophagy on the replication of Nelson Bay orthoreovirus

Nelson Bay orthoreovirus (NBV) was first isolated over 40 years ago from a fruit bat in Australia. Normally, NBV does not cause human diseases, but recently several NBV strains have been associated with human ...

**ao-Li Tao, Wei Zhao, Wei Tong, **ao-Fang Wang, Li-Li Dou… in Virology Journal (2019)

Article

Effect of cultivation mode on the production of docosahexaenoic acid by Tisochrysis lutea

In this study, Tisochrysis lutea was cultivated in mixotrophic and heterotrophic cultures with glycerol as a carbon source and with glucose and acetate for comparison; autotrophic cultivation was the control grou...

Hao Hu, Lin-Lin Ma, **ao-Fei Shen, Jia-Yun Li, Hou-Feng Wang… in AMB Express (2018)

Article

Effects of Vildagliptin Add-on Insulin Therapy on Nocturnal Glycemic Variations in Uncontrolled Type 2 Diabetes

To investigate whether vildagliptin add-on insulin therapy improves glycemic variations in patients with uncontrolled type 2 diabetes (T2D) compared to patients with placebo therapy.

Feng-fei Li, Yun Shen, Rui Sun, Dan-feng Zhang, **ng **… in Diabetes Therapy (2017)

Article

World Congress Integrative Medicine & Health 2017: Part one

Benno Brinkhaus, Torkel Falkenberg… in BMC Complementary and Alternative Medicine (2017)

Article

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

Andreas Lundqvist, Vincent van Hoef, **aonan Zhang… in Journal for ImmunoTherapy of Cancer (2016)