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Article
Open AccessA new diagnostic technique for identifying Angiostrongylus spp. larvae in intermediate snail species by examining the buccal cavity
Angiostrongyliasis is a zoonotic parasitic disease caused by the rat lungworm Angiostrongylus cantonensis. The intermediate hosts of A. cantonensis are gastropods, and snail species such as Pomacea canaliculata p...
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Article
Constructing 2D bismuth-based heterostructure for highly efficient photocatalytic CO2 reduction
Reforming carbon dioxide (CO2) into fuels and valuable chemicals using solar energy holds significant potential for emission reduction and addressing energy supply challenges. The recombination of photocarriers r...
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Article
Effects of Acupotomy on Immobilization-Induced Gastrocnemius Contracture and Fibrosis in Rats via Wnt/β-Catenin Signaling
To determine whether acupotomy ameliorates immobilization-induced muscle contracture and fibrosis via Wnt/β-catenin signaling pathway.
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Article
Determination and parameters calibration of the soybean-bonded particle model based on discrete element method
To determine the desirable bonding parameters of the soybean-bonded particle model for accidentally simulating the working process of a pneumatic soybean seed-metering device. Taking the compressive destructiv...
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Article
Open AccessLandform and lithospheric development contribute to the assembly of mountain floras in China
Although it is well documented that mountains tend to exhibit high biodiversity, how geological processes affect the assemblage of montane floras is a matter of ongoing research. Here, we explore landform-spec...
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Article
Open AccessDUSP22 inhibits lung tumorigenesis by suppression of EGFR/c-Met signaling
DUSP22, an atypical dual-specificity phosphatase enzyme, plays a significant role in regulating multiple kinase signaling pathways by dephosphorylation. Our study demonstrated that decreased DUSP22 expression ...
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Article
Identification of working conditions and prediction of FeO content in sintering process of iron ore fines
The iron oxide (FeO) content had a significant impact on both the metallurgical properties of sintered ores and the economic indicators of the sintering process. Precisely predicting FeO content possessed subs...
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Article
Advancements of Macrophages Involvement in Pathological Progression of Colitis-Associated Colorectal Cancer and Associated Pharmacological Interventions
Intestinal macrophages play crucial roles in both intestinal inflammation and immune homeostasis. They can adopt two distinct phenotypes, primarily determined by environmental cues. These phenotypes encompass ...
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Article
Upregulation of eIF2α by m6A modification accelerates the proliferation of pulmonary artery smooth muscle cells in MCT-induced pulmonary arterial hypertension rats
Pulmonary arterial hypertension (PAH) is a malignant cardiovascular disease. Eukaryotic initiation factor 2α (eIF2α) plays an important role in the proliferation of pulmonary artery smooth muscle cells (PASMCs...
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Article
Edge Electronic States and Direct Bandgap in Si Nanostructures on Silicon Oxide
The nanostructures on silicon oxide, as a new phase of matter, only allows conducting electrons to exist on its surfaces, in which the edge electronic states dramatically provide intriguing insights into the w...
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Article
The dual function of cGAS-STING signaling axis in liver diseases
Numerous liver diseases, such as nonalcoholic fatty liver disease, hepatitis, hepatocellular carcinoma, and hepatic ischemia-reperfusion injury, have been increasingly prevalent, posing significant threats to ...
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Article
Intestinal epithelial Krüppel-like factor 4 alleviates endotoxemia and atherosclerosis through improving NF-κB/miR-34a-mediated intestinal permeability
Maintenance of intestinal barrier function contributes to gastrointestinal homeostasis and therefore cardiovascular diseases. A number of studies show that intestinal permeability is affected by excessive infl...
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Article
Open AccessNaringin attenuates Actinobacillus pleuropneumoniae-induced acute lung injury via MAPK/NF-κB and Keap1/Nrf2/HO-1 pathway
Actinobacillus pleuropneumoniae (APP) causes porcine pleuropneumonia (PCP), which is clinically characterized by acute hemorrhagic, necrotizing pneumonia, and chronic fibrinous pneumonia. Although many measures h...
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Article
A Higher Stomatal Aperture is Associated with the Growth Promotion of Centipedegrass (Eremochloa ophiuroides (Munro) Hack.) Under High Concentrations of Ammonium
The key to improving the efficiency by which acid-soil-growing plants utilize nitrogen is to improve their efficiency of utilizing ammonium. The carbon deficiency is recognized as the main cause of the failure...
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Article
Open AccessTumor-repopulating cells evade ferroptosis via PCK2-dependent phospholipid remodeling
Whether stem-cell-like cancer cells avert ferroptosis to mediate therapy resistance remains unclear. In this study, using a soft fibrin gel culture system, we found that tumor-repopulating cells (TRCs) with st...
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Article
Acoustic emission characteristics in tensile-shear failure of non-persistent jointed rocks with different undulation angles
Tensile-shear failure commonly occurs during the construction of deep in-situ tunnels. In this paper, direct tensile-shear tests were conducted on rock-like specimens containing regular serrated joints using a...
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Article
Open AccessRisk factors for renal outcomes in children with antineutrophil cytoplasmic antibody-associated vasculitis: a nationwide retrospective study in China
Pediatric antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is a life-threatening systemic vasculitis featured by liability to renal involvement. However, there are few studies on the risk factor...
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Article
Open AccessCorrelation of distribution characteristics and dynamic changes of gut microbiota with the efficacy of immunotherapy in EGFR-mutated non-small cell lung cancer
The effects of gut microbiota and metabolites on the responses to immune checkpoint inhibitors (ICIs) in advanced epidermal growth factor receptor (EGFR) wild-type non-small cell lung cancer (NSCLC) have been stu...
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Article
Isorhamnetin Downregulates MMP2 and MMP9 to Inhibit Development of Rheumatoid Arthritis through SRC/ERK/CREB Pathway
To investigate the effect of isorhamnetin on the pathology of rheumatoid arthritis (RA).
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Article
Leachability of potentially toxic elements from soils: New insights into coupled effects of acidification and freeze-thaw
Little was known about the leaching behavior of potentially toxic elements (PTEs) from soils under the interaction between freeze-thaw (F-T) cycle and the solutions of varying pH values. In this study, PTEs le...
