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  1. No Access

    Article

    Effects of 2,3′,4,4′5-pentachlorobiphenyl exposure during pregnancy on epigenetic imprinting and maturation of offspring’s oocytes in mice

    Polychlorinated biphenyls (PCBs) are a class of organic pollutants that have been widely found in the environment. The chemical 2,3′,4,4′5-pentachlorobiphenyl (PCB118) is an important dioxin-like PCB compound ...

    Qi-Long He, Xu-Yu Wei, **ao-Ying Han, Qian Zhou, Hai-Quan Wang… in Archives of Toxicology (2019)

  2. Article

    Open Access

    Adipose afferent reflex is enhanced by TNFα in paraventricular nucleus through NADPH oxidase-dependent ROS generation in obesity-related hypertensive rats

    The adipose afferent reflex (AAR), a sympatho-excitatory reflex, can promote the elevation of sympathetic nerve activity (SNA) and blood pressure (BP). Inflammation in the paraventricular nucleus (PVN) involve...

    Lei Ding, Ying Kang, Hang-Bing Dai, Fang-Zheng Wang… in Journal of Translational Medicine (2019)

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  3. Article

    Open Access

    Electroacupuncture inhibits chronification of the acute pain of knee osteoarthritis: study protocol for a randomized controlled trial

    Previous studies have shown that electroacupuncture (EA) has a significant effect on acute pain, but it has not solved the clinical problem of the chronification of acute pain. Diffuse noxious inhibitory contr...

    Lin-lin Shen, Guo-fu Huang, Wen Tian, Ling-ling Yu, **ao-cui Yuan… in Trials (2015)

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  4. Article

    Corrigendum: Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54

    Nat. Genet. 42, 759–763 (2010); published online 22 August 2010; corrected after print 27 August 2014 In contrast to the version of this article initially published, the authors now find no evidence to support...

    Li-Dong Wang, Fu-You Zhou, Xue-Min Li, Liang-Dan Sun, **n Song, Yan **… in Nature Genetics (2014)

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  5. Article

    Strontium ranelate reduces cartilage degeneration and subchondral bone remodeling in rat osteoarthritis model

    To investigate whether strontium ranelate (SR), a new antiosteoporotic agent, could attenuate cartilage degeneration and subchondral bone remodeling in osteoarthritis (OA).

    De-gang Yu, Hui-feng Ding, Yuan-qing Mao, Ming Liu, Bo Yu… in Acta Pharmacologica Sinica (2013)

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  6. Article

    Efficacy of zoledronic acid in treatment of teoarthritis is dependent on the disease progression stage in rat medial meniscal tear model

    To investigate whether the stage of osteoarthritis (OA) progression influenced the efficacy of the third-generation bisphosphonate zoledronic acid in a rat medial meniscal tear model.

    De-gang Yu, Bo Yu, Yuan-qing Mao, **n Zhao, **ao-qing Wang… in Acta Pharmacologica Sinica (2012)

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  7. No Access

    Article

    Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies a susceptibility locus at PLCE1

    Li Dong Wang and colleagues report a genome wide association study for esophageal squamous cell carcinoma in the Chinese population. They identify two risk loci at PLCE1 and C20orf54.

    Li-Dong Wang, Fu-You Zhou, Xue-Min Li, Liang-Dan Sun, **n Song, Yan **… in Nature Genetics (2010)