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Author Correction: The power of genetic diversity in genome-wide association studies of lipids
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Map** genomic loci implicates genes and synaptic biology in schizophrenia
Schizophrenia has a heritability of 60–80%1, much of which is attributable to common risk alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with schizophrenia and 243,649 con...
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The power of genetic diversity in genome-wide association studies of lipids
Increased blood lipid levels are heritable risk factors of cardiovascular disease with varied prevalence worldwide owing to different dietary patterns and medication use1. Despite advances in prevention and treat...
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Open AccessConfirming the TMEM232 gene associated with atopic dermatitis through targeted capture sequencing
Atopic dermatitis (AD) is a common and complex skin disorder, and the 5q22.1 region had been reported to be associated with AD. To confirm the susceptibility gene for AD in the 5q22.1 region by haplotype and t...
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Open AccessArbuscular mycorrhizal trees influence the latitudinal beta-diversity gradient of tree communities in forests worldwide
Arbuscular mycorrhizal (AM) and ectomycorrhizal (EcM) associations are critical for host-tree performance. However, how mycorrhizal associations correlate with the latitudinal tree beta-diversity remains untes...
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Open AccessRALYL increases hepatocellular carcinoma stemness by sustaining the mRNA stability of TGF-β2
Growing evidences suggest that cancer stem cells exhibit many molecular characteristics and phenotypes similar to their ancestral progenitor cells. In the present study, human embryonic stem cells are induced ...
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Open AccessAuthor Correction: The Apostasia genome and the evolution of orchids
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Open AccessDietary magnesium deficiency impaired intestinal structural integrity in grass carp (Ctenopharyngodon idella)
Grass carp (223.85–757.33 g) were fed diets supplemented with magnesium (73.54–1054.53 mg/kg) for 60 days to explore the impacts of magnesium deficiency on the growth and intestinal structural integrity of the...
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Article
Open AccessAutomatic multiple zebrafish tracking based on improved HOG features
As an excellent model organism, zebrafish have been widely applied in many fields. The accurate identification and tracking of individuals are crucial for zebrafish shoaling behaviour analysis. However, multi-...
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Open AccessIL-13 may be involved in the development of CAD via different mechanisms under different conditions in a Chinese Han population
Interleukin-13 (IL-13) has important functions in atherosclerosis, but its role in coronary artery disease (CAD) is unclear. Here, we studied the genetic role of IL-13 in CAD in a Chinese Han population using ...
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Open AccesspGlyco 2.0 enables precision N-glycoproteomics with comprehensive quality control and one-step mass spectrometry for intact glycopeptide identification
The precise and large-scale identification of intact glycopeptides is a critical step in glycoproteomics. Owing to the complexity of glycosylation, the current overall throughput, data quality and accessibilit...
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Open AccessThe Apostasia genome and the evolution of orchids
WebComparing the whole genome sequence of Apostasia shenzhenica with transcriptome and genome data from five orchid subfamilies permits the reconstruction of an ancestral gene toolkit, providing insight into orch...
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Open AccessUSP13 negatively regulates antiviral responses by deubiquitinating STING
STING (also known as MITA) is critical for host defence against viruses and the activity of STING is regulated by ubiquitination. However, the deubiquitination of STING is not fully understood. Here, we show t...
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Open AccessBiological characteristics comparison of HBV rtA181T mutants with truncated or substituted HBsAg expression in vitro and in vivo model systems
The hepatitis B virus(HBV) polymerase rtA181T mutation is selected during long-term antiviral therapy. As the polymerase gene completely overlaps with the envelope (S) gene, HBV rtA181T mutation also carries s...
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Open AccessErratum: Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma
Nature Communications 7: Article number: 12992 (2016); Published: 5 October 2016; Updated: 8 November 2016 The original version of this Article contained an error in the spelling of the author Tin-Lap Lee, whi...
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Open AccessGenomic and oncogenic preference of HBV integration in hepatocellular carcinoma
Hepatitis B virus (HBV) can integrate into the human genome, contributing to genomic instability and hepatocarcinogenesis. Here by conducting high-throughput viral integration detection and RNA sequencing, we ...
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Open AccessDiversity of bacterial dimethylsulfoniopropionate degradation genes in surface seawater of Arctic Kongsfjorden
Dimethylsulfoniopropionate (DMSP), which is the major source of organic sulfur in the world’s oceans, plays a significant role in the global sulfur cycle. This compound is rapidly degraded by marine bacteria e...
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Open AccessA genetic analysis of 23 Chinese patients with hemophilia B
Hemophilia B (HB) is an X-linked recessive bleeding disorder caused by mutations in the coagulation factor IX (FIX) gene. Genoty** patients with HB is essential for genetic counseling and provides useful inf...
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Open AccessIdentification of new susceptibility loci for IgA nephropathy in Han Chinese
IgA nephropathy (IgAN) is one of the most common primary glomerulonephritis. Previously identified genome-wide association study (GWAS) loci explain only a fraction of disease risk. To identify novel susceptib...
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Open AccessExpression variations of connective tissue growth factor in pulmonary arteries from smokers with and without chronic obstructive pulmonary disease
Cigarette smoking contributes to the development of pulmonary hypertension (PH) complicated with chronic obstructive pulmonary disease (COPD) and the pulmonary vascular remodeling, the structural basis of PH, ...