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Article
A non-invasive glucose sensor based on 3D reduced graphene oxide-MXene and AuNPs composite electrode for the detection of saliva glucose
Regular monitoring of blood glucose levels is crucial in diabetes management. Commonly used procedures may be invasive and can lead to cross-infection and inflammation. Therefore, a safe, non-invasive blood gl...
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Article
Operando measurement of lattice deformation profiles of synchrotron radiation monochromator
This study presents a new method for characterizing the thermal lattice deformation of a monochromator with high precision under service conditions and first reports the operando measurements of nanoscale ther...
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Article
Dynamic change of metabolic dysfunction-associated steatotic liver disease in patients with hepatitis C virus infection after achieving sustained virologic response with direct-acting antivirals
Information on the dynamics of metabolic dysfunction-associated steatotic liver disease (MASLD) among hepatitis C virus patients achieving sustained virologic response (SVR12) with direct-acting antivirals (DAAs)...
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Article
Open AccessA Phase 3, Randomized, Controlled Trial Evaluating the Efficacy and Safety of Ropeginterferon Alfa-2b in Patients with Moderate COVID-19
Ropeginterferon alfa-2b is a novel mono-pegylated proline-interferon. This clinical study aimed to evaluate its antiviral efficacy of ropeginterferon alfa-2b against SARS-CoV-2 infection.
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Article
Clinical implications of CSF-ctDNA positivity in newly diagnosed diffuse large B cell lymphoma
The clinical implications of CSF-ctDNA positivity in newly diagnosed diffuse large B cell lymphoma (ND-DLBCL) remains largely unexplored. One hundred ND-DLBCL patients were consecutively enrolled as training c...
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Article
Simplified p-i-n Perovskite Solar Cells with a Multifunctional Polyfullerene Electron Transporter
In prevailing p-i-n perovskite solar cells (PSCs), solution-processible fullerene molecules are widely used as electron-transporting layers (ETLs) but they typically suffer from poor uniformity and undesirable...
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Article
Open AccessEfficientNet-based machine learning architecture for sleep apnea identification in clinical single-lead ECG signal data sets
Our objective was to create a machine learning architecture capable of identifying obstructive sleep apnea (OSA) patterns in single-lead electrocardiography (ECG) signals, exhibiting exceptional performance wh...
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Article
Correction: Characteristics and evaluation of C1 posterior arch variation for transpedicular screw placement between patients with and without basilar invagination
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Article
PHPB ameliorates memory deficits and reduces oxidative injury in Alzheimer’s disease mouse model by activating Nrf2 signaling pathway
Alzheimer’s disease (AD), a progressive neurodegenerative disorder, is the most common cause of dementia in elderly people and substantially affects patient quality of life. Oxidative stress is considered a ke...
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Article
Open AccessCorrelation between higher lateral tibial slope and inferior long term subjective outcomes following single bundle anterior cruciate ligament reconstruction
The impact of anatomical factors, such as the lateral tibial slope (LTS), on outcomes following anterior cruciate ligament (ACL) reconstruction is an area of growing interest. This study was led by the observa...
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Article
Open AccessAluminum-doped zinc oxide thickness controllable wavelengths in visible light and high responsivity devices using interrupted flow atomic layer deposition
In this study, we develop a highly sensitive visible light photodetector that utilizes a thin-film structure composed of low-cost aluminum-doped zinc oxide (AZO) and n-type silicon. The AZO thickness can be ad...
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Article
High-precision X-ray polarimeter based on channel-cut crystals
We report on using synthetic silicon for a high-precision X-ray polarimeter comprising a polarizer and an analyzer, each based on a monolithic channel-cut crystal used at multiple Brewster reflections with a B...
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Article
Open AccessArsenic trioxide augments immunogenic cell death and induces cGAS-STING-IFN pathway activation in hepatocellular carcinoma
The treatment of hepatocellular carcinoma (HCC) is particularly challenging due to the inherent tumoral heterogeneity and easy resistance towards chemotherapy and immunotherapy. Arsenic trioxide (ATO) has emer...
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Article
Performance of ChatGPT on the Taiwan urology board examination: insights into current strengths and shortcomings
To compare ChatGPT-4 and ChatGPT-3.5's performance on Taiwan urology board examination (TUBE), focusing on answer accuracy, explanation consistency, and uncertainty management tactics to minimize score penalti...
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Article
Open AccessUtility of polygenic scores across diverse diseases in a hospital cohort for predictive modeling
Polygenic scores estimate genetic susceptibility to diseases. We systematically calculated polygenic scores across 457 phenotypes using genoty** array data from China Medical University Hospital. Logistic re...
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Article
Open AccessDeep learning assists in acute leukemia detection and cell classification via flow cytometry using the acute leukemia orientation tube
This study aimed to evaluate the sensitivity of AI in screening acute leukemia and its capability to classify either physiological or pathological cells. Utilizing an acute leukemia orientation tube (ALOT), on...
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Article
Open AccessRenal interstitial fibrotic assessment using non-Gaussian diffusion kurtosis imaging in a rat model of hyperuricemia
To investigate the feasibility of Diffusion Kurtosis Imaging (DKI) in assessing renal interstitial fibrosis induced by hyperuricemia.
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Article
Open AccessEffectiveness of binaural beat music combined with rhythmical photic stimulation on older people with depressive symptoms in long-term care institution: a quasi-experimental pilot study
Many older adults residing in long-term care often face issues like poor sleep, reduced vitality, and depression. Non-pharmacological approaches, specifically Binaural Beat Music (BBM) and Rhythmic Photic Stim...
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Article
Open AccessPrescribing cascades of antigout medications from thiazide diuretics in gout-naïve hypertensive adults receiving first-line pharmacological management
Prescribing cascade is a significant clinical problem but is often overlooked. We explore the incidence of the prescribing cascades of antigout medications related to thiazide treatment in gout-naïve hypertens...
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Article
Open AccessAuthor Correction: Antibodies from dengue patients with prior exposure to Japanese encephalitis virus are broadly neutralizing against Zika virus
