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Metabolic obesity phenotypes and all-cause mortality among the Chinese oldest-old population: a prospective cohort study
The obesity paradox has been reported among older adults. However, whether the favorable effect of obesity is dependent on metabolic status remains largely unknown. We aimed to explore the association of metab...
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Article
Open AccessChanges of Mycobacterium tuberculosis specific antigen-stimulated CD27−CD38+IFN-γ+CD4+ T cells before and after anti-tuberculosis treatment
The aim of the study was to investigate whether the expression of CD27−CD38+ in interferon (IFN)-γ+CD4+ T cells stimulated by the specific antigen early secreted antigenic target-6 (ESAT-6)/culture filter protein...
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Article
Open AccessConsensus for criteria of running a pediatric inflammatory bowel disease center using a modified Delphi approach
Good quality of care for inflammatory bowel disease (IBD) depends on high-standard management and facility in the IBD center. Yet, there are no clear measures or criteria for evaluating pediatric IBD (PIBD) ce...
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Article
Open AccessA predictive model of response to metoprolol in children and adolescents with postural tachycardia syndrome
The present work was designed to explore whether electrocardiogram (ECG) index-based models could predict the effectiveness of metoprolol therapy in pediatric patients with postural tachycardia syndrome (POTS).
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Article
Open AccessExpert consensus on the monitoring and treatment of sepsis-induced immunosuppression
Emerged evidence has indicated that immunosuppression is involved in the occurrence and development of sepsis. To provide clinical practice recommendations on the immune function in sepsis, an expert consensus...
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Article
Electroacupuncture Attenuates Ischemic Brain Injury and Cellular Apoptosis via Mitochondrial Translocation of Cofilin
To investigate the potential mechanisms of electroacupuncture (EA) to prevent ischemic stroke.
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Article
Open AccessHerbal therapy for ameliorating nonalcoholic fatty liver disease via rebuilding the intestinal microecology
The worldwide prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing, and this metabolic disorder has been recognized as a severe threat to human health. A variety of chemical drugs have been app...
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Article
Open AccessPsychological impact of COVID-19 on medical care workers in China
Medical care workers experienced unprecedented levels of workload and pressure since the outbreak of coronavirus disease 2019 (COVID-19). Little is known about its exact impact on medical care workers and rela...
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Article
VHL-HIF-2α axis-induced SMYD3 upregulation drives renal cell carcinoma progression via direct trans-activation of EGFR
It has been well established that the von Hippel-Lindau/hypoxia-inducible factor α (VHL-HIFα) axis and epidermal growth factor receptor (EGFR) signaling pathway play a critical role in the pathogenesis and pro...
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Article
Open AccessPredictors of five-year relapse rates of youths with substance abuse who underwent a family-oriented therapy program
Substance abuse among young people has become a serious public health problem for years. The risk of relapse among illicit drug use is essential for develo** adequate substance reuse prevention policies. The...
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Article
Open AccessCase report of ocular Kaposi’s sarcoma
Kaposi’s sarcoma (KS) is generally considered a neoplastic disorder of vascular origin and occurs in patients with acquired immunodeficiency syndrome (AIDS) or who have received immunosuppressive treatments af...
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Open AccessXXIV World Allergy Congress 2015
A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts
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Quantitative multivoxel proton MR spectroscopy study of brain metabolites in patients with amnestic mild cognitive impairment: a pilot study
The purpose of this study is to investigate brain metabolic changes in patients with amnestic mild cognitive impairment (aMCI) using multivoxel proton MR spectroscopy (1H-MVS).
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Costs of cervical cancer and precancerous lesions treatment in a publicly financed health care system
Although cervical cancer is the most frequent cancer for women in Taiwan, no examination of its treatment costs has yet been undertaken. This study aimed to investigate the costs of cervical cancer and precanc...
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Effect of electroacupuncture on the bladder function in rats with bladder hyperactivity
观察电针对排尿频率、 骶髓背角血管活性肠肽 (VIP)表达的影响, 探讨针刺抑制大鼠左旋多巴诱发的膀胱机能亢进的神经生物学机制。