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Article
Open AccessNovel radiopaque ethanol injection: physicochemical properties, animal experiments, and clinical application in vascular malformations
Despite the efficacy of absolute ethanol (EtOH), its radiolucency introduces several risks in interventional therapy for treating vascular malformations. This study aims to develop a novel radiopaque ethanol i...
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Article
Open AccessSmooth muscle NF90 deficiency ameliorates diabetic atherosclerotic calcification in male mice via FBXW7-AGER1-AGEs axis
Hyperglycemia accelerates calcification of atherosclerotic plaques in diabetic patients, and the accumulation of advanced glycation end products (AGEs) is closely related to the atherosclerotic calcification. Her...
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Article
A homopolymolybdate-supported plate-like 2D cobalt network constructed from a new pyrazole-amide-pyridyl ligand: highly electrochemical activity in both capacitive performance and the detection of Cr (VI)
By employing a new semi-rigid pyrazole-amide-derived bis(pyridyl) ligand [N,N'-bis(4-picolylamine)-1-hydropyrazole (4-dpap)], a new homopolymolybdate-based two-dimensional (2D) plate-like complex [Co(4-dpap)(H2O)...
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Article
Strength and fracture properties of coral concrete under impact of coral aggregate type and fiber hybridization
Seawater coral aggregate concrete (SCAC) has demonstrated advantages in reducing material cost and energy consumption of marine infrastructure on reefs and islands. However, SCAC exhibits increased brittleness...
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Article
Cardiac-specific deletion of BRG1 ameliorates ventricular arrhythmia in mice with myocardial infarction
Malignant ventricular arrhythmia (VA) after myocardial infarction (MI) is mainly caused by myocardial electrophysiological remodeling. Brahma-related gene 1 (BRG1) is an ATPase catalytic subunit that belongs t...
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Article
Nondestructive technique for identifying nuclides using neutron resonance transmission analysis at CSNS Back-n
Nondestructive and noninvasive neutron assays are essential applications of neutron techniques. Neutron resonance transmission analysis (NRTA) is a powerful nondestructive method for investigating the elementa...
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Article
Molecular dynamics study of hydrogen-induced cracking behavior of ferrite–pearlite gas transmission pipeline steel
Hydrogen embrittlement of pipelines depends on the hydrogen-induced cracking behavior of the pipeline steel microstructure. Based on molecular dynamics analysis, the ferrite–cementite (α-Fe/Fe3C) lamellar atomic ...
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Chapter and Conference Paper
Application of Pre-stack Poisson Impedance Inversion in the Prediction of Igneous Rocks
The carbonate reservoir is complicated by igneous rocks in Block M of Santos Basin. Igneous rocks have weak - strong amplitude, low-high frequency, and chaotic-continuous seismic reflection features, which is ...
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Article
Open AccessOral pathogens exacerbate Parkinson’s disease by promoting Th1 cell infiltration in mice
Parkinson’s disease (PD) is a common chronic neurological disorder with a high risk of disability and no cure. Periodontitis is an infectious bacterial disease occurring in periodontal supporting tissues. Stud...
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Article
Open AccessSRSF2 is required for mRNA splicing during spermatogenesis
RNA splicing plays significant roles in fundamental biological activities. However, our knowledge about the roles of alternative splicing and underlying mechanisms during spermatogenesis is limited.
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Article
Cobalt-based Metalloporphyrins As Efficient Electro-catalysts for Hydrogen Evolution From Acetic Acid and Water
Four molecular electrocatalysts based on cobalt complexes, CoT(X)PP (X = H (1), OH (2), CN (3), COOH (4)), were prepared from meso-tetra-p-X-phenylporphin (H2T(X)PP, X = H, OH, CN, COOH) by reaction with cobalt a...
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Article
A novel AGK splicing mutation in a patient with Sengers syndrome and left ventricular non-compaction cardiomyopathy
Sengers syndrome characterized by hypertrophic cardiomyopathy is an extremely rare genetic disorder. Sengers syndrome associated with left ventricular non-compaction (LVNC) has not been described.
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Article
ASH2L regulates postnatal neurogenesis through Onecut2-mediated inhibition of TGF-β signaling pathway
The ability of neural stem/progenitor cells (NSPCs) to proliferate and differentiate is required through different stages of neurogenesis. Disturbance in the regulation of neurogenesis causes many neurological...
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Article
Open AccessNdufa4 Regulates the Proliferation and Apoptosis of Neurons via miR-145a-5p/Homer1/Ccnd2
The Dandy–Walker malformation (DWM) is characterized by neuron dysregulation in embryonic development; however, the regulatory mechanisms associated with it are unclear. This study aimed to investigate the rol...
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Article
Open AccessIntegrative multi-omics analysis depicts the methylome and hydroxymethylome in recurrent bladder cancers and identifies biomarkers for predicting PD-L1 expression
Urinary bladder cancer (UBC) is a common malignancy of the urinary tract; however, the mechanism underlying its high recurrence and responses to immunotherapy remains unclear, making clinical outcome predictio...
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Article
Analysis of Chinese Medical Syndrome Features of Ischemic Stroke Based on Similarity of Symptoms Subgroup
To derive the Chinese medicine (CM) syndrome classification and subgroup syndrome characteristics of ischemic stroke patients.
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Article
Open AccessLZTFL1 inhibits kidney tumor cell growth by destabilizing AKT through ZNRF1-mediated ubiquitin proteosome pathway
LZTFL1 is a tumor suppressor located in chromosomal region 3p21.3 that is deleted frequently and early in various cancer types including the kidney cancer. However, its role in kidney tumorigenesis remains unk...
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Article
Prediction of blast furnace gas generation based on data quality improvement strategy
The real-time energy flow data obtained in industrial production processes are usually of low quality. It is difficult to accurately predict the short-term energy flow profile by using these field data, which ...
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Article
Open AccessImproving bowel preparation for colonoscopy with a smartphone application driven by artificial intelligence
Optimal bowel preparation is a prerequisite for a successful colonoscopy; however, the rate of inadequate bowel preparation remains relatively high. In this study, we establish a smartphone app that assesses p...
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Article
Open AccessThe MING proposal at SHINE: megahertz cavity enhanced X-ray generation
The cavity-based X-ray free-electron laser (XFEL) has promise in producing fully coherent pulses with a bandwidth of a few meV and very stable intensity, whereas the currently existing self-amplified spontaneo...
