1,203 Result(s)
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**ao-Hui Chen
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Article
Brain-Targeting Emodin Mitigates Ischemic Stroke via Inhibiting AQP4-Mediated Swelling and Neuroinflammation
Failure to achieve target-specific delivery to ischemic brain sites has hampered the clinical efficacy of newly developed therapies for ischemic stroke. Emodin, an active ingredient isolated from traditional C...
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Open AccessCorrelation between serum trimethylamine-N-oxide and body fat distribution in middle-aged and older adults: a prospective cohort study
Trimethylamine-N-oxide (TMAO) is linked with obesity, while limited evidence on its relationship with body fat distribution. Herein, we investigated the associations between serum TMAO and longitudinal change ...
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Analysis of Phenotypes Associated with Deficiency of PAX6 Haplotypes in Chinese Aniridia Families
To examine the clinical phenotype and genetic deficiencies present in Chinese aniridia families with PAX6 haplotype deficiency.
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CRISPR-array-mediated imaging of non-repetitive and multiplex genomic loci in living cells
Dynamic imaging of genomic loci is key for understanding gene regulation, but methods for imaging genomes, in particular non-repetitive DNAs, are limited. We developed CRISPRdelight, a DNA-labeling system base...
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Emission characteristics and control technology of heavy metals during collaborative treatment of municipal solid waste incineration fly ash in iron ore sintering process
The municipal solid waste incineration fly ash (MSWI-FA) contains a large amount of heavy metals, and the process of iron ore sintering and treating fly ash needs to pay attention to the migration characterist...
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Open AccessGlobal incidence and mortality trends of gastric cancer and predicted mortality of gastric cancer by 2035
To study the historical global incidence and mortality trends of gastric cancer and predicted mortality of gastric cancer by 2035.
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Correction: ASO Visual Abstract: A Novel Classification System of Renal Hilar Tumors for Surgical Guidance: Technique, Outcome, and Safety
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Article
Salvage haploidentical transplantation for graft failure after first haploidentical allogeneic stem cell transplantation: an updated experience
Graft failure is a fatal complication following allogeneic stem cell transplantation where a second transplantation is usually required for salvage. However, there are no recommended regimens for second transp...
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Open AccessA Phase 3, Randomized, Controlled Trial Evaluating the Efficacy and Safety of Ropeginterferon Alfa-2b in Patients with Moderate COVID-19
Ropeginterferon alfa-2b is a novel mono-pegylated proline-interferon. This clinical study aimed to evaluate its antiviral efficacy of ropeginterferon alfa-2b against SARS-CoV-2 infection.
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Open AccessSpray pyrolysis-derived W-doped MoSe2/rGO paper-like microspheres: optimization of microstructure and mesostructure for enhanced lithium storage
Two-dimensional MoSe2 is a promising candidate for lithium-ion battery anodes. However, its conductivity and lithium storage volumetric effect still need to be optimized. In this work, W-doped MoSe2/rGO paper-lik...
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Article
Open AccessExome sequencing and genome-wide association analyses unveils the genetic predisposition in hydroxychloroquine retinopathy
To unveil the candidate susceptibility genes in chloroquine/hydroxychloroquine (CQ/HCQ) retinopathy using whole exome sequencing (WES) and genome-wide association study (GWAS).
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ASO Visual Abstract: A Novel Classification System of Renal Hilar Tumors for Surgical Guidance: Technique, Outcome, and Safety
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Article
Publisher Correction: E3 ubiquitin ligase UBR5 modulates circadian rhythm by facilitating the ubiquitination and degradation of the key clock transcription factor BMAL1
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Article
3D Graphene Nanosheets Crosslinked Core–Shell FeS2@N, S Co-Doped Porous Carbon for Improved Lithium/Sodium Storage Performance
Transition metal sulfides (TMS) hold great promise as anode materials for Li+/Na+ storage. However, their practical application still faces several challenges, such as inadequate electrical conductivity, substant...
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Article
Open AccessLandform and lithospheric development contribute to the assembly of mountain floras in China
Although it is well documented that mountains tend to exhibit high biodiversity, how geological processes affect the assemblage of montane floras is a matter of ongoing research. Here, we explore landform-spec...
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A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease
With the implementation of the 11th edition of the International Classification of Diseases (ICD-11) and the publication of the metabolic dysfunction-associated fatty liver disease (MAFLD) nomenclature in 2020...
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Open AccessDUSP22 inhibits lung tumorigenesis by suppression of EGFR/c-Met signaling
DUSP22, an atypical dual-specificity phosphatase enzyme, plays a significant role in regulating multiple kinase signaling pathways by dephosphorylation. Our study demonstrated that decreased DUSP22 expression ...
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Article
Development of accumulative roll bonding for metallic composite material preparation and mechanical/functional applications
Accumulative roll bonding (ARB) is a severe plastic deformation method to prepare the metallic composite material by physical method at room to elevate temperature, without the generation of additional waste s...
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Article
Numerical Study of Two Opposing Weak Polyelectrolyte Brushes by the Self-consistent Field Theory
The self-consistent field theory (SCFT) was employed to numerically study the interaction and interpenetration between two opposing weak polyelectrolyte (PE) brushes formed by grafting weak PE chains onto the ...
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Article
Parameter optimization of the observation system for the South Yellow Sea strong shielding layer based on seismic illumination analysis
The seismic data of the Laoshan Uplift in the South Yellow Sea Basin reveal a low signal-to-noise ratio and low reflection signal energy in the deep Mesozoic–Paleozoic strata. The main reason is that the Mesoz...
