17 Result(s)

Article

Comprehensive analysis of T-cell regulatory factors and tumor immune microenvironment in stomach adenocarcinoma

Gastric cancer (GC) is one of the most prevalent malignant tumors worldwide and is associated with high morbidity and mortality rates. However, the specific biomarkers used to predict the postoperative prognos...

Shuchang Wang, Weifeng Zhang, **nrui Wu, Zhu Zhu, Yuanbiao Chen, Wangrui Liu… in BMC Cancer (2024)

Article

Nanomaterial-encapsulated STING agonists for immune modulation in cancer therapy

The cGAS-STING signaling pathway has emerged as a critical mediator of innate immune responses, playing a crucial role in improving antitumor immunity through immune effector responses. Targeting the cGAS-STIN...

** Chen, Zhijie Xu, Tongfei Li, Abhimanyu Thakur, Yu Wen, Kui Zhang… in Biomarker Research (2024)

Article

Single-cell RNA-seq analysis decodes the kidney microenvironment induced by polystyrene microplastics in mice receiving a high-fat diet

In recent years, the environmental health issue of microplastics has aroused an increasingly significant concern. Some studies suggested that exposure to polystyrene microplastics (PS-MPs) may lead to renal in...

Wenhao Xu, Shiqi Ye, Wangrui Liu, Huaqi Guo, Linhui Zhang… in Journal of Nanobiotechnology (2024)

Article

Integrating genomic and multiomic data for Angelica sinensis provides insights into the evolution and biosynthesis of pharmaceutically bioactive compounds

Angelica sinensis roots (Angelica roots) are rich in many bioactive compounds, including phthalides, coumarins, lignans, and terpenoids. However, the molecular bases for their biosynthesis are still poorly unders...

Shiming Li, Tsan-Yu Chiu, **n **, Dong Cao, Meng Xu, Mingzhi Zhu… in Communications Biology (2023)

Article

FMSA: a meta-learning framework-based fast model stealing attack technique against intelligent network intrusion detection systems

Intrusion detection systems are increasingly using machine learning. While machine learning has shown excellent performance in identifying malicious traffic, it may increase the risk of privacy leakage. This p...

Kaisheng Fan, Weizhe Zhang, Guangrui Liu, Hui He in Cybersecurity (2023)

Article

Surface-anchored microbial enzyme-responsive solid lipid nanoparticles enabling colonic budesonide release for ulcerative colitis treatment

Colon-targeted oral drug delivery systems (CDDSs) are desirable for the treatment of ulcerative colitis (UC), which is a disease with high relapse and remission rates associated with immune system inflammation...

Yipeng Zhang, Liying Wang, Zi-Dan Wang, Quan Zhou… in Journal of Nanobiotechnology (2023)

Article

Publisher Correction: Long non-coding RNA SNHG6 couples cholesterol sensing with mTORC1 activation in hepatocellular carcinoma

Fangzhou Liu, Tian Tian, Zhen Zhang, Shanshan **e, Jiecheng Yang… in Nature Metabolism (2022)

Article

Deciphering the role of miR-187-3p/LRFN1 axis in modulating progression, aerobic glycolysis and immune microenvironment of clear cell renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) is one of the most common malignant genitourinary cancers with high recurrence risk worldwide. Recently, multi-omics data facilitate obtaining a molecular landscape of t...

Wenhao Xu, Wangrui Liu, Aihetaimujiang Anwaier, ** Tian, Jiaqi Su… in Discover Oncology (2022)

Article

A bioinformatic analysis study of m⁷G regulator-mediated methylation modification patterns and tumor microenvironment infiltration in glioblastoma

Glioblastoma is one of the most common brain cancers in adults, and is characterized by recurrence and little curative effect. An effective treatment for glioblastoma patients remains elusive worldwide. 7-meth...

**nrui Wu, Chuanyu Li, Zhisu Wang, Yundi Zhang, Shifan Liu, Siqi Chen… in BMC Cancer (2022)

Article

A comparative study of two robotic thyroidectomy procedures: transoral vestibular versus bilateral axillary-breast approach

To compare the surgical outcomes between the transoral-vestibular robotic thyroidectomy (TOVRT) and bilateral axillo-breast approach robotic thyroidectomy (BABART).

Qingqing He, Jian Zhu, **aolei Li, Meng Wang, Gang Wang, Peng Zhou, Dan Wang… in BMC Surgery (2022)

Article

Length-based separation of Bacillus subtilis bacterial populations by viscoelastic microfluidics

In this study, we demonstrated the label-free continuous separation and enrichment of Bacillus subtilis populations based on length using viscoelastic microfluidics. B. subtilis, a gram-positive, rod-shaped bacte...

** Liu, Hangrui Liu, Lucie Semenec, Dan Yuan, Sheng Yan… in Microsystems & Nanoengineering (2022)

Article

Prodrug polymeric micelles integrating cancer-associated fibroblasts deactivation and synergistic chemotherapy for gastric cancer

The prognosis of patients with advanced gastric cancer (GC) remains unsatisfactory owing to distant metastasis and resistance to concurrent systemic therapy. Cancer-associated fibroblasts (CAFs), as essential ...

Sheng Zheng, Jiafeng Wang, Ning Ding, Wenwen Chen… in Journal of Nanobiotechnology (2021)

Article

Clinical analysis of metastatic characteristics of infrapyloric lymph nodes (No.206) and terminal ileum lymph nodes in patients with right colon cancer

D3 or complete mesocolic excision (CME) surgery has become a common surgical procedure for the treatment of colon cancer metastasis. Clinical misuse and overuse of lymph node dissection bring unnecessary burde...

Jiangrui Liu, Yibin Su, **ng Liu, **fu Zhuang… in World Journal of Surgical Oncology (2021)

Article

Fruquintinib inhibits VEGF/VEGFR2 axis of choroidal endothelial cells and M1-type macrophages to protect against mouse laser-induced choroidal neovascularization

Wet age-related macular degeneration, which is characterized by choroidal neovascularization (CNV) and induces obvious vision loss. Vascular endothelial growth factor (VEGF) family member VEGF-A (also named as...

**aojuan Liu, Aisong Guo, Yuanyuan Tu, Wendie Li, Lele Li… in Cell Death & Disease (2020)

Article

Robotic lateral cervical lymph node dissection via bilateral axillo-breast approach for papillary thyroid carcinoma: a single-center experience of 260 cases

To evaluate the feasibility and safety of robotic lateral cervical lymph node dissection via BABA, 260 thyroid cancer patients with suspected level II, III, IV, and V_b lymph node metastasis were selected. The lat...

Qingqing He, Jian Zhu, Dayong Zhuang, Ziyi Fan, Luming Zheng… in Journal of Robotic Surgery (2020)

Article

GDC-0449 improves the antitumor activity of nano-doxorubicin in pancreatic cancer in a fibroblast-enriched microenvironment

Pancreatic cancer is one of the most lethal human cancers that currently does not have effective therapies. Novel treatments including nanomedicines and combination therapies are thus urgently needed for these...

Quan Zhou, Yongcun Zhou, **angrui Liu, Youqing Shen in Scientific Reports (2017)

Article

Novel insights into mitochondrial gene rearrangement in thrips (Insecta: Thysanoptera) from the grass thrips, Anaphothrips obscurus

We sequenced the mitochondrial (mt) genome of the grass thrips, Anaphothrips obscurus, which is highly rearranged and differs from the four thrips species reported previously in the arrangement of both tRNA genes...

Hangrui Liu, Hu Li, Fan Song, Wenyi Gu, **ian Feng, Wanzhi Cai… in Scientific Reports (2017)