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20,097 Result(s)
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Free Amino-acids of Isolated Calf Thymus Nuclei
CALF thymus nuclei prepared by the sucrose–calcium chloride method of Allfrey et al.1 are remarkably biochemically active, as judged by the incorporation of labelled amino-acids into the nuclear proteins1,2. Such...
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Breakdown Rate of Serum 7S γ-Globulins in Mice
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Polyamide Layer Chromatography of some Synthetic Food Colours
RECENT developments in the preparation, of polyamide layers in our laboratory have facilitated the application of polyamide layer chromatography to many kinds of compounds besides phenolic compounds; for examp...
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Structure, sequence and expression of the hepatitis delta (δ) viral genome
Nature 323, 508–514 (1986). A GUANOSINE residue was omitted from the nucleotide sequence of the hepatitis 8 viral (HDV) genomic RNA between residues 1,113 and 1,114 (Figs 4 and 5). HDV RNA therefore consists o...
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Plight of Wei **gsheng
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Straight talking
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Non-haemolytic β-amino-acid oligomers
Pathogenic bacteria are becoming increasingly resistant to common antibiotics, stimulating an intensive search for new ones. Knowing that a class of medium-sized peptides (magainins1) are widely used by host orga...
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Correction: The limits of selection during maize domestication
Nature 398 , 236 - 239 (1999 ). The primers used for PCR of the 3′ portion of tb1 amplified a duplicate locus (tb1 homeologue) in two samples (11 and 16). Inclusion of these homeologous sequences caused π to r...
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Seeking, sometimes finding, that elusive chemistry
Despite all the discipline's achievements, opinion is divided as to whether chemistry is getting the recognition it deserves — and needs — in order to keep attracting new talent.
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Statistics hide impact of non-English journals
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Correction: Corrigendum: Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2
Nature 404, 298–302 (2000). In this Letter, we numbered some nucleotides for the upstream region of the reelin gene incorrectly. The Reelin-luc construct contains an upstream region of the reelin gene correspo...
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Open AccessUnique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing
Leptospirosis is a widely spread disease of global concern. Infection causes flu-like episodes with frequent severe renal and hepatic damage, such as haemorrhage and jaundice. In more severe cases, massive pul...
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Open AccessThe genome sequence of the filamentous fungus Neurospora crassa
Neurospora crassa is a central organism in the history of twentieth-century genetics, biochemistry and molecular biology. Here, we report a high-quality draft sequence of the N. crassa genome. The approximately 4...
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Modelling disease outbreaks in realistic urban social networks
Most mathematical models for the spread of disease use differential equations based on uniform mixing assumptions1 or ad hoc models for the contact process2,3,4. Here we explore the use of dynamic bipartite graph...
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Open AccessThe genome of the protist parasite Entamoeba histolytica
The genome sequence of the pathogen Entamoeba histolytica is reported this week. E. histolytica causes amoebiasis, the second most deadly protozoan disease after malaria. The genome contains adaptations shared wi...
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Open AccessGenome sequencing in microfabricated high-density picolitre reactors
The proliferation of large-scale DNA-sequencing projects in recent years has driven a search for alternative methods to reduce time and cost. Here we describe a scalable, highly parallel sequencing system with...
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Correction: Corrigendum: Genome sequencing in microfabricated high-density picolitre reactors
Nature 437, 376–380 (2005)10.1038/nature03959 The following were omitted from the original author listing: Alex de Winter, James Drake, Robin Forte, Steve Hutchinson, William L. Lee, Michael Reifler and David ...
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Gene-function wiki would let biologists pool worldwide resources
A microarray experiment or BLAST search can turn up thousands of gene names, but the average biologist has little notion as to what most of them do, and has to start ploughing through the literature. Time for ...
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Correction: Corrigendum: Genome sequencing in microfabricated high-density picolitre reactors
Nature 437, 376–380 (2005) In this paper, the second name of Chun Heen Ho was misspelled as He. In the earlier Corrigendum (Nature 439, 502; 2006) the surnames of Stephen K. Hutchison and Brian C. Godwin were ...
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Open AccessThe draft genome of the transgenic tropical fruit tree papaya (Carica papaya Linnaeus)
In the early 1990s an outbreak of papaya ringspot virus (PRSV) in the papaya groves in the Puna district of Hawaii caused severe damage to an important crop. Since then, the planting of two transgenic cultivar...