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  1. No Access

    Article

    Mammalian IRE1α dynamically and functionally coalesces with stress granules

    Upon endoplasmic reticulum (ER) stress, activation of the ER-resident transmembrane protein kinase/endoribonuclease inositol-requiring enzyme 1 (IRE1) initiates a key branch of the unfolded protein response (U...

    Songzi Liu, **aoge Zhang, **n Yao, Guan Wang, Shijia Huang… in Nature Cell Biology (2024)

  2. Article

    Targeted capture enrichment and sequencing identifies HLA variants associated with the severity of COVID-19

    Coronavirus disease 2019 (COVID-19) is currently a global pandemic. The pathogenesis of severe COVID-19 has been widely investigated, but it is still unclear. Human leukocyte antigen (HLA) plays a central role...

    Chuanmiao Liu, Li Zhang, Jiasheng Chen, Yu Gao in Genes & Genomics (2023)

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  3. No Access

    Article

    Adipocyte IRE1α promotes PGC1α mRNA decay and restrains adaptive thermogenesis

    Adipose tissue undergoes thermogenic remodeling in response to thermal stress and metabolic cues, playing a crucial role in regulating energy expenditure and metabolic homeostasis. Endoplasmic reticulum (ER) s...

    Yong Chen, Zhuyin Wu, Shijia Huang, **aoxia Wang, Sijia He, Lin Liu… in Nature Metabolism (2022)

  4. No Access

    Article

    Association between STAT4 polymorphisms and risk of primary biliary cholangitis: a meta-analysis

    Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease. Several studies reported that SATA4 (signal transducer and activator of transcription 4) polymorphisms were significantly associated wit...

    Li Zhang, Chunming Gao, Chuanmiao Liu, Jiasheng Chen, Kuihua Xu in Genes & Genomics (2018)

  5. Article

    Inhibition of neddylation by MLN4924 improves neointimal hyperplasia and promotes apoptosis of vascular smooth muscle cells through p53 and p62

    Targeting apoptosis of vascular smooth muscle cells (VSMCs) represents an attractive approach to diminish the occurrence of restenosis. Neddylation is a highly conserved post-translational modification process...

    Tang-Jun Ai, Jian-Yong Sun, Lin-Juan Du, Chaoji Shi… in Cell Death & Differentiation (2018)

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  6. No Access

    Article

    Microsatellite records for volume 9, issue 3

    Aiguo Yang, Biao Wu, Chao Shen, Guangming Zhang… in Conservation Genetics Resources (2017)

  7. Article

    Flexural creep behavior of bamboo culm (Phyllostachys pubescens) in its radial direction

    As a construction material, the phenomenon of creep is critical to bamboo structural design. The present work investigates variation of flexural creep behavior of bamboo (Phyllostachys pubescens) in its radial di...

    **nxin Ma, **anmiao Liu, Zehui Jiang, Benhua Fei, Ge Wang in Journal of Wood Science (2016)

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  8. No Access

    Article

    Association between PNPLA3 rs738409 polymorphism and hepatocellular carcinoma risk: an updated meta-analysis

    Hepatocellular carcinoma (HCC) is a common malignant tumor and the leading cause of cancer-related death worldwide. The protein encoded by patatin-like phospholipase domain-containing protein 3 (PNPLA3) plays imp...

    Li Zhang, Chuanmiao Liu, Kuihua Xu, Jiasheng Chen in Genes & Genomics (2016)