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  1. Article

    Open Access

    A Phase 3, Randomized, Controlled Trial Evaluating the Efficacy and Safety of Ropeginterferon Alfa-2b in Patients with Moderate COVID-19

    Ropeginterferon alfa-2b is a novel mono-pegylated proline-interferon. This clinical study aimed to evaluate its antiviral efficacy of ropeginterferon alfa-2b against SARS-CoV-2 infection.

    Wang-Da Liu, Po-Hao Feng, Chien-Yu Cheng in Infectious Diseases and Therapy (2024)

  2. Article

    Open Access

    Specific convulsions and brain damage in children hospitalized for Omicron BA.5 infection: an observational study using two cohorts

    SARS-CoV-2 continues to mutate over time, and reports on children infected with Omicron BA.5 are limited. We aimed to analyze the specific symptoms of Omicron-infected children and to improve patient care.

    Yuan-Yuan Pei, Hong-Li Wang, Gen-Quan Yin, Yi Xu in World Journal of Pediatrics (2024)

  3. No Access

    Article

    Soil microbial community in lead smelting area and the role of sulfur-oxidizing bacteria

    The long-term operation of the lead smelter has brought serious heavy metal pollution to the surrounding soil. The microbial community structure and composition of heavy metal contaminated soil is important fo...

    Chuan Wu 吴川, Hong-ren Chen 陈虹任, Yong-** Lu 陆永** in Journal of Central South University (2024)

  4. Article

    Open Access

    Comparing transfusion reactions between pre-storage and post-storage leukoreduced apheresis platelets: an analysis using propensity score matching

    Transfusion reactions induced by platelet transfusions may be reduced and alleviated by leukocyte reduction of platelets. Although leukoreduction of apheresis platelets can be performed either pre-storage or p...

    Sheng-Hsuan Chien, Hsin-Yi Huang, Ying-Ju Chen, Yu-Chen Tsai in Annals of Hematology (2024)

  5. Article

    Open Access

    Gene variants and clinical characteristics of children with sitosterolemia

    To enhance the detection, management and monitoring of Chinese children afflicted with sitosterolemia by examining the physical characteristics and genetic makeup of pediatric patients.

    Rui Gu, Hui Wang, Chun-Lin Wang, Mei Lu, Miao Miao in Lipids in Health and Disease (2024)

  6. No Access

    Article

    Random and site-specific radiolabeling of [89Zr]Zr-DFO-anti-PD-L1-mAb iPET tracer

    Zirconium-89 radiolabeled immuno-positron emission tomography (89Zr-iPET) has become a critical tool for patient stratification before and after immunotherapies for therapeutic evaluation. In this study, random a...

    Yi-Ching Lin, Chao-Wei Yang, Shih-Chuan Tsai in Journal of Radioanalytical and Nuclear Che… (2024)

  7. Article

    Open Access

    Relationship between shoulder and elbow range of motion and ultrasonographic structural abnormalities in the elbow of Taiwanese high school baseball players

    Ultrasonographic structural abnormalities are regarded as one of the risk factors of elbow injuries. Elbow injuries are commonly associated with decreased shoulder/elbow range of motion (ROM). The purpose of t...

    Yi Lu, Poyu Chen, Wen-Yi Chou in BMC Sports Science, Medicine and Rehabilit… (2024)

  8. No Access

    Article

    High incidence of EDNRB gene mutation in seven southern Chinese familial cases with Hirschsprung’s disease

    Hirschsprung’s disease (HSCR) is the leading cause of neonatal functional intestinal obstruction, which has been identified in many familial cases. HSCR, a multifactorial disorder of enteric nervous system (EN...

    Hui-yang Ding, Wen Lei, Shang-jie **ao, Hua Deng in Pediatric Surgery International (2024)

  9. Article

    Open Access

    Efficacy of Qingpeng ointment (a Tibetan medicine) for acute gouty arthritis: a multi-center, randomized, double-blind, placebo-controlled trial

    This study aims to assess the efficacy and safety of Qingpeng ointment (QPO), a Tibetan medicine for alleviating symptoms in individuals with acute gouty arthritis (AGA).

    Ya-xi Shang, Shu-feng Wei, Ke-peng Yang in BMC Complementary Medicine and Therapies (2024)

  10. No Access

    Book and Conference Proceedings

    Blended Learning. Intelligent Computing in Education

    17th International Conference on Blended Learning, ICBL 2024, Macao SAR, China, July 29 – August 1, 2024, Proceedings

    Will W. K. Ma, Chen Li, Chun Wai Fan in Lecture Notes in Computer Science (2024)

  11. No Access

    Article

    Fungal diversity notes 1717–1817: taxonomic and phylogenetic contributions on genera and species of fungal taxa

    As the continuation of Fungal Diversity Notes series, the current paper is the 16th contribution to this series. A total of 103 taxa from seven classes in Ascomycota and Basidiomycota are included here. Of these ...

