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  1. No Access

    Chapter and Conference Paper

    Evaluation of E-Cadherins in Growth Patterns of Gastric Cancer and Its Degree of Cell Differentiation

    The growth pattern in gastric cancer (GC) classified into expanding and infiltrative type proposed by professor Ming. This study examined the expression of E-Cadherins (E-Cad), an intercellular adhesion molecu...

    Zhi-** Chen, Jian-Chun Chai in Recent Advances in Management of Digestive… (1993)

  2. No Access

    Chapter and Conference Paper

    MMC-CH40 Staining the Regional Lymphnodes in the Use of Radical Operation for Gastric Cancer

    In the present study, 1-2 ml MMC-CH40 have been injected directly into the lymphnodes (LNs) around the cancer during the operation, LN clearing number (23±11 LNs/case) was 1.13 times higher after the injection co...

    Gu-**ang Ye, **n-Chang Jiang, Wei-Que Lu in Recent Advances in Management of Digestive… (1993)

  3. No Access

    Article

    mRNA levels of nm23 in murine ascites hepatoma (H22) clones with different lymphatic metastatic potential

    Levels of expression of the nm23 gene inversely correlated with metastatic potential in several rodent tumor model systems and human breast carcinoma. In the present study, we examined nm23 mRNA levels in two ...

    **an-Peng Jiang, Zhao-You Tang, Kang-Da Liu in Journal of Cancer Research and Clinical On… (1996)

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    Article

    Elevated activity of N -acetylglucosaminyltransferase V in human hepatocellular carcinoma

    Cell-surface glycoproteins are regarded as candidates for involvement in the spread of tumor cells. N-linked β1-6 branched oligosaccharides may contribute directly to the malignant or metastatic phenotypes of...

    Min Yao, Da-Peng Zhou, Shong-Min Jiang in Journal of Cancer Research and Clinical On… (1998)

  5. No Access

    Article

    Human papillomavirus,Chlamydia trachomatis, and other risk factors associated with cervical cancer in China

    High prevalences of human papillomavirus (HPV) andChlamydia trachomatis infections, and their association with cervical cancer, have been reported in some parts of China. Other factors, including pregnancy and sm...

    Yu-zhen Dong, Toshiyuki Sasagawa in International Journal of Clinical Oncology (1998)

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    Article

    Evaluation of in vitro chemosensitivity of antitumor drugs using the MTT assay in fresh human breast cancer

    Practical criteria were developed in this paper for the purpose of evaluating chemosensitivity of fresh human breast cancer by the MTT assay. The survival rates at maximum inhibition (Imax %) and the concentra...

    Jian-Ming Xu, San-Tai Song, Zhong-Ming Tang in Breast Cancer Research and Treatment (1998)

  7. No Access

    Article

    Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis

    To develop an in vivo model for studying the role of the p53 tumor suppressor in skin carcinogenesis, a murine p53172H mutant (equivalent to human p53175H) was expressed in the epidermis of transgenic mice, utili...

    **ao-**g Wang, David A Greenhalgh, Aibo Jiang, Dacheng He, Ling Zhong in Oncogene (1998)

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    Article

    Predictive chemotherapy of advanced breast cancer directed by MTT assay in vitro

    In order to investigate the predictive value of in vitro MTT assay for directing chemotherapy of breast cancer patients, from 1992 to 1995, 156 advanced breast cancer patients who had evaluable lesions were re...

    Jian‐ming Xu, San‐tai Song, Zhong‐ming Tang in Breast Cancer Research and Treatment (1999)

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    Chapter

    Polyunsaturated Fatty Acids and Their Role in Cancer Invasion and Metastasis

    Highly unsaturated fatty acids (HUFAs) have been demonstrated to have anticancer functions in the past decade. Recently, these fatty acids have been shown to exert a regulatory action on tumour cell motility, ...

    Wen G Jiang, Amanda Redfern, Aldo Eynard in Cancer Metastasis, Molecular and Cellular … (2000)

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    Article

    Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer

    We previously demonstrated that AKT2, a member of protein kinase B family, is activated by a number of growth factors via Ras and PI 3-kinase signaling pathways. Here, we report the frequent activation of AKT2...

    Zeng Qiang Yuan, Mei Sun, Richard I Feldman, Gen Wang, **ao-ling Ma, Chen Jiang in Oncogene (2000)

  11. No Access

    Article

    Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties

    Abnormalities in cellular differentiation are frequent occurrences in human cancers. Treatment of human melanoma cells with recombinant fibroblast interferon (IFN-β) and the protein kinase C activator mezerein...

