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Article
Adaptive Multi-Source Predictor for Zero-Shot Video Object Segmentation
Static and moving objects often occur in real-life videos. Most video object segmentation methods only focus on extracting and exploiting motion cues to perceive moving objects. Once faced with the frames of s...
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Article
Vagus nerve electrical stimulation in the recovery of upper limb motor functional impairment after ischemic stroke
Ischemic stroke (IS) is characterized by high mortality, disability rates, and a high risk of recurrence. Motor dysfunction, such as limb hemiparesis, dysphagia, auditory disorders, and speech disorders, usual...
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Article
Open AccessAnalysis of the aging-related biomarker in a nonhuman primate model using multilayer omics
Aging is a prominent risk factor for diverse diseases; therefore, an in-depth understanding of its physiological mechanisms is required. Nonhuman primates, which share the closest genetic relationship with hum...
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Article
Open AccessStructural basis for an early stage of the photosystem II repair cycle in Chlamydomonas reinhardtii
Photosystem II (PSII) catalyzes water oxidation and plastoquinone reduction by utilizing light energy. It is highly susceptible to photodamage under high-light conditions and the damaged PSII needs to be resto...
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Article
Seismic performance of a new type of prefabricated bridge pier with cast-in-place UHPC jacketing
Accelerated bridge construction (ABC) is prevalent all over the world attributable to its technical advantages including the higher construction efficiency, less traffic disruption, and higher construction qua...
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Article
TOPK Inhibition Enhances the Sensitivity of Colorectal Cancer Cells to Radiotherapy by Reducing the DNA Damage Response
Abnormal expression of T-lymphokine-activated killer cell-originated protein kinase (TOPK) was reported to be closely related to the resistance of prostate cancer to radiotherapy and to targeted drug resistanc...
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Article
The Gut Microbiome Affects Atherosclerosis by Regulating Reverse Cholesterol Transport
The human system’s secret organ, the gut microbiome, has received considerable attention. Emerging research has yielded substantial scientific evidence indicating that changes in gut microbial composition and ...
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Article
Application of UiO-66 and its composites for remediation and resource recovery of typical environmental contaminants: a review
UiO-66 series metal–organic framework materials (MOFs) are typical porous materials assembled by Zr4+ with a large mass-to-nucleus ratio and terephthalic acid ligands, which form tetrahedral and octahedral cages ...
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Article
Practical synthesis of tetrahydrofolate by highly efficient catalytic hydrogenation in continuous flow
Hundred-gram scale of highly selective catalytic hydrogenation of folic acid has been developed, which is adopted continuous-flow technology with Raney Ni as a catalyst. Through optimization of the reaction co...
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Article
Open AccessMild hyperthermia enhanced synergistic uric acid degradation and multiple ROS elimination for an effective acute gout therapy
Acute gouty is caused by the excessive accumulation of Monosodium Urate (MSU) crystals within various parts of the body, which leads to a deterioration of the local microenvironment. This degradation is marked...
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Article
Open AccessTargeting cathepsin S promotes activation of OLF1-BDNF/TrkB axis to enhance cognitive function
Cathepsin S (CTSS) is a cysteine protease that played diverse roles in immunity, tumor metastasis, aging and other pathological alterations. At the cellular level, increased CTSS levels have been associated wi...
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Article
Vascular smooth muscle-specific LRRC8A knockout ameliorates angiotensin II-induced cerebrovascular remodeling by inhibiting the WNK1/FOXO3a/MMP signaling pathway
Hypertensive cerebrovascular remodeling involves the enlargement of vascular smooth muscle cells (VSMCs), which activates volume-regulated Cl− channels (VRCCs). The leucine-rich repeat-containing family 8 A (LRRC...
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Article
Open AccessHepatic artery infusion chemotherapy combined with camrelizumab plus rivoceranib for hepatocellular carcinoma with portal vein tumor thrombosis: a multicenter propensity score-matching analysis
Portal vein tumor thrombosis (PVTT) signifies late-stage hepatocellular carcinoma (HCC) with high-risk progression and poor prognosis. As a standard treatment, sorafenib monotherapy has limited the efficacy in...
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Article
Towards Diverse Binary Segmentation via a Simple yet General Gated Network
In many binary segmentation tasks, most CNNs-based methods use a U-shape encoder-decoder network as their basic structure. They ignore two key problems when the encoder exchanges information with the decoder: ...
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Article
Open AccessA novel long non-coding RNA MIR4500HG003 promotes tumor metastasis through miR-483-3p-MMP9 axis in triple-negative breast cancer
Breast cancer (BC) is the most common cancer and the leading cause of cancer-related deaths in women worldwide. The 5-year survival rate is over 90% in BC patients, but once BC cells metastasis into distal org...
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Article
Thermally Conductive, Healable Glass Fiber Cloth Reinforced Polymer Composite based on β-Hydroxyester Bonds Crosslinked Epoxy with Improved Heat Resistance
To simultaneously endow thermal conductivity, high glass transition temperature (Tg) and healing capability to glass fiber/epoxy (GFREP) composite, dynamic crosslinked epoxy resin bearing reversible β-hydroxyl es...
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Article
RNA m6A methylation and regulatory proteins in pulmonary arterial hypertension
m6A (N6‑methyladenosine) is the most common and abundant apparent modification in mRNA of eukaryotes. The modification of m6A is regulated dynamically and reversibly by methyltransferase (writer), demethylase ...
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Article
Effects of dietary supplements, foods, and dietary patterns in Parkinson’s disease: meta-analysis and systematic review of randomized and crossover studies
Diet significantly impacts Parkinson’s disease (PD) with plausible biological hypotheses. Although the thesis has been explored in several human clinical trials, no current meta-analyses or reviews summarize t...
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Article
Impact of age and anterior fibromuscular stroma preservation on post-enucleation voided volume
This study is centered on the critical role of anterior fibromuscular stroma (AFS) preservation in prostate enucleation, an emerging strategy aimed at minimizing postoperative urinary incontinence—a common con...
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Article
Open AccessRadical innovation breakthroughs of biodegradation of plastics by insects: history, present and future perspectives
Insects damaging and penetrating plastic packaged materials has been reported since the 1950s. Radical innovation breakthroughs of plastic biodegradation have been initiated since the discovery of biodegradati...
