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  1. No Access

    Article

    Structural basis of the α1–β subunit interaction of voltage-gated Ca2+ channels

    High-voltage-activated Ca2+ channels are essential for diverse biological processes. They are composed of four or five subunits, including α1, α2-δ, β and γ (ref. 1). Their expression and function are critically ...

    Yu-hang Chen, Ming-hui Li, Yun Zhang, Lin-ling He, Yoichi Yamada in Nature (2004)

  2. No Access

    Article

    A conserved inverted repeat from rice plastome functions as an intrinsic transcription terminator

    Results from a previous rice transcription map** and the GeSTer algorithm analysis used in this in-vestigation for rice plastid genome suggest that an inverted repeat, IRsl8, in 3′ region of the plastid rps18 g...

    Lin Chi-Hui, Liang Yu-**, Chen Liang-Jwu in Chinese Science Bulletin (2005)

  3. No Access

    Article

    Early Cambrian ocean anoxia in South China

    Arising from: M. Wille, T. F. Nägler, B. Lehmann, S. Schröder & J. D. Kramers Nature 453, 767–769 (2008)10.1038/nature07072; Wille et al.

    Shao-Yong Jiang, Dao-Hui Pi, Christoph Heubeck, Hartwig Frimmel, Yu-** Liu in Nature (2009)

  4. No Access

    Article

    Molecular mechanism of the assembly of an acid-sensing receptor ion channel complex

    Polycystic kidney disease (PKD) family proteins associate with transient receptor potential (TRP) channel family proteins to form functionally important complexes. PKD proteins differ from known ion channel-fo...

    Yong Yu, Maximilian H. Ulbrich, Ming-hui Li, Scott Dobbins in Nature Communications (2012)

  5. Article

    Open Access

    A Photometric High-Throughput Method for Identification of Electrochemically Active Bacteria Using a WO3 Nanocluster Probe

    Electrochemically active bacteria (EAB) are ubiquitous in environment and have important application in the fields of biogeochemistry, environment, microbiology and bioenergy. However, rapid and sensitive meth...

    Shi-Jie Yuan, Hui He, Guo-** Sheng, Jie-Jie Chen, Zhong-Hua Tong in Scientific Reports (2013)

  6. Article

    Open Access

    Performance of breast cancer screening methods and modality among Chinese women: a report from a society-based breast screening program (SBSP) in Shanghai

    To evaluate the screening performance of individual and combined use of clinical breast examination, ultrasonography and mammography in Chinese women, we conducted a biennial breast cancer screening program am...

    Miao Mo, Guang-yu Liu, Ying Zheng, Lian-fang Di, Ya-jie Ji, Li-lang Lv in SpringerPlus (2013)

  7. Article

    Open Access

    Light trap** and surface plasmon enhanced high-performance NIR photodetector

    Heterojunctions near infrared (NIR) photodetectors have attracted increasing research interests for their wide-ranging applications in many areas such as military surveillance, target detection and light visio...

    Lin-Bao Luo, Long-Hui Zeng, Chao **e, Yong-Qiang Yu, Feng-**a Liang in Scientific Reports (2014)

  8. Article

    Open Access

    The complex jujube genome provides insights into fruit tree biology

    The jujube (Ziziphus jujuba Mill.), a member of family Rhamnaceae, is a major dry fruit and a traditional herbal medicine for more than one billion people. Here we present a high-quality sequence for the complex ...

    Meng-Jun Liu, ** Zhao, Qing-Le Cai, Guo-Cheng Liu, Jiu-Rui Wang in Nature Communications (2014)

  9. Article

    Open Access

    Concurrent radiotherapy and weekly chemotherapy of 5-fluorouracil and platinum agents for postoperative locoregional recurrence of oesophageal squamous cell carcinoma

    The most optimal management for postoperative locoregional recurrence of oesophageal squamous cell carcinoma is still controversial. Several studies have reported the feasibility and efficacy of concurrent che...

    Wen-Wen Zhang, Yu-Jia Zhu, Han Yang, Qiao-Xuan Wang, **ao-Hui Wang in Scientific Reports (2015)

  10. Article

    Open Access

    TIGAR regulates DNA damage and repair through pentosephosphate pathway and Cdk5-ATM pathway

    Previous study revealed that the protective effect of TIGAR in cell survival is mediated through the increase in PPP (pentose phosphate pathway) flux. However, it remains unexplored if TIGAR plays an important...

    Hong-Pei Yu, Jia-Ming **e, Bin Li, Yi-Hui Sun, Quan-Geng Gao in Scientific Reports (2015)

  11. Article

    Open Access

    MicroRNA expression profiles predict clinical phenotypes and prognosis in chromophobe renal cell carcinoma

    Chromophobe renal cell carcinoma (chRCC) is the third most common subtype of kidney cancers. In the present study, we identified 58 treatment-naïve primary chRCC patients from The Cancer Genome Atlas dataset a...

