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Article
TOPK Inhibition Enhances the Sensitivity of Colorectal Cancer Cells to Radiotherapy by Reducing the DNA Damage Response
Abnormal expression of T-lymphokine-activated killer cell-originated protein kinase (TOPK) was reported to be closely related to the resistance of prostate cancer to radiotherapy and to targeted drug resistanc...
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Article
Open AccessTargeting pro-inflammatory T cells as a novel therapeutic approach to potentially resolve atherosclerosis in humans
Atherosclerosis (AS), a leading cause of cardio-cerebrovascular disease worldwide, is driven by the accumulation of lipid contents and chronic inflammation. Traditional strategies primarily focus on lipid redu...
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Article
Histological Features of Uterine Myometrial Dysfunction: Possible Involvement of Localized Inflammation
The latest perspective suggests that elevated levels of inflammation and cytokines are implicated in atonic postpartum hemorrhage. Lipopolysaccharide (LPS) has been widely used to induce inflammation in animal...
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Article
Open AccessDynamic changes in RNA m6A and 5 hmC influence gene expression programs during macrophage differentiation and polarisation
RNA modifications are essential for the establishment of cellular identity. Although increasing evidence indicates that RNA modifications regulate the innate immune response, their role in monocyte-to-macropha...
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Article
Open AccessAuthor Correction: Amyloid modifier SERF1a interacts with polyQ-expanded huntingtin-exon 1 via helical interactions and exacerbates polyQ-induced toxicity
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Article
Bismuth-Containing Quadruple Therapy for Helicobacter pylori Eradication: A Randomized Clinical Trial of 10 and 14 Days
Bismuth-containing quadruple therapy is the first-line treatment for eradicating Helicobacter pylori (H. pylori). The optimal duration for H. pylori eradication using bismuth-containing quadruple therapy remains ...
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Article
Application of Bionic Technology in Marine Cruise Equipment: Research Progress and Development Trends
This article provides an overview of the application of bionic technology in marine cruising equipment, discussing its research progress and future development trends. Marine cruising is a crucial means of gai...
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Article
Open AccessThe rise of baobab trees in Madagascar
The baobab trees (genus Adansonia) have attracted tremendous attention because of their striking shape and distinctive relationships with fauna1. These spectacular trees have also influenced human culture, inspir...
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Article
Open AccessResidential mobility and liver cancer risk: findings from a prospective cohort study in Chinese women
Residential mobility is believed to influence the occurrence and development of cancer; however, the results are inconclusive. Furthermore, limited studies have been conducted on Asian populations. This study ...
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Article
Open AccessMini-dose methotrexate combined with methylprednisolone for the initial treatment of acute GVHD: a multicentre, randomized trial
There is an urgent unmet need for effective initial treatment for acute graft-versus-host disease (aGVHD) adding to the standard first-line therapy with corticosteroids after allogeneic haematopoietic stem cel...
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Article
Open AccessDiet and lifestyle behaviours simultaneously act on frailty: it is time to move the threshold of frailty prevention and control forward
To analyse the association among the simultaneous effects of dietary intake, daily life behavioural factors, and frailty outcomes in older Chinese women, we predicted the probability of maintaining physical ro...
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Article
Cooperative effect of citric acid and pyrite on the slow-release of silicon from coal gangue and the stabilization of arsenic: Implications for soil remediation
The application of coal gangue as a soil amendment shows promise in increasing silicon availability, potentially serving as a silicon fertilizer in agriculture. However, the rapid release of silicon from coal ...
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Article
COVID-19 vaccination affects short-term anti-coagulation levels in warfarin treatment
Vaccines against SARS-CoV-2 have been recommended across the world, yet no study has investigated whether COVID-19 vaccination influences short-term warfarin anti-coagulation levels. Patients on stable warfari...
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Article
Open AccessIntrinsic and extrinsic actions of human neural progenitors with SUFU inhibition promote tissue repair and functional recovery from severe spinal cord injury
Neural progenitor cells (NPCs) derived from human pluripotent stem cells(hPSCs) provide major cell sources for repairing damaged neural circuitry and enabling axonal regeneration after spinal cord injury (SCI)...
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Article
Open AccessReductive soil disinfestation by mixing carbon nanotubes and mushroom residues to mitigate the continuous crop** obstacles for Lilium Brownii
Reductive soil disinfestation can effectively alleviate continuous crop** obstacles. The effects of mixing mushroom residues and carbon nanotubes on the structure and function of soil microbial communities a...
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Article
Efficacy of growth factor gene–modified stem cells for motor function after spinal cord injury in rodents: a systematic review and meta‑analysis
The efficacy of growth factor gene–modified stem cells in treating spinal cord injury (SCI) remains unclear. This study aims to evaluate the effectiveness of growth factor gene–modified stem cells in restoring...
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Article
Genetic architectures of cerebral ventricles and their overlap with neuropsychiatric traits
The cerebral ventricles are recognized as windows into brain development and disease, yet their genetic architectures, underlying neural mechanisms and utility in maintaining brain health remain elusive. Here ...
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Chapter and Conference Paper
CFD Simulation of the Micro-mechanism of Water Trap** Effect in Carbonate Gas Reservoirs
Water invasion is an important factor restricting the development benefit of natural gas reservoirs with water. Water trap** effect accompanied by water invasion will reduce gas well productivity, shorten th...
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Article
Open Access50 Years of quantum chromodynamics
Quantum Chromodynamics, the theory of quarks and gluons, whose interactions can be described by a local SU(3) gauge symmetry with charges called “color quantum numbers”, is reviewed; the goal of this review is...
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Article
The new X-ray imaging and biomedical application beamline BL13HB at SSRF
A new X-ray imaging and biomedical application beamline (BL13HB) has been implemented at the Shanghai Radiation Synchrotron Facility (SSRF) as an upgrade to the old X-ray imaging and biomedical application bea...
