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  1. Article

    Open Access

    Myricetin mitigates motor disturbance and decreases neuronal ferroptosis in a rat model of Parkinson’s disease

    Ferroptosis is an iron-dependent cell death form characterized by reactive oxygen species (ROS) overgeneration and lipid peroxidation. Myricetin, a flavonoid that exists in numerous plants, exhibits potent ant...

    Si-Chun Gu, Zhi-Guo **e, Min-Jue Gu, Chang-De Wang, Li-Min Xu in Scientific Reports (2024)

  2. No Access

    Article

    Lethal pulmonary thromboembolism in mice induced by intravenous human umbilical cord mesenchymal stem cell-derived large extracellular vesicles in a dose- and tissue factor-dependent manner

    Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have obvious advantages over MSC therapy. But the strong procoagulant properties of MSC-EVs pose a potential risk of thromboembolism, an issue tha...

    Bian-lei Yang, Yao-ying Long, Qian Lei, Fei Gao in Acta Pharmacologica Sinica (2024)

  3. Article

    Open Access

    Optimization of Wet-Spun PEDOT:PSS Fibers for Thermoelectric Applications Through Innovative Triple Post-treatments

    Owing to the high flexibility, low thermal conductivity, and tunable electrical transport property, poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) exhibits promising potential for designin...

    Yu-Yu Deng, **ao-Lei Shi, Ting Wu, Yicheng Yue, Wei-Di Liu in Advanced Fiber Materials (2024)

  4. Article

    Open Access

    Serum cytokines and creatinine/cystatin C ratio as prognostic biomarkers in advanced cancer patients treated with anti-PD-1/PD-L1 therapy

    Immune checkpoint inhibitors (ICIs), specifically targeting the programmed cell death protein-1 or its ligand (PD-1/PD-L1), have been extensively used in the treatment of a spectrum of malignancies, although t...

    Shan-xiu **, Bo-Na Liu, Hong-juan Ji, **g-ran Wu, Bao-lei Li in Supportive Care in Cancer (2024)

  5. Article

    Open Access

    A ResNet mini architecture for brain age prediction

    The brain presents age-related structural and functional changes in the human life, with different extends between subjects and groups. Brain age prediction can be used to evaluate the development and aging of...

    Xuan Zhang, Si-Yuan Duan, Si-Qi Wang, Yao-Wen Chen, Shi-**n Lai in Scientific Reports (2024)

  6. Article

    Open Access

    Boosting thermoelectric performance of single-walled carbon nanotubes-based films through rational triple treatments

    Single-walled carbon nanotubes (SWCNTs)-based thermoelectric materials, valued for their flexibility, lightweight, and cost-effectiveness, show promise for wearable thermoelectric devices. However, their therm...

    Yuan-Meng Liu, **ao-Lei Shi, Ting Wu, Hao Wu, Yuanqing Mao in Nature Communications (2024)

  7. Article

    Open Access

    High Thermoelectric Performance and Flexibility in Rationally Treated PEDOT:PSS Fiber Bundles

    Organic thermoelectric fibers have great potential as wearable thermoelectric textiles because of their one-dimensional structure and high flexibility. However, the insufficient thermoelectric performance, hig...

    Ting Wu, **ao-Lei Shi, Wei-Di Liu, Meng Li, Fang Yue, Pei Huang in Advanced Fiber Materials (2024)

  8. No Access

    Article

    CRF regulates pain sensation by enhancement of corticoaccumbal excitatory synaptic transmission

    Both peripheral and central corticotropin-releasing factor (CRF) systems have been implicated in regulating pain sensation. However, compared with the peripheral, the mechanisms underlying central CRF system i...

    Weinan Zhao, Yu-Mei Yu, **ao-Yi Wang, Sun-Hui **a, Yu Ma in Molecular Psychiatry (2024)

  9. Article

    Open Access

    RGA1 regulates grain size, rice quality and seed germination in the small and round grain mutant srg5

    Generating elite rice varieties with high yield and superior quality is the main goal of rice breeding programs. Key agronomic traits, including grain size and seed germination characteristics, affect the fina...

