32 Result(s)

Article

Landform and lithospheric development contribute to the assembly of mountain floras in China

Although it is well documented that mountains tend to exhibit high biodiversity, how geological processes affect the assemblage of montane floras is a matter of ongoing research. Here, we explore landform-spec...

Wan-Yi Zhao, Zhong-Cheng Liu, Shi Shi, Jie-Lan Li, Ke-Wang Xu… in Nature Communications (2024)

Article

IGSF6 is a novel biomarker to evaluate immune infiltration in mismatch repair-proficient colorectal cancer

Immunotherapy has dramatically changed the landscape of treatment for colorectal cancer (CRC), but currently lack of effective predictive biomarker, especially for tumors with mismatch repair (MMR) proficiency...

Yu-ming Rong, Yu-cheng Xu, **ao-chuan Chen, Min-er Zhong… in Scientific Reports (2023)

Article

Retraction Note: Mir20a/106a-WTX axis regulates RhoGDIa/CDC42 signaling and colon cancer progression

Gui-fang Zhu, Yang-wei Xu, Jian Li, Hui-lin Niu, Wen-xia Ma… in Nature Communications (2023)

Article

Autonomic function and motor subtypes in Parkinson’s disease: a multicentre cross-sectional study

Autonomic symptoms (AS) are critical in Parkinson’s disease (PD). We aimed to determine the relative significance of clinical factors allowing predictions about incidence of AS, and examine AS profiles among P...

Si-Chun Gu, Rong Shi, Chen Gao, **ao-Lei Yuan, You Wu, Zhen-Guo Liu… in Scientific Reports (2023)

Article

Single-cell analysis of peripheral blood from high-altitude pulmonary hypertension patients identifies a distinct monocyte phenotype

Immune and inflammatory responses have an important function in the pathophysiology of pulmonary hypertension (PH). However, little is known about the immune landscape in peripheral circulation in patients wit...

**n-Hua Wu, Yang-Yang He, Zhang-Rong Chen, Ze-Yuan He, Yi Yan… in Nature Communications (2023)

Article

The Toxoplasma micropore mediates endocytosis for selective nutrient salvage from host cell compartments

Apicomplexan parasite growth and replication relies on nutrient acquisition from host cells, in which intracellular multiplication occurs, yet the mechanisms that underlie the nutrient salvage remain elusive. ...

Wenyan Wan, Hui Dong, De-Hua Lai, Jiong Yang, Kai He, **aoyan Tang… in Nature Communications (2023)

Article

TRIM21 inhibits irradiation-induced mitochondrial DNA release and impairs antitumour immunity in nasopharyngeal carcinoma tumour models

Although radiotherapy can promote antitumour immunity, the mechanisms underlying this phenomenon remain unclear. Here, we demonstrate that the expression of the E3 ubiquitin ligase, tumour cell-intrinsic tripa...

Jun-Yan Li, Yin Zhao, Sha Gong, Miao-Miao Wang, Xu Liu… in Nature Communications (2023)

Article

Author Correction: Comparative metabolomics study on therapeutic mechanism of electro-acupuncture and moxibustion on rats with chronic atrophic gastritis (CAG)

Cai-chun Liu, Jiao-long Chen, **ao-rong Chang, Qi-da He… in Scientific Reports (2022)

Article

Tumor evolution selectively inactivates the core microRNA machinery for immune evasion

Cancer cells acquire genetic heterogeneity to escape from immune surveillance during tumor evolution, but a systematic approach to distinguish driver from passenger mutations is lacking. Here we investigate th...

Tian-Yu Song, Min Long, Hai-**n Zhao, Miao-Wen Zou, Hong-Jie Fan… in Nature Communications (2021)

Article

Dissecting spatial heterogeneity and the immune-evasion mechanism of CTCs by single-cell RNA-seq in hepatocellular carcinoma

Little is known about the transcriptomic plasticity and adaptive mechanisms of circulating tumor cells (CTCs) during hematogeneous dissemination. Here we interrogate the transcriptome of 113 single CTCs from 4...

