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  1. Article

    Open Access

    Genetic alterations and allele frequency of BRAF V600E and TERT mutation in papillary thyroid carcinoma with intermediate-to-high recurrence risk: a retrospective study

    The predictive value of allele frequency (AF) of BRAF V600E and TERT mutations in papillary thyroid carcinoma (PTC) remains controversial. We aimed to investigate the AF of BRAF V600E and TERT mutations in interm...

    Jiayu Huang, Jiazhi Wang, **gchao Xv, **gran Wang in Clinical and Experimental Medicine (2024)

  2. No Access

    Article

    Two-stage generative adversarial networks for metal artifact reduction and visualization in ablation therapy of liver tumors

    The strong metal artifacts produced by the electrode needle cause poor image quality, thus preventing physicians from observing the surgical situation during the puncture process. To address this issue, we pro...

    Duan Liang, Shunan Zhang, Ziqi Zhao in International Journal of Computer Assisted… (2023)

  3. Article

    Open Access

    Expression of TXLNA in brain gliomas and its clinical significance: a bioinformatics analysis

    To analyze the expression of TXLNA in brain gliomas and its clinical significance.

    Bowen Hu, Desheng Chen, Yang Li, Shan Yu, Liangwen Kuang in Chinese Neurosurgical Journal (2023)

  4. No Access

    Article

    Real-Time Navigation with Guide Template for Pedicle Screw Placement Using an Augmented Reality Head-Mounted Device: A Proof-of-Concept Study

    This study aims to explore the real-time navigation with guide template using an augmented reality head-mounted device (ARHMD) for pedicle screw placement.

    Haowei Li, Peihai Zhang, Guangzhi Wang, Huiting Liu in Indian Journal of Orthopaedics (2023)

  5. No Access

    Article

    Morphometric change in intervertebral foramen after percutaneous endoscopic lumbar foraminotomy: an in vivo radiographic study based on three-dimensional foramen reconstruction

    This study aimed to perform in vivo three-dimensional (3D) quantitative measurements of morphometric changes in the foramen in patients with lumbar foraminal stenosis (LFS) undergoing percutaneous endoscopic l...

    Tianyi Wang, Lei Wang, Lei Zang, Guangzhi Wang, Wuke Peng in International Orthopaedics (2023)

  6. Article

    Open Access

    A self-efficacy-enhancing physical activity intervention in women with high-risk factors for gestational diabetes mellitus: study protocol for a randomized clinical trial

    Gestational diabetes mellitus (GDM) is one of the most common medical disorders in pregnancy. Evidence has demonstrated that moderate-intensity physical activity may reduce the risk of gestational diabetes. Ho...

    **ao Yang, Ji Zhang, **angzhi Wang, Yi Xu, Li Sun, Yingli Song, Ruijuan Bai in Trials (2022)

  7. No Access

    Article

    B7 homolog 3 induces lung metastasis of breast cancer through Raf/MEK/ERK axis

    The essential action of B7 homolog 3 (B7-H3) in different diseases and cancers has been documented. We here focused on its role in breast cancer through the Raf/MEK/ERK axis regarding lung metastasis.

    Shuai Wang, **nyan Zhang, Houfa Ning, Senyi Dong in Breast Cancer Research and Treatment (2022)

  8. Article

    Open Access

    New biomarker: the gene HLA-DRA associated with low-grade glioma prognosis

    Low-grade gliomas (LGG) are WHO grade II tumors presenting as the most common primary malignant brain tumors in adults. Currently, LGG treatment involves either or a combination of surgery, radiation therapy, ...

    Desheng Chen, Jiawei Yao, Bowen Hu, Liangwen Kuang in Chinese Neurosurgical Journal (2022)

  9. Article

    Open Access

    Effectiveness of renal denervation in the treatment of hypertension: a literature review

    Catheter-based renal denervation has been studied as a potential therapeutic option to reduce high blood pressure (BP). Preclinical studies in some experimental models have demonstrated an antihypertensive eff...

    Riya Tejas Shah, Brian **angzhi Wang in Clinical Hypertension (2022)

  10. No Access

    Article

    A convenient and stable vertebrae instance segmentation method for transforaminal endoscopic surgery planning

    Transforaminal endoscopic surgery (TES) is effective for treatment of intervertebral disc-related diseases. To avoid injury to the critical structures, preoperative planning is required to find a safe working ...

