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  1. No Access

    Chapter

    Personalized Immuno-Oncology with Immunodeficiency Mouse Models

    In the past decades, cancer therapies are evolved from a non-specific approach to a precise and accurate therapy. Precision (or personalized) cancer therapy, in which a patient’s own tumor information is used ...

    Jui-Ling Wang, Wen-Hui Ma, Tak-Wah Wong… in Cancer Research: An Interdisciplinary Appr… (2023)

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    Article

    The TRIMCyp genotype in four species of macaques in China

    The tripartite motif protein (TRIM)5α/CypA fusion protein TRIMCyp in Old World monkeys is generally considered unable to restrict HIV-1 replication. Monkeys with TRIMCyp can serve as a unique animal model for ...

    Chang-Qing Yu, Lei Na, **ao-Ling Lv, Jian-Dong Liu, **ao-Ming Liu… in Immunogenetics (2013)

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    Article

    FcεRIα gene –18483A>C polymorphism affects transcriptional activity through YY1 binding

    Three frequent genetic polymorphisms in the human high-affinity IgE receptor α-subunit (FcεRIα) were shown to be associated with allergic disorders and/or total serum IgE levels in allergic patients. Two of th...

    Daniel P. Potaczek, Keiko Maeda, Qing-Hui Wang, Nobuhiro Nakano… in Immunogenetics (2009)

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    Article

    Suppressive effect of Elf-1 on FcεRI α-chain expression in primary mast cells

    The high-affinity receptor for immunoglobulin E (IgE), FcεRI, is specifically expressed in mast cells and basophils and plays a key role in IgE-mediated allergic reactions. The transcription factor Elf-1 has b...

    Qing-hui Wang, Chiharu Nishiyama, Nobuhiro Nakano, Naomi Shimokawa… in Immunogenetics (2008)

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    Article

    Identification and expression analysis of alternatively spliced isoforms of human interleukin-23 receptor gene in normal lymphoid cells and selected tumor cells

    Interleukin 23 (IL-23) is a new member of the IL-12 family that plays a critical role in promoting the proliferation of memory T helper 1 cells. The heterodimerized IL-23 receptor is composed of a shared IL-12...

    **ang-Yue Zhang, Hai-**g Zhang, Yun Zhang, Ying-Jie Fu, Jie He… in Immunogenetics (2006)