4 Result(s)

Article

Accumulation of free cholesterol and oxidized low-density lipoprotein is associated with portal inflammation and fibrosis in nonalcoholic fatty liver disease

Macrophages engulf oxidized-LDL (oxLDL) leading to accumulation of cellular cholesterol and formation of foam cells, which is a hallmark of atherosclerosis. Moreover, recent studies showed that accumulation of...

Cheng-Maw Ho, Shu-Li Ho, Yung-Ming Jeng, Yu-Sheng Lai… in Journal of Inflammation (2019)

Article

Globotriaosylsphingosine (lyso-Gb3) might not be a reliable marker for monitoring the long-term therapeutic outcomes of enzyme replacement therapy for late-onset Fabry patients with the Chinese hotspot mutation (IVS4+919G>A)

In Taiwan, DNA-based newborn screening showed a surprisingly high incidence (1/875 in males and 1/399 in females) of a cardiac Fabry mutation (IVS4 + 919G > A). However, the natural course, long-term treatment...

Hao-Chuan Liu, Hsiang-Yu Lin, Chia-Feng Yang… in Orphanet Journal of Rare Diseases (2014)

Article

Race differences: modeling the pharmacodynamics of rosuvastatin in Western and Asian hypercholesterolemia patients

To evaluate race differences in the pharmacodynamics of rosuvastatin in Western and Asian hypercholesterolemia patients using a population pharmacodynamic (PPD) model generated and validated using published cl...

Juan Yang, Lu-** Li, Kun Wang, Ying-chun He, Yu-cheng Sheng… in Acta Pharmacologica Sinica (2011)

Article

Erratum to: Antimetastatic activity of MONCPT in preclinical melanoma mice model

**ao-Chun Yang, Chong-**ng Tu, Pei-Hua Luo, Hong Zhu… in Investigational New Drugs (2010)