101 Result(s)

Article

Neutrophil-derived migrasomes are an essential part of the coagulation system

Migrasomes are organelles that are generated by migrating cells. Here we report the key role of neutrophil-derived migrasomes in haemostasis. We found that a large number of neutrophil-derived migrasomes exist...

Dong Jiang, Lin Jiao, Qing Li, Renxiang **e, Haohao Jia, ShiHui Wang… in Nature Cell Biology (2024)

Article

Diabetes and aortic dissection: unraveling the role of 3-hydroxybutyrate through mendelian randomization

In observational and experimental studies, diabetes has been reported as a protective factor for aortic dissection. 3-Hydroxybutyrate, a key constituent of ketone bodies, has been found to favor improvements i...

Shi Qiu, Zhen Liu, Wei-Dong Jiang, **-Hui Sun… in Cardiovascular Diabetology (2024)

Article

Genetic fusion of CCL11 to antigens enhances antigenicity in nucleic acid vaccines and eradicates tumor mass through optimizing T-cell response

Nucleic acid vaccines have shown promising potency and efficacy for cancer treatment with robust and specific T-cell responses. Improving the immunogenicity of delivered antigens helps to extend therapeutic ef...

Hailong Qi, Zhongjie Sun, Tianle Gao, Yanling Yao, Yu Wang, Weiwei Li… in Molecular Cancer (2024)

Article

Correction: Single-cell profiling reveals the trajectory of FOLR2-expressing tumor-associated macrophages to regulatory T cells in the progression of lung adenocarcinoma

Chan **ang, Min Zhang, Zhanxian Shang, Shengnan Chen, Jikai Zhao… in Cell Death & Disease (2024)

Article

Circ_0000376 regulates miR-577/HK2/LDHA signaling pathway to promote the growth, invasion and glycolysis of osteosarcoma

Many studies have confirmed that circular RNAs (circRNAs) mediate the malignant progression of various tumors including osteosarcoma (OS). Our study is to uncover novel molecular mechanisms by which circ_00003...

Hongchun Dai, Guangming Yi, Dong Jiang… in Journal of Orthopaedic Surgery and Research (2024)

Article

Experimental sensing quantum atmosphere of a single spin

Understanding symmetry-breaking states of materials is a major challenge in the modern physical sciences. Quantum atmosphere proposed recently sheds light on the hidden world of these symmetry broken patterns....

Kehang Zhu, Zhi** Yang, Qing-Dong Jiang, Zihua Chai, Zhijie Li… in Quantum Frontiers (2024)

Article

Human apical-out nasal organoids reveal an essential role of matrix metalloproteinases in airway epithelial differentiation

Extracellular matrix (ECM) assembly/disassembly is a critical regulator for airway epithelial development and remodeling. Airway organoid is widely used in respiratory research, yet there is limited study to i...

Liyue Li, Linyi Jiao, Danni Feng, Yizhang Yuan, **aoqian Yang… in Nature Communications (2024)

Article

Macro-superlubricity in sputtered MoS₂-based films by decreasing edge pinning effect

To date, MoS₂ can only be achieved at microscale. Edge pinning effect caused by structure defects is the most obvious barrier to expand the size of structural superlubricity to macroscale. Herein, we plan to pin ...

Chunmeng Dong, Dong Jiang, Yanlong Fu, Desheng Wang, Qinqin Wang, Lijun Weng… in Friction (2024)

Article

Oncological prognosis and morbidity of hepatectomy in elderly patients with hepatocellular carcinoma: a propensity score matching and multicentre study

With increasing life expectancy, the number of elderly patients (≥ 65 years) with hepatocellular carcinoma (HCC) has steadily increased. Hepatectomy remains the first-line treatment for HCC patients. However, ...

Chuan-Ming Wang, Zi-**ang Chen, **-Chuan Ma, Jiang-Ming Chen, Dong Jiang… in BMC Surgery (2023)

Article

SCARB2 drives hepatocellular carcinoma tumor initiating cells via enhanced MYC transcriptional activity

CSCs (Cancer stem cells) with distinct metabolic features are considered to cause HCC (hepatocellular carcinoma) initiation, metastasis and therapeutic resistance. Here, we perform a metabolic gene CRISPR/Cas9...

