3 Result(s)
within
English
Biomedicine
Immunology
Neurology
**ao-Fen Wang
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Article
Open AccessSystemic administration of urocortin after intracerebral hemorrhage reduces neurological deficits and neuroinflammation in rats
Intracerebral hemorrhage (ICH) remains a serious clinical problem lacking effective treatment. Urocortin (UCN), a novel anti-inflammatory neuropeptide, protects injured cardiomyocytes and dopaminergic neurons....
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Article
Open AccessLRP1 modulates the microglial immune response via regulation of JNK and NF-κB signaling pathways
Neuroinflammation is characterized by microglial activation and the increased levels of cytokines and chemokines in the central nervous system (CNS). Recent evidence has implicated both beneficial and toxic ro...
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Article
Open AccessIdentification of the minimal active soluble TREM2 sequence for modulating microglial phenotypes and amyloid pathology
TREM2 is a microglial receptor genetically linked to the risk for Alzheimer’s disease (AD). The cerebrospinal fluid (CSF) levels of soluble TREM2 (sTREM2) have emerged as a valuable biomarker for the disease p...
