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  1. Article

    Open Access

    Extracellular matrix protein 1 (ECM1) is a potential biomarker in B cell acute lymphoblastic leukemia

    B cell acute lymphoblastic leukemia (ALL) is characterized by the highly heterogeneity of pathogenic genetic background, and there are still approximately 30–40% of patients without clear molecular markers. To...

    Li-**n Wu, Ming-Yue Zhao, Nan Yan, Ya-Lan Zhou in Clinical and Experimental Medicine (2024)

  2. No Access

    Article

    ASO Visual Abstract: Dynamic Analysis of the Impact of Micropapillary Component on Different Recurrence Patterns of Pathological Stage IA3 Lung Adenocarcinoma—A Multicenter, Retrospective Study

    Shao-jun Xu MD, Chao Chen MD, Jia-hua Tu MD in Annals of Surgical Oncology (2024)

  3. No Access

    Article

    Dynamic Analysis of the Impact of Micropapillary Component on Different Recurrence Patterns of Pathological Stage IA3 Lung Adenocarcinoma: A Multicenter, Retrospective Study

    This study aimed to evaluate the dynamic impact of the micropapillary (MIP) component on local recurrence (LR), distant metastasis (DM), and multiple recurrence (MR) of pathological stage IA3 lung adenocarcinoma.

    Shao-jun Xu MD, Chao Chen MD, Jia-hua Tu MD in Annals of Surgical Oncology (2024)

  4. No Access

    Article

    Mutations in DEAD/H-box helicase 11 correlate with increased relapse risk in adults with acute myeloid leukaemia with normal cytogenetics

    Ya-Lan Zhou, Ming-Yue Zhao, Robert Peter Gale, Hao Jiang, Qian Jiang in Leukemia (2024)

  5. No Access

    Article

    High WT1 expression predicted induction chemotherapy failure in acute myeloid leukemia patients with non-favorable cytogenetic risk

    The prognostic significance of WT1 expression at diagnosis in acute myeloid leukemia (AML) remains obscure, and subgroup analysis is the way for clarification. We previously reported the results in t(8;21) AML. I...

    Nan Xu, Wen-Min Chen, Ling-Di Li, Ling-Yu Long in Clinical and Experimental Medicine (2023)

  6. No Access

    Article

    ASO Visual Abstract: A Multi-Institutional Study Analyzing the Combined Effect of Micropapillary Component and Consolidation-to-Tumor Ratio Exceeding 0.5 on the Prognosis for Pathologic Stage IA3 Lung Adenocarcinoma

    Shao-jun Xu MD, Jia-hua Tu MD, Hui Chen MD, Ren-he Yan MD in Annals of Surgical Oncology (2023)

  7. No Access

    Article

    A Multi-institutional Analysis of the Combined Effect of Micropapillary Component and Consolidation-to-Tumor Ratio >0.5 on the Prognosis of Pathological, Stage IA3, Lung Adenocarcinoma

    The study investigated the synergistic effect of the micropapillary (MIP) component and consolidation-to-tumor ratio (CTR) on the recurrence and survival of patients with pathologic stage IA3 lung adenocarcinoma.

    Shao-jun Xu MD, Jia-hua Tu MD, Hui Chen MD, Ren-he Yan MD in Annals of Surgical Oncology (2023)

  8. Article

    Open Access

    Monitoring of post-transplant MLL-PTD as minimal residual disease can predict relapse after allogeneic HSCT in patients with acute myeloid leukemia and myelodysplastic syndrome

    The mixed-lineage leukemia (MLL) gene is located on chromosome 11q23. The MLL gene can be rearranged to generate partial tandem duplications (MLL-PTD), which occurs in about 5-10% of acute myeloid leukemia (AML) ...

    Jun Kong, Meng-Ge Gao, Ya-Zhen Qin, Yu Wang, Chen-Hua Yan, Yu-Qian Sun in BMC Cancer (2022)

  9. No Access

    Article

    Profiles of NK cell subsets are associated with successful tyrosine kinase inhibitor discontinuation in chronic myeloid leukemia and changes following interferon treatment

    Recent studies have shown that approximately 50% of patients with chronic myeloid leukemia (CML) receiving tyrosine kinase inhibitor (TKI) therapy with a sustained deep molecular response (DMR) (BCR-ABL1IS ≤ 0.01...

    Jun Kong, Ya-zhen Qin, **ao-Su Zhao, Yue Hou, Kai-yan Liu in Annals of Hematology (2021)

  10. Article

    Open Access

    Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection: a randomized trial

    It’s a challenge for detecting the therapeutic targets of a polypharmacological drug from variations in the responsed networks in the differentiated populations with complex diseases, as stable coronary heart ...