Feng Wang, Yang Gao, Situ Xue, Luyao Zhao, Huimin Jiang… in Nature Communications (2023)

Article

Z-ligustilide preferentially caused mitochondrial dysfunction in AML HL-60 cells by activating nuclear receptors NUR77 and NOR1

Nuclear receptors NUR77 and NOR1 were identified as critical targets in acute myeloid leukemia (AML) therapy. Previously, we showed that Z-ligustilide (Z-LIG) selectively targeted AML by restoring NUR77 and NO...

Gen Liu, Zhi-gang Chen, Li-rong Yang, Yu-xia Rong, Qin Wang, Li Li… in Chinese Medicine (2023)

Article

The implications for potential marginal land resources of cassava across worldwide under climate change challenges

The demand for energy plants is foreseen to grow as worldwide energy and climate policies promote the use of bioenergy for climate change mitigation. To avoid competing with food production, it’s critical to a...

Yong** Li, Fangyu Ding, Mengmeng Hao, Shuai Chen, Dong Jiang… in Scientific Reports (2023)

Article

Spatial–temporal distribution of global production–living–ecological space during the period 2000–2020

Global production-living-ecology space closely corresponds with sustainable development’s economic, social and ecological elements. The dataset of global production–living–ecological space in this paper was ge...

**gying Fu, Qiang Gao, Dong Jiang, **ang Li, Gang Lin in Scientific Data (2023)

Article

Quantifying the influence of climate variability on armed conflict in Africa, 2000–2015

Global climate change, expected to be one of the most severe challenges that human beings have ever encountered, has had far-reaching impacts on ecosystems and humans, among which the potentially increasing ch...

Qian Wang, Mengmeng Hao, David Helman… in Environment, Development and Sustainability (2023)

Article

Single-cell profiling reveals the trajectory of FOLR2-expressing tumor-associated macrophages to regulatory T cells in the progression of lung adenocarcinoma

An immunosuppressive microenvironment enriched with regulatory CD4⁺ T lymphocytes (Tregs) facilitates the progression of lung adenocarcinoma (LUAD). This study aims to investigate the cellular mechanism underlyin...

Chan **ang, Min Zhang, Zhanxian Shang, Shengnan Chen, Jikai Zhao… in Cell Death & Disease (2023)

Article

Anthropogenic modifications: impacts and conservation strategies

Andrea Belgrano, Federica Cucchiella, Dong Jiang, Marianna Rotilio in Scientific Reports (2023)

Article

Epidemiological characteristics and risk factors for cystic and alveolar echinococcosis in China: an analysis of a national population-based field survey

Human cystic and alveolar echinococcosis are neglected tropical diseases that WHO has prioritized for control in recent years. Both diseases impose substantial burdens on public health and the socio-economy in...

Tian Ma, Qian Wang, Mengmeng Hao, Chuizhao Xue, Xu Wang, Shuai Han… in Parasites & Vectors (2023)

Article

Memory-dictated dynamics of single-atom Pt on CeO₂ for CO oxidation

Single atoms of platinum group metals on CeO₂ represent a potential approach to lower precious metal requirements for automobile exhaust treatment catalysts. Here we show the dynamic evolution of two types of sin...

Zihao Zhang, **shu Tian, Yubing Lu, Shize Yang, Dong Jiang… in Nature Communications (2023)

Article

Field-measured canopy height may not be as accurate and heritable as believed: evidence from advanced 3D sensing

Canopy height (CH) is an important trait for crop breeding and production. The rapid development of 3D sensing technologies shed new light on high-throughput height measurement. However, a systematic compariso...

**grong Zang, Shichao **, Songyin Zhang, Qing Li, Yue Mu, Ziyu Li… in Plant Methods (2023)

Article

Exploring the global geography of cybercrime and its driving forces

Cybercrime is wreaking havoc on the global economy, national security, social stability, and individual interests. The current efforts to mitigate cybercrime threats are primarily focused on technical measures...

Shuai Chen, Mengmeng Hao, Fangyu Ding… in Humanities and Social Sciences Communicati… (2023)