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    Article

    Acid–Base Bifunctional Fiber as Highly Active Catalyst for the Tandem Deprotection-Knoevenagel Reaction

    A serious of phenol and amine bifunctionalized polyacrylonitrile fibers have been prepared and used to catalyze the tandem deprotection-Knoevenagel reaction. Among them, the phenol and tertiary amine bifunctio...

    Ziyi Chen, Bo Ren, Lu Wang, Jiangyu Zheng, Boyu Shao, Liying Wu in Catalysis Letters (2024)

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    Open Access

    Semi-rational engineering an aldo–keto reductase for stereocomplementary reduction of α-keto amide compounds

    Enantio-pure α-hydroxy amides are valuable intermediates for the synthesis of chiral pharmaceuticals. The asymmetric reduction of α-keto amides to generate chiral α-hydroxy amides is a difficult and challengin...

    Ruixuan Bai, Baoling Chen, Liangyu Zheng in Microbial Cell Factories (2023)

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    Article

    Porous sponge with surface modified for superhydrophobic/superoleophilic and special functionalization

    Sponge-based materials have attracted wide attention because of their low cost, easy to manufacture and environmental-friendly. Sponge-based materials have the characteristics of large porosity and large speci...

    **angyu Zheng, Haiwei Zhang, Mengyue Liu, **ng Zhou in Journal of Polymer Research (2022)

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    Article

    Investigations of Chirality Effects on Undifferentiated State of Mesenchymal Stem Cells Using Soft Nanofibrous Oligopeptide Hydrogels

    Soft nanofibrous oligopeptide hydrogels consisting of self-assembled l- and d-form Fmoc-Phe-Phe-Cys networks photo-cross-linked by poly(ethylene glycol)-dimethacrylate, which are referred to as l- and d-gel, resp...

    Toru Yoshitomi, Hangyu Zheng, Keitaro Yoshimoto in Analytical Sciences (2021)

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    Article

    Rational enhancement of enzyme-catalyzed enantioselective reaction by construction of recombinant enzymes based on additive strategy

    A rational enhancement of kinetic resolution process for producing (S)-N-(2-ethyl-6-methylphenyl) alanine from racemic methyl ester using lipase B from Candida antarctica (CalB) was investigated. With the benefit...

    Yu Han, **aoxue Zhou, Liangyu Zheng in Bioprocess and Biosystems Engineering (2019)

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    Article

    Study on the enantioselectivity inhibition mechanism of acetyl-coenzyme A carboxylase toward haloxyfop by homology modeling and MM-PBSA analysis

    Acetyl-coenzyme A carboxylase (ACCase) has been identified as one of the most important targets of herbicide Aryloxyphenoxypropionates (APPs). ACCase shows different enantioselectivity toward APPs, and only (R)-e...

    ** Tao, Guirong Zhang, Aijun Zhang, Liangyu Zheng in Journal of Molecular Modeling (2012)

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    Article

    l-Valine Dipeptide Organocatalysts with Two Amide Units for the Direct Asymmetric Aldol Reaction in Brine

    A series of valine dipeptide organocatalysts containing a primary amine group and two amide units have been developed and evaluated in the direct asymmetric intermolecular aldol reaction of 4-nitrobenzaldehyde...

    Wenbo Huang, Hua Tian, Hao Xu, Liangyu Zheng, Qingwen Liu in Catalysis Letters (2011)