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Article
miR-34a/TAN1/CREB Axis Engages in Alleviating Oligodendrocyte Trophic Factor-Induced Myelin Repair Function and Astrocyte-Dependent Neuroinflammation in the Early Stages of Alzheimer's Disease: The Anti-Neurodegenerative Effect of Treadmill Exercise
Reduced myelin stability observed in the early stages of Alzheimer's disease leads to spatial learning and memory impairment. Exercise has been shown to protect nerves, reduce the risk of Alzheimer's disease, ...
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Article
Measurement of Br(n,γ) cross sections up to stellar s-process temperatures at the CSNS Back-n
The neutron capture cross sections ( \({n,\gamma }\) n , ...
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Article
Open AccessThe Presence of Diabetes Mellitus or Pre-diabetes Mellitus Increases Mortality from Heart Disease in a Taiwanese Population: A 10-year Follow-Up Study
We evaluated hyperglycemia-associated mortality in the Taiwanese population by conducting a 10-year retrospective cohort study. Methods: From 2007 to 2017, all participants, regardless of their age or underlyi...
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Article
Open AccessThrombin induces ACSL4-dependent ferroptosis during cerebral ischemia/reperfusion
Ischemic stroke represents a significant danger to human beings, especially the elderly. Interventions are only available to remove the clot, and the mechanism of neuronal death during ischemic stroke is still...
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Article
Effects of soil shrinkage in permanent gullies formation: The case of Benggang erosion in the granite area of southern China
Soil shrinkage is an important factor in slope destabilization in granitic areas, which is also one of the most important conditions for the formation of permanent gullies. This study explored the effect of so...
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Article
Insulin Resistance in Polycystic Ovary Syndrome Improved by Chinese Medicine Dingkun Pill (定坤丹): A Randomized Controlled Clinical Trial
To assess the efficacy and safety of the Chinese medicine Dingkun Pill (定坤丹, DKP) on insulin resistance in women with polycystic ovary syndrome (PCOS).
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Article
Open AccessTRIM44 activates the AKT/mTOR signal pathway to induce melanoma progression by stabilizing TLR4
There is growing evidence that tripartite motif-containing protein 44 (TRIM44) plays crucial role in tumor development. However, the underlying mechanism of this deubiquitinating enzyme remains unclear.
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Article
Blockage of the NLRP3 inflammasome by MCC950 improves anti-tumor immune responses in head and neck squamous cell carcinoma
The NLRP3 inflammasome is a critical innate immune pathway responsible for producing active interleukin (IL)-1β, which is associated with tumor development and immunity. However, the mechanisms regulating the ...
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Article
Open AccessSecretory laccase 1 in Bemisia tabaci MED is involved in whitefly-plant interaction
The whitefly Bemisia tabaci is a phloem-feeding pest that lives predominantly on herbaceous species and causes serious damage to hosts. Whitefly saliva is thought to contain proteins that modulate plant defences ...
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Article
Expression of VISTA correlated with immunosuppression and synergized with CD8 to predict survival in human oral squamous cell carcinoma
V-domain Ig suppressor of T cell activation (VISTA), a novel immune checkpoint regulatory molecule, suppresses T cell mediated immune responses. The aim of the present study was to profile the immunological ex...
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Article
Sodium P-Aminosalicylic Acid Improved Manganese-Induced Learning and Memory Dysfunction via Restoring the Ultrastructural Alterations and γ-Aminobutyric Acid Metabolism Imbalance in the Basal Ganglia
Excessive intake of manganese (Mn) may cause neurotoxicity. Sodium para-aminosalicylic acid (PAS-Na) has been used successfully in the treatment of Mn-induced neurotoxicity. The γ-aminobutyric acid (GABA) is r...
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Article
Open Access31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two
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Article
Expression of LC3, LAMP2, KEAP1 and NRF2 in Salivary Adenoid Cystic Carcinoma
Salivary Adenoid Cystic Carcinoma (SACC) is a tumor characterized by inevitable local progression and terminal hematogenous metastasis. This study aimed to investigate the expression of LC3, LAMP2, KEAP1 and N...
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Article
Fibrin sealant before wound closure in total knee arthroplasty reduced blood loss: a meta-analysis
Fibrin sealant (FS) comprises a mixture of fibrinogen and thrombin that controls bleeding, reduces blood transfusions, improves tissue healing and shortens postoperative recovery time after various surgical pr...
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Article
Tectonic mechanism of the Suining (Ms5.0) earthquake, center of Sichuan Basin, China
On Jan. 31 of 2010, the Suining earthquake occurred at Suining City whch is located the center of Sichuan Basin. It is unusual for the strong earthquake to occur at the center of Sichuan Basin with a stable ge...
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Article
Development of Continuous Casting Technology of Electrical Steel and New Products
The development of continuous casting technology of electrical steel was analyzed. The technologies and products characteristics of conventional continuous casting, thin slab continuous casting and rolling, mi...
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Article
High-Altitude Windborne Transport of Helicoverpa armigera (Lepidoptera: Noctuidae) in Mid-Summer in Northern China
The high-altitude windborne transport of the second-generation moths of Helicoverpa armigera (Hübner) was observed with radar in July 2001 and 2002 at Langfang, Hebei province, China. Moths of local populations t...
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Article
CO2 Hydrogenation to Methanol Over Cu/ZnO/Al2O3 Catalysts Prepared by a Novel Gel-Network-Coprecipitation Method
A novel gel-network-coprecipitation process has been developed to prepare ultrafine Cu/ZnO/Al2O3 catalysts for methanol synthesis from CO2 hydrogenation. It is demonstrated that the gel-network-coprecipitation me...
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Article
Novel Heterogeneous W-Doped MCM-41 Catalyst for Highly Selective Oxidation of Cyclopentene to Glutaraldehyde by Aqueous H2O2
W-doped MCM-41 (W-MCM-41) has been reported as a novel heterogeneous catalyst for the selective oxidation of cyclopentene to prepare glutaraldehyde with environmentally benign aqueous hydrogen peroxide. It is ...
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Article
Characterization of High-Surface-Area Zirconia Aerogel Synthesized from Combined Alcohothermal and Supercritical Fluid Drying Techniques
Thermally stable tetragonal zirconia aerogel with a high surface area can be obtained by a novel alcohothermal route, followed by the supercritical fluid drying technique. In addition, a cheaper inorganic salt...
