-
Article
Open AccessEfficacy of PE-PLIF with a novel ULBD approach for lumbar degeneration diseases: a large-channel endoscopic retrospective study
This study aims to assess the effectiveness of Percutaneous Endoscopic Posterior Lumbar Interbody Fusion (PE-PLIF) combined with a novel Unilateral Laminotomy for Bilateral Decompression (ULBD) approach using ...
-
Article
Open AccessThe dysregulation of biliary tract microflora is closely related to primary choledocholithiasis: a multicenter study
Bile microecology changes play an important role in the occurrence and development of choledocholithiasis. At present, there is no clear report on the difference of bile microecology between asymptomatic patie...
-
Article
Open AccessThe efficacy and safety of ultrasonic bone scalpel for removing retrovertebral osteophytes in anterior cervical discectomy and fusion: A retrospective study
In this study, we present a novel surgical method that utilizes the ultrasonic bone scalpel (UBS) for the removal of large retrovertebral osteophytes in anterior cervical discectomy and fusion (ACDF) and evalu...
-
Article
Open AccessA natural biological adhesive from snail mucus for wound repair
The discovery of natural adhesion phenomena and mechanisms has advanced the development of a new generation of tissue adhesives in recent decades. In this study, we develop a natural biological adhesive from s...
-
Article
Open AccessAn on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography
Serial femtosecond crystallography has opened up many new opportunities in structural biology. In recent years, several approaches employing light-inducible systems have emerged to enable time-resolved experim...
-
Article
Open AccessIdentification of an immune gene signature for predicting the prognosis of patients with uterine corpus endometrial carcinoma
Uterine corpus endometrial carcinoma (UCEC) is a frequent gynecological malignancy with a poor prognosis particularly at an advanced stage. Herein, this study aims to construct prognostic markers of UCEC based...
-
Article
Open AccessEUS in the diagnosis of pathologically undiagnosed esophageal tuberculosis
Esophageal tuberculosis (ET) is relatively rare, and the diagnosis is challenging. The aim of this study was to evaluate the clinical features of ET and highlight the role of endoscopic ultrasonography (EUS) i...
-
Article
Open AccessNR1D1 modulates synovial inflammation and bone destruction in rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial hyperplasia, pannus formation, and cartilage and bone destruction. Nuclear receptor subfamily 1 group D member 1 (NR1D1) func...
-
Article
Open AccessWhat does fluorine do to a protein? Thermodynamic, and highly-resolved structural insights into fluorine-labelled variants of the cold shock protein
Fluorine labelling represents one promising approach to study proteins in their native environment due to efficient suppressing of background signals. Here, we systematically probe inherent thermodynamic and s...
-
Article
Open AccessGastric tuberculosis mimicking submucosal tumor: a case series
Gastric tuberculosis mimicking submucosal tumors is extremely rare and often misdiagnosed.
-
Article
Open AccessdbMDEGA: a database for meta-analysis of differentially expressed genes in autism spectrum disorder
Autism spectrum disorders (ASD) are hereditary, heterogeneous and biologically complex neurodevelopmental disorders. Individual studies on gene expression in ASD cannot provide clear consensus conclusions. The...
-
Article
Open AccessN-Hydroxyphthalimide exhibits antitumor activity by suppressing mTOR signaling pathway in BT-20 and LoVo cells
N-Hydroxyphthalimide (NHPI), an important chemical raw material, was found to have potent and selective anti-proliferative effect on human breast carcinoma BT-20 cells, human colon ade...
