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  1. No Access

    Article

    Diclofenac sex-divergent drug-drug interaction with Sunitinib: pharmacokinetics and tissue distribution in male and female mice

    Coadministration of diclofenac and sunitinib, tyrosine kinase inhibitor, led to sex-divergent pharmacokinetic drug-drug interaction outcomes. Male and female mice were administered 60 mg/kg PO sunitinib alone ...

    Chii Chii Chew, Salby Ng, Yun Lee Chee, Teng Wai Koo… in Investigational New Drugs (2017)

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    Article

    Sunitinib-paracetamol sex-divergent pharmacokinetics and tissue distribution drug-drug interaction in mice

    The sex-divergent pharmacokinetics and interaction of tyrosine kinase inhibitor sunitinib with paracetamol was evaluated in male and female mice. Mice (control groups) were administered 60 mg/kg PO sunitinib a...

    Ming Hui Liew, Salby Ng, Chii Chii Chew, Teng Wai Koo… in Investigational New Drugs (2017)