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Emergence of an ST1934:KL121 hypervirulent Klebsiella pneumoniae carrying a novel virulence-resistance hybrid plasmid with chromosomal integration of ICEKp1

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  1. Article

    Open Access

    Identification of isothiazolones analogues as potent bactericidal agents against antibiotic resistant CRE and MRSA strains

    Carbapenem-resistant Enterobacterales (CRE) has emerged as a worldwide spread nosocomial superbug exhibiting antimicrobial resistance (AMR) to all current antibiotics, leaving limited options for treating its ...

    Wenbin **, Chen Xu, Ning Dong, Kaichao Chen, Die Zhang, **hua Ning in BMC Chemistry (2023)

  2. Article

    Open Access

    Diagnostic value of combining preoperative inflammatory markers ratios with CA199 for patients with early-stage pancreatic cancer

    An early diagnosis of pancreatic cancer (PC) is extremely difficult because of the lack of sensitive liquid biopsy methods and effective biomarkers. We attempted to evaluate whether circulating inflammatory ma...

    Yuanlong Gu, Qian** Hua, Zhipeng Li, **ngli Zhang, Changjie Lou in BMC Cancer (2023)

  3. Article

    Open Access

    Gene regulatory network and abundant genetic variation play critical roles in heading stage of polyploidy wheat

    The extensive adaptability of polyploidy wheat is attributed to its complex genome, and accurately controlling heading stage is a prime target in wheat breeding process. Wheat heading stage is an essential gro...

    Chaonan Shi, Lei Zhao, **angfen Zhang, Guoguo Lv, Yubo Pan, Feng Chen in BMC Plant Biology (2019)

  4. Article

    Open Access

    Nuclear MTA1 overexpression is associated with aggressive prostate cancer, recurrence and metastasis in African Americans

    Metastasis-associated protein 1 (MTA1), a negative epigenetic modifier, plays a critical role in prostate cancer (PCa) progression. We hypothesized that MTA1 overexpression in primary tumor tissues can predict...

    Steven J. Dias, **nchun Zhou, Marina Ivanovic, Michael P. Gailey in Scientific Reports (2013)