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Article
Preparation of (S)-epichlorohydrin using a novel halohydrin dehalogenase by selective conformation adjustment
Chiral epichlorohydrin (ECH) is an attractive intermediate for chiral pharmaceuticals and chemicals preparation. The asymmetric synthesis of chiral ECH using 1,3-dicholoro-2-propanol (1,3-DCP) catalyzed by a h...
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Article
1D Convolutional Seismic Event Classification Method Based on Attention Mechanism and Light Inception Block
Waveforms of artificially induced explosions and collapse events recorded by the seismic network share similarities with natural earthquakes. Failure to identify and screen them in a timely manner can introduc...
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Article
Fault and lithology interpretation for the northern coastal zone of Taizhou based on aeromagnetic data
The northern coastal zone of Taizhou spans three tectonic units: the North China Block, Lower Yangtze Block, and Cathaysian Block. The regional geological structure is complex, magmatic activity is strong, and...
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Article
Synthesis of highly stable Ni nanoparticles via electrostatic self-assembly for enhanced hydrogen storage of MgH2
Magnesium-based hydrides have been widely recognized as an appropriate choice for solid-state hydrogen storage. However, its undesirable thermodynamics and sluggish hydrogenation/dehydrogenation kinetics are m...
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Article
Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBi**g, a Chinese herb-based intravenous formulation
Sepsis, a life-threatening health issue, lacks effective medicine targeting the septic response. In China, treatment combining the intravenous herbal medicine XueBi**g with conventional procedures reduces the...
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Article
Open AccessRisk factors for renal outcomes in children with antineutrophil cytoplasmic antibody-associated vasculitis: a nationwide retrospective study in China
Pediatric antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is a life-threatening systemic vasculitis featured by liability to renal involvement. However, there are few studies on the risk factor...
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Article
Crystalline-amorphous M@MNx (M = Co, Fe, Ni) encapsulated in nitrogen-doped carbon for enhanced efficient and durable hydrogen evolution reaction
Develo** earth-abundant electrocatalysts for hydrogen evolution reaction (HER) is important for the sustainable energy economy. Herein, efficient and stable heterocatalysts consisting of crystalline-amorphou...
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Article
Efficacy of microwave ablation in the treatment of large benign thyroid nodules: a multi-center study
To evaluate the efficacy, safety, and improvement of symptoms by ultrasound-guided microwave ablation (MWA) for patients with large benign thyroid nodules (BTNs).
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Article
Basement characteristics reflected by aeromagnetic data in the northern coastal zone of Taizhou
On the basis of the latest aeromagnetic data of the northern coastal zone of Taizhou, integrated interpretation is performed in this study by combining airborne gravity data, regional geology, and magnetic sus...
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Article
Open AccessNeutralization of Omicron XBB.1 by booster vaccination with BA.4/5 monovalent mRNA vaccine
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Article
Open AccessAutophagy dysfunction contributes to NLRP1 inflammasome-linked depressive-like behaviors in mice
Major depressive disorder (MDD) is a common but severe psychiatric illness characterized by depressive mood and diminished interest. Both nucleotide-binding oligomerization domain, leucine-rich repeat and pyri...
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Article
Description of Nesterenkonia aerolata sp. nov., an actinobacterium isolated from air of manufacturing shop in a pharmaceutical factory
During our studies on the microorganism diversity from air of manufacturing shop in a pharmaceutical factory in Shandong province, China, a Gram-stain-positive, aerobic, cocci-shaped bacterium, designated LY-0111
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Chapter and Conference Paper
Integrated Acid Fracturing and Completion Technology for Carbonate Reservoirs in Sichuan-Chongqing Area
Carbonate reservoirs in Sichuan and Chongqing are characterized by deep burial depth (>4500 m), high formation temperature (>130 ℃), multiple layers, low porosity, low permeability, and high sulfur content, Ho...
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Article
Development of lithium-free P2-type high-sodium content cathode materials with enhanced cycle and air stability for sodium-ion batteries
The effect of partial substitution of Mg for Ni on a high-sodium and lithium-free layered P2-type Na45/54Mg6/54Ni12/54Mn34/54O2 cathode with high initial Coulombic efficiency and excellent cyclic stability has be...
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Article
Sphincter of Oddi Dysfunction Induces Gallstone by Inhibiting the Expression of ABCB11 via PKC-α
The abnormal increase of Oddi sphincter pressure and total bile duct pressure may play an important role in the formation of cholesterol stones, but the specific molecular mechanism is still unclear. This stud...
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Article
Open AccessAdvances in nuclear detection and readout techniques
“A Craftsman Must Sharpen His Tools to Do His Job,” said Confucius. Nuclear detection and readout techniques are the foundation of particle physics, nuclear physics, and particle astrophysics to reveal the nat...
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Article
Prognostic impact of deep learning–based quantification in clinical stage 0-I lung adenocarcinoma
To evaluate the performance of automatic deep learning (DL) algorithm for size, mass, and volume measurements in predicting prognosis of lung adenocarcinoma (LUAD) and compared with manual measurements.
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Article
Targeting proteasomal deubiquitinases USP14 and UCHL5 with b-AP15 reduces 5-fluorouracil resistance in colorectal cancer cells
5-Fluorouracil (5-FU) is the first-line treatment for colorectal cancer (CRC) patients, but the development of acquired resistance to 5-FU remains a big challenge. Deubiquitinases play a key role in the protei...
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Article
Open AccessSDC1 and ITGA2 as novel prognostic biomarkers for PDAC related to IPMN
The existing biomarkers are insufficient for predicting the prognosis of pancreatic ductal adenocarcinoma (PDAC). Intraductal papillary mucinous neoplasm (IPMN) is a precursor to PDAC; therefore, identifying b...
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Article
Open AccessSelf-testing of a single quantum system from theory to experiment
Self-testing allows one to characterise quantum systems under minimal assumptions. However, existing schemes rely on quantum nonlocality and cannot be applied to systems that are not entangled. Here, we introd...
