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Open AccessGenetic alterations and allele frequency of BRAF V600E and TERT mutation in papillary thyroid carcinoma with intermediate-to-high recurrence risk: a retrospective study
The predictive value of allele frequency (AF) of BRAF V600E and TERT mutations in papillary thyroid carcinoma (PTC) remains controversial. We aimed to investigate the AF of BRAF V600E and TERT mutations in interm...
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Article
Two-stage generative adversarial networks for metal artifact reduction and visualization in ablation therapy of liver tumors
The strong metal artifacts produced by the electrode needle cause poor image quality, thus preventing physicians from observing the surgical situation during the puncture process. To address this issue, we pro...
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Article
Open AccessExpression of TXLNA in brain gliomas and its clinical significance: a bioinformatics analysis
To analyze the expression of TXLNA in brain gliomas and its clinical significance.
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Real-Time Navigation with Guide Template for Pedicle Screw Placement Using an Augmented Reality Head-Mounted Device: A Proof-of-Concept Study
This study aims to explore the real-time navigation with guide template using an augmented reality head-mounted device (ARHMD) for pedicle screw placement.
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Article
Morphometric change in intervertebral foramen after percutaneous endoscopic lumbar foraminotomy: an in vivo radiographic study based on three-dimensional foramen reconstruction
This study aimed to perform in vivo three-dimensional (3D) quantitative measurements of morphometric changes in the foramen in patients with lumbar foraminal stenosis (LFS) undergoing percutaneous endoscopic l...
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Open AccessA self-efficacy-enhancing physical activity intervention in women with high-risk factors for gestational diabetes mellitus: study protocol for a randomized clinical trial
Gestational diabetes mellitus (GDM) is one of the most common medical disorders in pregnancy. Evidence has demonstrated that moderate-intensity physical activity may reduce the risk of gestational diabetes. Ho...
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Article
B7 homolog 3 induces lung metastasis of breast cancer through Raf/MEK/ERK axis
The essential action of B7 homolog 3 (B7-H3) in different diseases and cancers has been documented. We here focused on its role in breast cancer through the Raf/MEK/ERK axis regarding lung metastasis.
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Article
Open AccessNew biomarker: the gene HLA-DRA associated with low-grade glioma prognosis
Low-grade gliomas (LGG) are WHO grade II tumors presenting as the most common primary malignant brain tumors in adults. Currently, LGG treatment involves either or a combination of surgery, radiation therapy, ...
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Article
Open AccessEffectiveness of renal denervation in the treatment of hypertension: a literature review
Catheter-based renal denervation has been studied as a potential therapeutic option to reduce high blood pressure (BP). Preclinical studies in some experimental models have demonstrated an antihypertensive eff...
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Article
A convenient and stable vertebrae instance segmentation method for transforaminal endoscopic surgery planning
Transforaminal endoscopic surgery (TES) is effective for treatment of intervertebral disc-related diseases. To avoid injury to the critical structures, preoperative planning is required to find a safe working ...
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Article
Open AccessHaemorrhagic retroperitoneal paraganglioma initially manifesting as acute abdomen: a rare case report and literature review
Paragangliomas (PGLs) are extremely rare neuroendocrine tumours arising from extra-adrenal chromaffin cells. PGLs are clinically rare, difficult to diagnose and usually require surgical intervention. PGLs most...
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Article
Multiple objective planning for thermal ablation of liver tumors
Preoperative treatment planning is key to ensure successful thermal ablation of liver tumors. The planning aims to minimize the number of electrodes required for complete ablation and the damage to the surroun...
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Article
Open AccessDesign of a robot-assisted system for transforaminal percutaneous endoscopic lumbar surgeries: study protocol
Transforaminal percutaneous endoscopic lumbar surgeries (PELS) for lumbar disc herniation and spinal stenosis are growing in popularity. However, there are some problems in the establishment of the working cha...
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Open AccessThe combination of Radix Astragali and Radix Angelicae Sinensis attenuates the IFN-γ-induced immune destruction of hematopoiesis in bone marrow cells
Radix Astragali and Radix Angelicae Sinensis are two herbs that compose Danggui Buxue Tang (an herbal formula for treatment of anemia diseases). In this study, we explored the molecular mechanism and effective ta...
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Article
A “eye-in-body” integrated surgery robot system for stereotactic surgery
Current stereotactic surgical robots system relies on cumbersome operations such as calibration, tracking and registration to establish the accurate intraoperative coordinate transformation chain, which makes ...
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Article
Prostaglandin E2/EP2 receptor signalling pathway promotes diabetic retinopathy in a rat model of diabetes
Diabetic retinopathy is a common microvascular complication of diabetes mellitus and is initiated by inflammation and apoptosis-associated retinal endothelial cell damage. Prostaglandin E2 (PGE2) has emerged as a...
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Article
Robust extraction for low-contrast liver tumors using modified adaptive likelihood estimation
Liver tumor extraction is essential for liver ablation surgery planning and treatment. For accurate and robust tumor segmentation, we propose a semiautomatic method using adaptive likelihood classification wit...
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Article
An X-ray-free method to accurately identify the elbow flexion–extension axis for the placement of a hinged external fixator
Identifying the elbow flexion–extension (F–E) movement axis is important for placing a hinged elbow external fixator. An X-ray fluoroscopy-based method is widely used in clinical practice, exposing the patient...
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Article
An automatic markerless registration method for neurosurgical robotics based on an optical camera
Current markerless registration methods for neurosurgical robotics use the facial surface to match the robot space with the image space, and acquisition of the facial surface usually requires manual interactio...
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A surgical robot with augmented reality visualization for stereoelectroencephalography electrode implantation
Using existing stereoelectroencephalography (SEEG) electrode implantation surgical robot systems, it is difficult to intuitively validate registration accuracy and display the electrode entry points (EPs) and ...