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Article
Open AccessImaging diagnosis and differential diagnosis of extraskeletal osteosarcoma
The aim of this study was to investigate the clinical, imaging and pathological features of extraskeletal osteosarcoma (EOS) and to improve the understanding of this disease and other similar lesions.
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Article
Open AccessAdjuvant chemotherapy in pancreatic cancer at different AJCC stages: a propensity score matching analysis
In the treatment of resectable pancreatic cancer, adjuvant chemotherapy is viewed as essential. However, it is yet unclear how well adjuvant chemotherapy works at different illness stages. This study aims to i...
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Article
Open AccessThe optimal intravesical maintenance chemotherapy scheme for the intermediate-risk group non-muscle-invasive bladder cancer
Although the current European Association of Urology(EAU) guideline recommends that patients with intermediate-risk non-muscle-invasive bladder cancer (NMIBC) should accept intravesical chemotherapy or Calmett...
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Article
Open AccessAMP-activated protein kinase α2 contributes to acute and chronic hyperuricemic nephropathy via renal urate deposition in a mouse model
Hyperuricemia can induce acute and chronic kidney damage, but the pathological mechanism remains unclear. The potential role of AMP-activated protein kinase (AMPK) α2 in hyperuricemia-induced renal injury was ...
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Article
Open AccessFast-track multidisciplinary treatment versus conventional treatment for colorectal cancer: a multicenter, open-label randomized controlled study
Laparoscopic surgery, fast-track perioperative treatment and XELOX chemotherapy are effective strategies for shortening the duration of hospital stay for cancer patients. This trial aimed to clarify the safety...
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Article
Open AccessRadiomics score: a potential prognostic imaging feature for postoperative survival of solitary HCC patients
Radiomics is an emerging field in oncological research. In this study, we aimed at develo** a radiomics score (rad-score) to estimate postoperative recurrence and survival in patients with solitary hepatocel...
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Article
Open AccessMiR-221/222 promote epithelial-mesenchymal transition by targeting Notch3 in breast cancer cell lines
Basal-like breast cancer (BLBC) is an aggressive subtype with a strong tendency to metastasize. Due to the lack of effective chemotherapy, BLBC has a poor prognosis compared with luminal subtype breast cancer....
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Article
Open AccessChemokine receptor CXCR4 expression in hepatocellular carcinoma patients increases the risk of bone metastases and poor survival
The chemokine and bone marrow-homing receptor CXCR4 is implicated in metastases of various cancers. This study was conducted to analyze the association of CXCR4 expression with hepatocellular carcinoma (HCC) b...