    Yu-Zheng Ge, Hui **n, Tian-Ze Lu, Zheng Xu, Peng Yu, You-Cai Zhao in Scientific Reports (2015)

  12. Article

    Open Access

    Comparison between 200 mg QD and 100 mg BID oral celecoxib in the treatment of knee or hip osteoarthritis

    This network meta-analysis aimed to investigate the effectiveness and safety of 100 mg BID and 200 mg QD oral celecoxib in the treatment of OA of the knee or hip. PubMed, Embase and Cochrane Library were searc...

    Chao Zeng, Jie Wei, Hui Li, Tuo Yang, Shu-guang Gao, Yu-sheng Li in Scientific Reports (2015)

  13. Article

    Open Access

    Identification of new susceptibility loci for IgA nephropathy in Han Chinese

    IgA nephropathy (IgAN) is one of the most common primary glomerulonephritis. Previously identified genome-wide association study (GWAS) loci explain only a fraction of disease risk. To identify novel susceptib...

    Ming Li, Jia-Nee Foo, **-Quan Wang, Hui-Qi Low, Xue-Qing Tang in Nature Communications (2015)

  14. No Access

    Article

    The cell cycle regulator 14-3-3σ opposes and reverses cancer metabolic reprogramming

    Extensive reprogramming of cellular energy metabolism is a hallmark of cancer. Despite its importance, the molecular mechanism controlling this tumour metabolic shift remains not fully understood. Here we show...

    Liem Phan, **-Chieh Chou, Guermarie Velazquez-Torres in Nature Communications (2015)

  15. Article

    Open Access

    Highlighting Indication of extracorporeal membrane oxygenation in endocrine emergencies

    Extracorporeal membrane oxygenation (ECMO) has been repeatedly used to rescue patients with cardiopulmonary arrest. However, its clinical utility in endocrine emergencies remains unclear. Herein, we describe a...

    Anne Chao, Chih-Hsien Wang, Hao-Chun You, Nai-Kwoun Chou, Hsi-Yu Yu in Scientific Reports (2015)

  16. Article

    Open Access

    Higher blood hematocrit predicts hyperuricemia: a prospective study of 62897 person-years of follow-up

    This prospective study aimed to investigate the relationship between higher hematocrit (Hct) level and hyperuricemia (HU) incidence. A total of 27540 subjects were included. Baseline Hct was classified into fo...

    Chao Zeng, Jie Wei, Tuo Yang, Hui Li, Wen-feng **ao, Wei Luo in Scientific Reports (2015)

  17. Article

    Open Access

    Serum amyloid-beta levels are increased in patients with obstructive sleep apnea syndrome

    A critical link between amyloid-beta (Aβ) and hypoxia has been demonstrated in in vitro and animal studies but has not yet been proven in humans. Obstructive sleep apnea syndrome (OSAS) is a common disorder that ...

    **an-Le Bu, Yu-Hui Liu, Qing-Hua Wang, Shu-Sheng Jiao, Fan Zeng in Scientific Reports (2015)

  18. Article

    Open Access

    Stem cell transplantation therapy in Parkinson’s disease

    Ineffective therapeutic treatments and inadequate repair ability in the central nervous system are disturbing problems for several neurological diseases. Fortunately, the development of clinically applicable p...

    Mu-Hui Fu, Chia-Ling Li, Hsiu-Lien Lin, Pei-Chun Chen, Marcus J. Calkins in SpringerPlus (2015)

  19. Article

    Open Access

    Can silicon carbide serve as a saturable absorber for passive mode-locked fiber lasers?

    The study presents a novel demonstration of a passively mode-locked erbium-doped fiber laser (EDFL) that is based on a silicon carbide (SixC1−x) saturable absorber. When the C/Si composition ratio is increased to...

    Chih-Hsien Cheng, Yung-Hsiang Lin, Ting-Hui Chen, Hsiang-Yu Chen in Scientific Reports (2015)

  20. Article

    Open Access

    Effectiveness and safety of Glucosamine, chondroitin, the two in combination, or celecoxib in the treatment of osteoarthritis of the knee

    This study aimed to investigate the effectiveness and safety of glucosamine, chondroitin, the two in combination, or celecoxib in the treatment of knee osteoarthritis (OA). PubMed, Embase and Cochrane Library ...

    Chao Zeng, Jie Wei, Hui Li, Yi-lun Wang, Dong-xing **e, Tuo Yang in Scientific Reports (2015)

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