Skip to main content

and
  1. No Access

    Article

    Inhibition of USP10 induces myeloma cell apoptosis by promoting cyclin D3 degradation

    The cell cycle regulator cyclin D3 (CCND3) is highly expressed in multiple myeloma (MM) and it promotes MM cell proliferation. After a certain phase of cell cycle, CCND3 is rapidly degraded, which is essential...

    Yu-jia Xu, Kun Zeng, Ying Ren, Chen-yu Mao, Ying-hui Ye in Acta Pharmacologica Sinica (2023)

  2. Article

    Open Access

    KSR2-14–3-3ζ complex serves as a biomarker and potential therapeutic target in sorafenib-resistant hepatocellular carcinoma

    Kinase suppressor of Ras 2 (KSR2) is a regulator of MAPK signaling that is overactivated in most hepatocellular carcinoma (HCC). We sought to determine the role of KSR2 in HCC pathogenesis.

    Chao Gao, Si-wei Wang, Jia-cheng Lu, **ao-qiang Chai, Yuan-cheng Li in Biomarker Research (2022)

  3. No Access

    Article

    Ganoderic acid hinders renal fibrosis via suppressing the TGF-β/Smad and MAPK signaling pathways

    Renal fibrosis is considered as the pathway of almost all kinds of chronic kidney diseases (CKD) to the end stage of renal diseases (ESRD). Ganoderic acid (GA) is a group of lanostane triterpenes isolated from Ga...

    **ao-qiang Geng, Ang Ma, **-zhao He, Liang Wang, Ying-li Jia in Acta Pharmacologica Sinica (2020)

  4. Article

    Corrigendum: Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54

    Nat. Genet. 42, 759–763 (2010); published online 22 August 2010; corrected after print 27 August 2014 In contrast to the version of this article initially published, the authors now find no evidence to support...

    Li-Dong Wang, Fu-You Zhou, Xue-Min Li, Liang-Dan Sun, **n Song, Yan ** in Nature Genetics (2014)

  5. No Access

    Article

    Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies a susceptibility locus at PLCE1

    Li Dong Wang and colleagues report a genome wide association study for esophageal squamous cell carcinoma in the Chinese population. They identify two risk loci at PLCE1 and C20orf54.

    Li-Dong Wang, Fu-You Zhou, Xue-Min Li, Liang-Dan Sun, **n Song, Yan ** in Nature Genetics (2010)

  6. No Access

    Article

    Identification of intermediate and product from methemoglobin-catalyzed oxidation of o-phenylenediamine in two-phase aqueous—organic system

    Methemoglobin (metHb) was used as a mimetic enzyme for peroxidase to catalyze the oxidation reaction of o-phenylenediamine (OPDA) with H2O2 functioning as an oxidant. A reaction intermediate was obtained in two-p...

    De-Jia Li, **-Wen Li, Yu-**ang **e, **ao-Qiang Cai, Guo-Lin Zou in Biochemistry (Moscow) (2005)

  7. No Access

    Article

    Identification of intermediate and product from methemoglobin-catalyzed oxidation of o-phenylenediamine in two-phase aqueous—organic system

    Methemoglobin (metHb) was used as a mimetic enzyme for peroxidase to catalyze the oxidation reaction of o-phenylenediamine (OPDA) with H2O2 functioning as an oxidant. A reaction intermediate was obtained in two-p...

    De-Jia Li, **-Wen Li, Yu-**ang **e, **ao-Qiang Cai, Guo-Lin Zou in Biochemistry (Moscow) (2005)