    **a Yang, Jun Lu, Wu-Jian Shi, Yu-Hao Chen, Jia-Wen Yu, Sai-Hua Chen in BMC Plant Biology (2024)

  10. Article

    Open Access

    Evaluation of the efficacy of trigger points combined with extracorporeal shock waves in the treatment of plantar fasciitis: heel temperature and plantar pressure

    Plantar fasciitis (PF) is the most common cause of heel pain. Among conservative treatments, extracorporeal shock wave therapy (ESWT) is considered effective for refractory PF. Studies have shown that applying...

    Bo Wang, **ao-Lei Wang, Yan-Tao Ma, Wei Wu, Yong-Jun Zheng in BMC Musculoskeletal Disorders (2024)

  11. No Access

    Article

    A Transformer-Assisted Cascade Learning Network for Choroidal Vessel Segmentation

    As a highly vascular eye part, the choroid is crucial in various eye disease diagnoses. However, limited research has focused on the inner structure of the choroid due to the challenges in obtaining sufficient...

    Yang Wen 温 阳, Yi-Lin Wu 吴依林, Lei Bi 毕 磊 in Journal of Computer Science and Technology (2024)

  12. No Access

    Article

    A novel human single-domain antibody-drug conjugate targeting CEACAM5 exhibits potent in vitro and in vivo antitumor activity

    Leveraging the specificity of antibody to deliver cytotoxic agent into tumor, antibody-drug conjugates (ADCs) have become one of the hotspots in the development of anticancer therapies. Although significant pr...

    **ao-yi Zhu, Quan-xiao Li, Yu Kong, Ke-ke Huang, Gang Wang in Acta Pharmacologica Sinica (2024)

  13. Article

    Open Access

    Machine learning-based extrachromosomal DNA identification in large-scale cohorts reveals its clinical implications in cancer

    The clinical implications of extrachromosomal DNA (ecDNA) in cancer therapy remain largely elusive. Here, we present a comprehensive analysis of ecDNA amplification spectra and their association with clinical ...

    Shixiang Wang, Chen-Yi Wu, Ming-Ming He, Jia-**n Yong in Nature Communications (2024)

  14. No Access

    Article

    Huangqin Decoction Delays Progress of Colitis-Associated Carcinogenesis by Regulating Nrf2/HO-1 Antioxidant Signal Pathway in Mice

    To investigate the effect of Huangqin Decoction (HQD) on nuclear factor erythroid 2 related-factor 2 (Nrf2)/heme oxygenase (HO-1) signaling pathway by inducing the colitis-associated carcinogenesis (CAC) model...

    Li-mei Gu, He-zhong Li, Lei Gao, Hui Li in Chinese Journal of Integrative Medicine (2024)

  15. Article

    Open Access

    Comparison of efficacy between endoscope-assisted anterior cervical discectomy and fusion (ACDF) and open ACDF in the treatment of single-segment cervical spondylotic myelopathy

    In this study, we compared the clinical efficacy of endoscope-assisted anterior cervical discectomy and fusion (ACDF) with open ACDF in the treatment of single-segment cervical spondylotic myelopathy.

    Zhi-Peng Wu, Zhao-yong Wei, **ao-Lei Song in Journal of Orthopaedic Surgery and Research (2024)

  16. Article

    Open Access

    Plastid genome and its phylogenetic implications of Asiatic Spiraea (Rosaceae)

    Spiraea L. is a genus comprising approximately 90 species that are distributed throughout the northern temperate regions. China is recognized as the center of species diversity for this genus, hosting more than 7...

    Shu-Yan Zhang, Hai-Fei Yan, Lei Wei, Tong-Jian Liu, Lin Chen, Gang Hao in BMC Plant Biology (2024)

  17. No Access

    Book and Conference Proceedings

    Health Information Processing

    9th China Health Information Processing Conference, CHIP 2023, Hangzhou, China, October 27–29, 2023, Proceedings

    Hua Xu, Qingcai Chen, Hongfei Lin, Fei Wu in Communications in Computer and Information Science (2024)

  18. No Access

    Book

  19. No Access

    Book

  20. No Access

    Article

    Adverse effect of niobium and boron on hot deformation behavior of sulfur-containing steel

    The hot deformation behaviors of sulfur-containing gear steel 20MnCr5 containing three different contents of Nb and B (0, 0.021%Nb, and 0.024%Nb–0.0022%B) were investigated. Hot compression and tenssion tests ...

    Guo-ning He, Shi-qi Wan, Bo Jiang in Journal of Iron and Steel Research Interna… (2024)

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