Energy Informatics
Third Energy Informatics Academy Conference, EI.A 2023, Campinas, Brazil, December 6–8, 2023, Proceedings, Part II
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Open AccessThe Shigella kinase effector OspG modulates host ubiquitin signaling to escape septin-cage entrapment
Shigella flexneri is a Gram-negative bacterium causing severe bloody dysentery. Its pathogenesis is largely dictated by a plasmid-encoded type III secretion system (T3SS) and its associated effectors. Among these...
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Article
Open AccessCirc-0075305 hinders gastric cancer stem cells by indirectly disrupting TCF4–β-catenin complex and downregulation of SOX9
CircRNAs are covalently closed, single-stranded RNA that form continuous loops and play a crucial role in the initiation and progression of tumors. Cancer stem cells (CSCs) are indispensable for cancer develop...
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Article
Combined effect of rock fabric, in-situ stress, and fluid viscosity on hydraulic fracture propagation in Chang 73 lacustrine shale from the Ordos Basin
Shale oil is an important area for the increasing of crude oil reserves and production. Due to the tight structure and ultra-low permeability of shale oil reservoir, the industrial exploitation needs large-sca...
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Creation of memory–memory entanglement in a metropolitan quantum network
Towards realizing the future quantum internet1,2, a pivotal milestone entails the transition from two-node proof-of-principle experiments conducted in laboratories to comprehensive multi-node set-ups on large sca...
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Open AccessThe relationship between social support and professional identity of health professional students from a two-way social support theory perspective: chain mediating effects of achievement motivation and meaning in life
Studies has suggested that receiving social support improves the professional identity of health professional students. According to the two-way social support theory, social support includes receiving social ...
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Article
Open AccessTBK1, a prioritized drug repurposing target for amyotrophic lateral sclerosis: evidence from druggable genome Mendelian randomization and pharmacological verification in vitro
There is a lack of effective therapeutic strategies for amyotrophic lateral sclerosis (ALS); therefore, drug repurposing might provide a rapid approach to meet the urgent need for treatment.
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Article
Role of thrombospondin-1 in high-salt–induced mesenteric artery endothelial impairment in rats
The matrix glycoprotein thrombospondin-1 (THBS1) modulates nitric oxide (NO) signaling in endothelial cells. A high-salt diet induces deficiencies of NO production and bioavailability, thereby leading to endot...
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Article
Open AccessQuality of childcare and delayed child development in left-behind children in China
Inequalities in job opportunities and income prompts many Chinese parents to leave rural regions to work in urban regions. Their children are left behind in rural regions, subjected to worse quality of childca...
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Book and Conference Proceedings
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Article
Structural characteristics and tribological properties of an ultrafine-grained Al–40Si–5Fe coating prepared by supersonic plasma spraying
High silicon aluminum alloy coatings (HSAACs) are characterized by high surface hardness and excellent wear resistance, and the fineness has a significant impact on their properties. In this study, Al–40Si–5Fe...
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Article
Open AccessAdvances in nuclear detection and readout techniques
“A Craftsman Must Sharpen His Tools to Do His Job,” said Confucius. Nuclear detection and readout techniques are the foundation of particle physics, nuclear physics, and particle astrophysics to reveal the nat...
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Open AccessIndocyanine green fluorescence imaging-guided versus conventional laparoscopic lymphadenectomy for gastric cancer: long-term outcomes of a phase 3 randomised clinical trial
Indocyanine green (ICG) fluorescence imaging-guided lymphadenectomy has been demonstrated to be effective in increasing the number of lymph nodes (LNs) retrieved in laparoscopic gastrectomy for gastric cancer ...
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Article
Open AccessExpanding causal genes for Parkinson’s disease via multi-omics analysis
Genome‑wide association studies (GWASs) have revealed numerous loci associated with Parkinson’s disease (PD). However, some potential causal/risk genes were still not revealed and no etiological therapies are ...
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Article
Open AccessPersonalized radiomics signature to screen for KIT-11 mutation genotypes among patients with gastrointestinal stromal tumors: a retrospective multicenter study
Gastrointestinal stromal tumors (GISTs) carrying different KIT exon 11 (KIT-11) mutations exhibit varying prognoses and responses to Imatinib. Herein, we aimed to determine whether computed tomography (CT) rad...
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Article
Open AccessClinical application of endobronchial ultrasonography-guided transbronchial needle aspiration biopsy—a single center, large sample, real-world study
Endobronchial ultrasonography-guided transbronchial needle aspiration biopsy (EBUS-TBNA) has been used for more than 10 years in China. Its clinical application and diagnostic value in different diseases with ...
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Article
Open AccessVascular wall microenvironment: exosomes secreted by adventitial fibroblasts induced vascular calcification
Vascular calcification often occurs in patients with chronic renal failure (CRF), which significantly increases the incidence of cardiovascular events in CRF patients. Our previous studies identified the cross...
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Article
Insight-HXMT on-orbit thermal control status and thermal deformation impact analysis
The Hard X-ray Modulation Telescope is China’s first X-ray astronomy satellite launched on June 15, 2017, dubbed Insight-HXMT. Active and passive thermal control measures are employed to keep devices at suitable ...
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Article
Naphthylisoquinoline alkaloids, a new structural template inhibitor of Nav1.7 sodium channel
Voltage-gated sodium channel 1.7 (Nav1.7) remains one of the most promising drug targets for pain relief. In the current study, we conducted a high-throughput screening of natural products in our in-house comp...
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Article
Effects of Ni content and tempering temperatures on microstructure and properties of medium-carbon cast steel
The microstructure evolution and properties of medium-carbon cast steel alloyed with different Ni contents after tempering at various temperatures have been investigated. The addition of 0.47–1.59 wt.% Ni cont...
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Article
Effect of Ce on microstructure and mechanical properties of Mg-Zn-Ce magnesium alloys
The Mg-6Zn alloy with different contents of Ce was prepared by the gravity casting method, and then the Mg-6Zn-xCe (x=0, 0.5, 1.0, 1.5, wt.%) alloys were extruded at 300 °C and 350 °C after solution treatment. Th...
