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Article
Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC
Youwen Zhou and Xue-Jun Zhang and colleagues report a genome-wide association study of generalized vitiligo, a common autoimmune disorder characterized by loss of melanocytes and depigmentation. The authors id...
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Article
Genome-wide association study identifies two new susceptibility loci for atopic dermatitis in the Chinese Han population
Xue-Jun Zhang, Zhi-Rong Yao and colleagues report a genome-wide association study for atopic dermatitis in the Chinese Han population. They identified two new susceptibility loci at 5q22 and 20q13.
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Article
Open AccessUpregulation of the proto-oncogene Bmi-1 predicts a poor prognosis in pediatric acute lymphoblastic leukemia
Bmi-1, the B cell-specific moloney murine leukemia virus insertion site 1, is a member of the Polycomb-group (PcG) family and acts as an oncogene in various tumors; however, its expression related to the progn...
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Article
Open AccessVEGFR2 promotes tumorigenesis and metastasis in a pro-angiogenic-independent way in gastric cancer
VEGF/VEGFR2 pathway is the central therapeutic target in anti-angiogenic treatment in multiple cancers. However, little work has been carried out concerning the pro-malignancy functions of VEGFR2 that are inde...