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Transcription factor Dp-1 knockdown downregulates thymidine kinase 1 expression to protect against proliferation and epithelial-mesenchymal transition in cervical cancer
Thymidine kinase 1 (TK1) level is an independent survival prognostic factor for both premalignant and malignant cervical pathologies. Herein, this study sought to probe the impacts of TK1 on cervical cancer (C...
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Article
Behavioral adaptation in an adoptive free-ranging female Tibetan macaque
Adoption is an important form of allomaternal care in nonhuman primates, with implications for reproductive output and infant survival. Here, we report a kidnap** that became an adoption of a 3-week-old infa...
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Article
Genome-wide Transcriptome Analysis Reveals the Gene Regulatory Network in Star Fruit Flower Blooming
The star fruit is a perennial woody fruit tree, which can blossom and bear fruit many times a year. The time and quantity of flowering are the key indicators of its economic value. However, the flowering molec...
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Article
Open AccessChloroplast genome characteristics and phylogeny of the sinodielsia clade (apiaceae: apioideae)
The Sinodielsia clade of the subfamily Apioideae (Apiacieae) was established in 2008, and it is composed of 37 species from 17 genera. Its circumscription is still poorly delimited and unstable, and interspecific...
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Article
Transformation of Human Umbilical Vein Endothelial Cells Induced by the Tumor Microenvironment of Nephroblastoma Cells
Nephroblastoma is one of the most common renal malignancies in children, and tumor angiogenesis increases the risk of metastasis and recurrence. This study investigated the effect of the tumor microenvironment...
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Open AccessCorrection: Cinnamtannin A2 protects the renal injury by attenuates the altered expression of kidney injury molecule 1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL) expression in 5/6 nephrectomized rat model
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Transcriptome and Proteins Analysis Reveals the Gene Regulatory Processes Mediated by LaAP2L1, an AP2/ERF Transcription Factor, Functioning in Fast-Growing Heterosis in Larix kaempferi
Larix is an important commercial tree species and possesses huge value in ecological protection. Heterosis is a common genetic phenomenon in Larix, and it has been widely used to breed new varieties with fast-gro...
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Article
Open AccessAnalysis of Whole Blood and Urine Trace Elements in Children with Autism Spectrum Disorders and Autistic Behaviors
The relationship between trace elements and neurological development is an emerging research focus. We performed a case–control study to explore (1) the differences of 13 trace elements chromium (Cr), manganes...
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Update on Regulation of Regenerative Medicine in Taiwan
Due to rapid development of biotechnology in recent years, the field of regenerative medicine has attracted considerable attention. Regenerative medicine–related regulations have been established in several co...
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The Conclusion: How to End a Scientific Report in Style
Sometimes students have the mistaken belief that the conclusion of a scientific report is just a perfunctory ending that repeats what was presented in the main sections of the report. However, impactful conclu...
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Article
Correction to: Phomopsis liquidambaris reduces ethylene biosynthesis in rice under salt stress via increasing the activity of 1-aminocyclopropane-1-carboxylate deaminase
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Article
Open AccessmicroRNA-124-3p attenuates myocardial injury in sepsis via modulating SP1/HDAC4/HIF-1α axis
Sepsis-induced cardiac dysfunction can lead to death in sepsis. In this case, we targeted to explore in detail the relative mechanism of microRNA (miR)-124-3p in sepsis-induced myocardial injury via the specif...
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Article
Phomopsis liquidambaris reduces ethylene biosynthesis in rice under salt stress via inhibiting the activity of 1-aminocyclopropane-1-carboxylate deaminase
The endophytic fungus Phomopsis liquidambaris is characterized as a plant growth-promoting agent under salt stress, but its mechanism is unknown. Herein, 1-aminocyclopropane-1-carboxylate deaminase (ACCD) from th...
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Open AccessThe spliceosome factor sart3 regulates hematopoietic stem/progenitor cell development in zebrafish through the p53 pathway
Hematopoietic stem cells (HSCs) possess the potential for self-renew and the capacity, throughout life, to differentiate into all blood cell lineages. Yet, the mechanistic basis for HSC development remains lar...
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The disruption of the MAPKK gene triggering the synthesis of flavonoids in endophytic fungus Phomopsis liquidambaris
Flavonoids, which are mainly extracted from plants, are important antioxidants and play an important role in human diseases. However, the growing market demand is limited by low productivity and complex produc...
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Article
Open AccessCinnamtannin A2 protects the renal injury by attenuates the altered expression of kidney injury molecule 1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL) expression in 5/6 nephrectomized rat model
Present investigation determines the protective effect of Cinnamtannin A2 against chronic renal failure (CRF). 5/6 nephrectomized rat model was used to induced CRF by removing the kidneys and rats were treated...
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Article
Open AccessAlkaloid Constituents of Ficus hispida and Their Antiinflammatory Activity
Four new alkaloids, ficuhismines A–D (1–4), together with three known ones, were isolated from Ficus hispida. Their structures were elucidated by spectroscopic analysis and chemical method. The new compounds repr...
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Article
Open AccessMesenchymal stem cells alleviate liver injury induced by chronic-binge ethanol feeding in mice via release of TSG6 and suppression of STAT3 activation
Mesenchymal stem cells (MSCs) are a population of pluripotent cells that might be used for treatment of liver disease. However, the efficacy of MSCs for mice with alcoholic hepatitis (AH) and its underlying me...
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Article
Two new Neofomitella species (Polyporaceae, Basidiomycota) based on morphological and molecular evidence
Two new Neofomitella species, N. australiensis and N. guangxiensis, are described based on morphological and molecular characters. Neofomitella australiensis is characterized by white pore surface when fresh, dex...
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Open AccessRegulation of the small GTPase Rab1 function by a bacterial glucosyltransferase
Posttranslational modification of key host proteins by virulence factors is an important theme in bacterial pathogenesis. A remarkable example is the reversible modifications of the small GTPase Rab1 by multip...