Yun-Fan Sun, Liang Wu, Shi-** Liu, Miao-Miao Jiang, Bo Hu… in Nature Communications (2021)

Article

PRC2 and EHMT1 regulate H3K27me2 and H3K27me3 establishment across the zygote genome

The formation of zygote is the beginning of mammalian life, and dynamic epigenetic modifications are essential for mammalian normal development. H3K27 di-methylation (H3K27me2) and H3K27 tri-methylation (H3K27...

Tie-Gang Meng, Qian Zhou, Xue-Shan Ma, **ao-Yu Liu, Qing-Ren Meng… in Nature Communications (2020)

Article

Publisher Correction: Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Lars Muhl, Guillem Genové, Stefanos Leptidis, Jian** Liu… in Nature Communications (2020)

Article

Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination

Many important cell types in adult vertebrates have a mesenchymal origin, including fibroblasts and vascular mural cells. Although their biological importance is undisputed, the level of mesenchymal cell heter...

Lars Muhl, Guillem Genové, Stefanos Leptidis, Jian** Liu… in Nature Communications (2020)

Article

A simple and effective method to discern the true commercial Chinese cordyceps from counterfeits

The Chinese cordyceps, a complex of the fungus Ophiocordyceps sinensis and its species-specific host insects, is also called “DongChong**aCao” in Chinese. Habitat degradation in recent decades and excessive harve...

Fu-Li Zhang, **ao-Feng Yang, Dong Wang, Shao-Rong Lei, Ling-An Guo… in Scientific Reports (2020)

Article

A ZEB1/p53 signaling axis in stromal fibroblasts promotes mammary epithelial tumours

Accumulating evidence indicates that the zinc-finger transcription factor ZEB1 is predominantly expressed in the stroma of several tumours. However, the role of stromal ZEB1 in tumour progression remains unexp...

Rong Fu, Chen-Feng Han, Ting Ni, Lei Di, Li-Juan Liu, Wen-Cong Lv… in Nature Communications (2019)

Article

RETRACTED ARTICLE: Mir20a/106a-WTX axis regulates RhoGDIa/CDC42 signaling and colon cancer progression

Wilms tumor gene on the X chromosome (WTX) is a putative tumor suppressor gene in Wilms tumor, but its expression and functions in other tumors are unclear. Colorectal cancer (CRC) is the third leading cause of c...

Gui-fang Zhu, Yang-wei Xu, Jian Li, Hui-lin Niu, Wen-xia Ma… in Nature Communications (2019)

Article

Ginseng oligopeptides protect against irradiation-induced immune dysfunction and intestinal injury

Intestinal injury and immune dysfunction are commonly encountered after irradiation therapy. While the curative abilities of ginseng root have been reported in prior studies, there is little known regarding it...

Li-**a He, Zhao-Feng Zhang, Jian Zhao, Lin Li, Teng Xu, Bin Sun… in Scientific Reports (2018)

Article

Comparative metabolomics study on therapeutic mechanism of electro-acupuncture and moxibustion on rats with chronic atrophic gastritis (CAG)

Some studies have proved that both acupuncture and moxibustion are very effective for the treatment of CAG. However, little is known about therapeutic mechanism of electro-acupuncture and moxibustion on CAG as...

Cai-chun Liu, Jiao-long Chen, **ao-rong Chang, Qi-da He… in Scientific Reports (2017)

Article

Harvesting more grain zinc of wheat for human health

Increasing grain zinc (Zn) concentration of cereals for minimizing Zn malnutrition in two billion people represents an important global humanitarian challenge. Grain Zn in field-grown wheat at the global scale...

**n-** Chen, Yue-Qiang Zhang, Yi-** Tong, Yan-Fang Xue… in Scientific Reports (2017)

Article

Structural analysis of the regulatory mechanism of MarR protein Rv2887 in M. tuberculosis

MarR family proteins are transcriptional regulators that control expression of bacterial proteins involved in metabolism, virulence, stress responses and multi-drug resistance, mainly via ligand-mediated atten...

Yun-Rong Gao, De-Feng Li, Joy Fleming, Ya-Feng Zhou, Ying Liu… in Scientific Reports (2017)