    Eric Y Huang, Malavi T Madireddi, Rahul V Gopalkrishnan in Oncogene (2001)

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    Article

    Functional p53 is required for triptolide-induced apoptosis and AP-1 and nuclear factor-κB activation in gastric cancer cells

    Triptolide, a major component in the extract of Chinese herbal plant Tripterygium wilfordii Hook f (TWHf), has potential anti-neoplastic effect. In the present study we investigated the potential therapeutic e...

    **ao-Hua Jiang, Benjamin Chun-Yu Wong, Marie Chia-Mi Lin, Geng-Hui Zhu in Oncogene (2001)

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    Article

    Novel target for induction of apoptosis by cyclo-oxygenase-2 inhibitor SC-236 through a protein kinase C-β1-dependent pathway

    Nonsteroidal anti-inflammatory drugs (NSAIDs) reduce the risk of gastrointestinal cancers. Recently, a similar protective effect has been demonstrated by the specific cyclo-oxygenase-2 (COX-2) inhibitors. Howe...

    **ao-Hua Jiang, Shiu-Kum Lam, Marie CM Lin, Shi-Hu Jiang, Hsiang-Fu Kung in Oncogene (2002)

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    Article

    Comparison between radioimmunotherapy and external beam radiation therapy for patients with hepatocellular carcinoma

    It has previously been observed in animal studies that, at equivalent doses, radioimmunotherapy (RIT) is 2.5 times more effective than multiple fractions of external beam radiation therapy (EBRT) in inhibitin...

    Zhao-Chong Zeng, Zhao-You Tang in European Journal of Nuclear Medicine and M… (2002)

  15. No Access

    Article

    Profiling genes differentially expressed in NGX6 overexpressed nasopharyngeal carcinoma cells by cDNA array

    Abstract

    Jian Ma, Jiang Li, Jie Zhou, **ao-Ling Li in Journal of Cancer Research and Clinical On… (2002)

  16. Article

    Open Access

    RARRES3 expression positively correlated to tumour differentiation in tissues of colorectal adenocarcinoma

    RARRES3 is a retinoid-inducible class II tumour-suppressor gene. This study analysed the expression of RARRES3 protein in normal, adenoma and carcinoma tissues of the colorectum and its correlation with tumour di...

    R-Y Shyu, S-Y Jiang, J-M Chou, Y-L Shih, M-S Lee, J-C Yu in British Journal of Cancer (2003)

  17. No Access

    Article

    Antisense Tcf inhibits the neoplastic growth of liver cancer cells

     T cell transcription factors are nuclear effectors of the Wnt signaling transduction pathway and play crucial roles in embryonic and malignant development. Our previous study showed increased expression level...

    Ying Jiang, **n-Da Zhou, Yin-Kun Liu in Journal of Cancer Research and Clinical On… (2004)

  18. No Access

    Article

    Sensitization of multiple myeloma and B lymphoma lines to dexamethasone and γ-radiation-induced apoptosis by CD40 activation

    We examined the effects of CD40 activation with dexamethasone (Dex) or 60Co-γ-irradiation on the growth of malignant B cells in vitro, using the human multiple myeloma (MM) cell line, XG2, and the B lymphoma Daud...

    Zhao-Hua Zhou, Z-H. Zhou, Q. Shi, Qin Shi, Jiang-Fang Wang, Yong- **g Chen in Apoptosis (2005)

  19. No Access

    Article

    Association between clinical characteristics and expression abundance of RTKN gene in human bladder carcinoma tissues from Chinese patients

    Bladder carcinoma is the most common urological malignancy in China. Gene mutation may be one of causes of carcinogenesis in the cancer. We therefore investigated the mRNA expression of RTKN gene in clinic malign...

    Jie Fan, Li-Jie Ma, Shu-Jie **a, Long Yu in Journal of Cancer Research and Clinical On… (2005)

  20. No Access

    Article

    Clinical analysis of microdebrider removal of recurrent respiratory papilloma: A report of 33 cases

    OBJECTIVE To investigate the advantages of applying microdebrider removal of juvenile-onset recurrent respiratory papillary epithelioma (JO-RRP), using an endoscopy-assisted prop-up laryngoscope.

    Wenbin Lei, Zhenzhong Su, Wei** Wen, Li** Chai in Chinese Journal of Clinical Oncology (2006)

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