    Wuke Peng, Liang Li, Libin Liang, Hui Ding in International Journal of Computer Assisted… (2021)

  11. Article

    Open Access

    Haemorrhagic retroperitoneal paraganglioma initially manifesting as acute abdomen: a rare case report and literature review

    Paragangliomas (PGLs) are extremely rare neuroendocrine tumours arising from extra-adrenal chromaffin cells. PGLs are clinically rare, difficult to diagnose and usually require surgical intervention. PGLs most...

    Yanliang Yang, Guangzhi Wang, Haofeng Lu, Yaqing Liu, Shili Ning, Fuwen Luo in BMC Surgery (2020)

  12. No Access

    Article

    Multiple objective planning for thermal ablation of liver tumors

    Preoperative treatment planning is key to ensure successful thermal ablation of liver tumors. The planning aims to minimize the number of electrodes required for complete ablation and the damage to the surroun...

    Libin Liang, Derek Cool, Nirmal Kakani in International Journal of Computer Assisted… (2020)

  13. Article

    Open Access

    Design of a robot-assisted system for transforaminal percutaneous endoscopic lumbar surgeries: study protocol

    Transforaminal percutaneous endoscopic lumbar surgeries (PELS) for lumbar disc herniation and spinal stenosis are growing in popularity. However, there are some problems in the establishment of the working cha...

    Ning Fan, Shuo Yuan, Peng Du, Wenyi Zhu in Journal of Orthopaedic Surgery and Research (2020)

  14. Article

    Open Access

    The combination of Radix Astragali and Radix Angelicae Sinensis attenuates the IFN-γ-induced immune destruction of hematopoiesis in bone marrow cells

    Radix Astragali and Radix Angelicae Sinensis are two herbs that compose Danggui Buxue Tang (an herbal formula for treatment of anemia diseases). In this study, we explored the molecular mechanism and effective ta...

    Juan Liu, Jie Wei, Changzhi Wang in BMC Complementary and Alternative Medicine (2019)

  15. No Access

    Article

    A “eye-in-body” integrated surgery robot system for stereotactic surgery

    Current stereotactic surgical robots system relies on cumbersome operations such as calibration, tracking and registration to establish the accurate intraoperative coordinate transformation chain, which makes ...

    Liang Li, Julia Wu, Hui Ding, Guangzhi Wang in International Journal of Computer Assisted… (2019)

  16. Article

    Prostaglandin E2/EP2 receptor signalling pathway promotes diabetic retinopathy in a rat model of diabetes

    Diabetic retinopathy is a common microvascular complication of diabetes mellitus and is initiated by inflammation and apoptosis-associated retinal endothelial cell damage. Prostaglandin E2 (PGE2) has emerged as a...

    Man Wang, Yangningzhi Wang, Tianhua **e, Pengfei Zhan, Jian Zou in Diabetologia (2019)

  17. No Access

    Article

    Robust extraction for low-contrast liver tumors using modified adaptive likelihood estimation

    Liver tumor extraction is essential for liver ablation surgery planning and treatment. For accurate and robust tumor segmentation, we propose a semiautomatic method using adaptive likelihood classification wit...

    Qing Huang, Hui Ding, **aodong Wang in International Journal of Computer Assisted… (2018)

  18. No Access

    Article

    An X-ray-free method to accurately identify the elbow flexion–extension axis for the placement of a hinged external fixator

    Identifying the elbow flexion–extension (F–E) movement axis is important for placing a hinged elbow external fixator. An X-ray fluoroscopy-based method is widely used in clinical practice, exposing the patient...

    Jian Song, Hui Ding, Wei Han, Junqiang Wang in International Journal of Computer Assisted… (2018)

  19. No Access

    Article

    An automatic markerless registration method for neurosurgical robotics based on an optical camera

    Current markerless registration methods for neurosurgical robotics use the facial surface to match the robot space with the image space, and acquisition of the facial surface usually requires manual interactio...

    Fanle Meng, Fangwen Zhai, Bowei Zeng in International Journal of Computer Assisted… (2018)

  20. No Access

    Article

    A surgical robot with augmented reality visualization for stereoelectroencephalography electrode implantation

    Using existing stereoelectroencephalography (SEEG) electrode implantation surgical robot systems, it is difficult to intuitively validate registration accuracy and display the electrode entry points (EPs) and ...

    Bowei Zeng, Fanle Meng, Hui Ding in International Journal of Computer Assisted… (2017)

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