5 Result(s)
within
**angbo Chen
Life Sciences
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Article
Open AccessWFDC3 inhibits tumor metastasis by promoting the ERβ-mediated transcriptional repression of TGFBR1 in colorectal cancer
Estrogen plays a protective role in colorectal cancer (CRC) and primarily functions through estrogen receptor β (ERβ). However, clinical strategies for CRC therapy associated with ERβ are still under investiga...
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Article
Open AccessA stop-gain mutation in GXYLT1 promotes metastasis of colorectal cancer via the MAPK pathway
Genomic instability plays a key role in the initiation and progression of colorectal cancer (CRC). Although cancer driver genes in CRC have been well characterized, identifying novel genes associated with carc...
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Article
β-Aminoisobutyric acid supplementation attenuated salt-sensitive hypertension in Dahl salt-sensitive rats through prevention of insufficient fumarase
The human Dietary Approaches to Stop Hypertension-Sodium Trial has shown that β-aminoisobutyric acid (BAIBA) may prevent the development of salt-sensitive hypertension (SSHT). However, the specific antihyperte...
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Article
Trehalose attenuates TGF-β1-induced fibrosis of hSCFs by activating autophagy
Conjunctival fibrosis is a process of extracellular matrix accumulation and the appearance of myofibroblasts in subconjunctival fibroblasts induced by injury or inflammation, which can significantly reduce the...
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Article
Diverse bacterial symbionts of insect-pathogentic fungi and possible impact on the maintenance of virulence during infection
Bacterial-fungal interactions (BFIs) which have important ramifications for the biology of the interacting partners have been demonstrated extensively. Here we show for the first time that diverse bacterial sy...