    Jun Liu, Dan-Dan Li, Wei Dong, Yu-Qi Liu in Signal Transduction and Targeted Therapy (2021)

  11. No Access

    Article

    Minimal residual disease monitoring and preemptive immunotherapies for frequent 11q23 rearranged acute leukemia after allogeneic hematopoietic stem cell transplantation

    The prognosis of 11q23/KMT2A-rearranged (KMT2A-r) acute leukemia (AL) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is poor. Minimal residual disease (MRD) is an important prognostic factor...

    **g Liu, **ao-Hui Zhang, Lan-** Xu, Yu Wang, Chen-Hua Yan in Annals of Hematology (2021)

  12. Article

    Open Access

    The impact of the combination of KIT mutation and minimal residual disease on outcome in t(8;21) acute myeloid leukemia

    Ya-Zhen Qin, Qian Jiang, Yu Wang, Hao Jiang, Lan-** Xu in Blood Cancer Journal (2021)

  13. Article

    Open Access

    Wilms’ tumor gene 1 is an independent prognostic factor for pediatric acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation

    Sequential monitoring of Wilms’ tumor gene 1 (WT1) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) could predict relapse in adult acute myeloid leukemia (AML). However, the prognostic role...

    Dao-**ng Deng, Juan-Juan Wen, Yi-Fei Cheng, **ao-Hui Zhang, Lan-** Xu in BMC Cancer (2021)

  14. No Access

    Article

    The predictive value of minimal residual disease when facing the inconsistent results detected by real-time quantitative PCR and flow cytometry in NPM1-mutated acute myeloid leukemia

    For acute myeloid leukemia (AML) with nucleophosmin 1 mutation (NPM1m), multiparameter flow cytometry (FCM) and real-time quantitative polymerase chain reaction (RQ-PCR) are used to monitor minimal residual disea...

    Meng-Ge Gao, Guo-Rui Ruan, Ying-Jun Chang, Yan-Rong Liu in Annals of Hematology (2020)

  15. No Access

    Article

    The prognostic significance of Wilms’ tumor gene 1 (WT1) expression at diagnosis in adults with Ph-negative B cell precursor acute lymphoblastic leukemia

    The prognostic significance of Wilms’ tumor gene 1 (WT1) expression at diagnosis in adults with B cell precursor acute lymphoblastic leukemia (BCP-ALL) remains poorly understood. A total of 257 adults with Ph-...

    Ya-Zhen Qin, Qian Jiang, Lan-** Xu, Hao Jiang, Yu Wang in Annals of Hematology (2019)

  16. No Access

    Article

    Incidence, risk factors and outcomes of sinusoidal obstruction syndrome after haploidentical allogeneic stem cell transplantation

    Hepatic sinusoidal obstruction syndrome (SOS) has been rarely studied after haploidentical donor (HID) allogeneic hematopoietic stem cell transplantation (allo-HSCT). We performed a retrospective multicentre s...

    Xuan Cai, ** Wu, Ruo-Yun Gui, Qiu-Sha Huang, **ao Liu, Ya-Zhen Qin in Annals of Hematology (2019)

  17. No Access

    Article

    Identification of a novel CPSF6-RARG fusion transcript in acute myeloid leukemia resembling acute promyelocytic leukemia

    Ya-Zhen Qin, **ao-Jun Huang, Hong-Hu Zhu in Leukemia (2018)

  18. Article

    Open Access

    Heterogeneous prognosis among KIT mutation types in adult acute myeloid leukemia patients with t(8;21)

    Ya-Zhen Qin, Hong-Hu Zhu, Qian Jiang, Lan-** Xu, Hao Jiang in Blood Cancer Journal (2018)

  19. No Access

    Article

    Leukemia-propagating cells demonstrate distinctive gene expression profiles compared with other cell fractions from patients with de novo Philadelphia chromosome-positive ALL

    Relapse remains one of the major obstacles in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) even after allogeneic hematopoietic stem cell transplantation. The persistence of leukemia-prop...

    Hong-Yan Zhao, Yang Song, **e-Na Cao, Ya-Zhen Qin, Yue-Yun Lai in Annals of Hematology (2018)

  20. No Access

    Article

    CTLA-4 polymorphisms are associated with treatment outcomes of patients with multiple myeloma receiving bortezomib-based regimens

    Single-nucleotide polymorphisms (SNPs) of cytotoxic T lymphocyte antigen-4 (CTLA-4) are important risk factors associated with autoimmune diseases and malignancies. This study explored the association of CTLA-...

    **ao-Ying Qin, ** Lu, Guo-Xuan Li, Lei Wen, Yang Liu, Lan-** Xu in Annals of Hematology (2018)

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