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Porcupine inhibitor CGX1321 alleviates heart failure with preserved ejection fraction in mice by blocking WNT signaling

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  1. Article

    Open Access

    Accumulation of free cholesterol and oxidized low-density lipoprotein is associated with portal inflammation and fibrosis in nonalcoholic fatty liver disease

    Macrophages engulf oxidized-LDL (oxLDL) leading to accumulation of cellular cholesterol and formation of foam cells, which is a hallmark of atherosclerosis. Moreover, recent studies showed that accumulation of...

    Cheng-Maw Ho, Shu-Li Ho, Yung-Ming Jeng, Yu-Sheng Lai in Journal of Inflammation (2019)

  2. Article

    Race differences: modeling the pharmacodynamics of rosuvastatin in Western and Asian hypercholesterolemia patients

    To evaluate race differences in the pharmacodynamics of rosuvastatin in Western and Asian hypercholesterolemia patients using a population pharmacodynamic (PPD) model generated and validated using published cl...

    Juan Yang, Lu-** Li, Kun Wang, Ying-chun He, Yu-cheng Sheng in Acta Pharmacologica Sinica (2011)

  3. Article

    Open Access

    Expressions and clinical significances of CD133 protein and CD133 mRNA in primary lesion of gastric adenocacinoma

    To study on expressions and clinical significances of CD133 protein and CD133 mRNA in primary lesion of gastric adenocarcinoma (GC).

    Ji-wei Yu, Peng Zhang, Ju-gang Wu in Journal of Experimental & Clinical Cancer … (2010)