    Shi-Liang Liu, Xue-Wei Wang, Guo-Jie Li, Chun-Ying Deng, Walter Rossi in Fungal Diversity (2024)

  12. No Access

    Article

    MRI radiomics for predicting poor disease-free survival in muscle invasive bladder cancer: the results of the retrospective cohort study

    To develop an MRI radiomic nomogram capable of identifying muscle invasive bladder cancer (MIBC) patients with high-risk molecular characteristics related to poor 2-year disease-free survival (DFS).

    Zhi-chang Fan, Lu Zhang, Guo-qiang Yang, Shuo Li, Jun-ting Guo in Abdominal Radiology (2024)

  13. No Access

    Article

    Optimization and Minimum-Energy Approaches for Private Message Security in the Wavelet Domain of Audio Signals

    In the field of embedding digital information or private message into an audio signal, signal-to-noise ratio (SNR) and bit error rate (BER) are commonly performance indexes in measuring the distortion and robu...

    Shuo-Tsung Chen, Hao-Chun Lu in Circuits, Systems, and Signal Processing (2023)

  14. No Access

    Article

    Two-thiols-regulated fabrication of plasmonic nanoparticles with co-enhanced Raman scattering and circular dichroism responses

    Plasmonic nanoparticles (PNPs) with stable nanogaps are important to achieve strong, uniform and quantitative gap-enhanced Raman scattering (GERS) signals. Chiral PNPs with plasmonic circular dichroism (PCD) r...

    Jia-Qi Chen, Han-Bo Li, ** Lu, **ao-Yang Liu, Wei Feng, Pan Wang in Rare Metals (2023)

  15. Article

    Open Access

    Prediction of clinically significant prostate cancer through urine metabolomic signatures: A large-scale validated study

    Currently, there are no accurate markers for predicting potentially lethal prostate cancer (PC) before biopsy. This study aimed to develop urine tests to predict clinically significant PC (sPC) in men at risk.

    Hsiang-Po Huang, Chung-Hsin Chen, Kai-Hsiung Chang in Journal of Translational Medicine (2023)

  16. Article

    Open Access

    URI alleviates tyrosine kinase inhibitors-induced ferroptosis by reprogramming lipid metabolism in p53 wild-type liver cancers

    The clinical benefit of tyrosine kinase inhibitors (TKIs)-based systemic therapy for advanced hepatocellular carcinoma (HCC) is limited due to drug resistance. Here, we uncover that lipid metabolism reprogramm...

    Zhiwen Ding, Yufei Pan, Taiyu Shang, Tianyi Jiang, Yunkai Lin in Nature Communications (2023)

  17. No Access

    Article

    Real-world treatment outcome with protease inhibitor direct-acting antiviral in advanced hepatitis C cirrhosis: a REAL-C study

    Current guidelines discourage the use of direct-acting antiviral (DAA) containing protease-inhibitor (PI) in advanced HCV cirrhosis. We aimed to compare the real-world tolerability of PI vs. non-PI DAA regimen...

    Yu Jun Wong, Sally Tran, Chung-Feng Huang, Yao-Chun Hsu in Hepatology International (2023)

  18. No Access

    Article

    The association of bisphenol A and paraben exposure with sensorineural hearing loss in children

    Bisphenol A (BPA) and parabens (PBs) are chemicals that are extensively used in personal care products (PCPs). In early childhood development, hearing is critical to speech and language development, communicat...

    Chia-Huang Chang, Chun-Ting Lu in Environmental Science and Pollution Resear… (2023)

  19. Article

    Open Access

    Inhibition of GSDMD-mediated pyroptosis triggered by Trichinella spiralis intervention contributes to the alleviation of DSS-induced ulcerative colitis in mice

    Inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), is increasing worldwide. Although there is currently no completely curative treatment, helminthic therapy shows cer...

    Zhen-Rong Ma, Zhuo-Lin Li, Ni Zhang, Bin Lu, Xuan-Wu Li in Parasites & Vectors (2023)

  20. No Access

    Article

    Conductivity characteristics of landslide considering porosity, saturation, temperature and ion concentration

    High-density resistivity imaging method is widely used in landslide monitoring. The resistivity of rock and soil is closely related to factors, such as porosity, moisture content, saturation and temperature. I...

    Bo-bo **ong, Shi-jie Yang, Bing-qin Zhao, **ao-chun Lu in Journal of Mountain Science (2023)

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