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  1. Article

    Open Access

    Refined risk stratification helps guiding transplantation choice in adult BCR::ABL1-positive acute lymphoblastic leukemia

    Cheng Wang, Jianfeng Li, Weiyang Liu, Lingling Zhao, Han Yan… in Blood Cancer Journal (2024)

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  2. Article

    Open Access

    Real-world advantage and challenge of post-autologous stem cell transplantation MRD negativity in high-risk patients with double-hit multiple myeloma

    Autologous stem-cell transplantation (ASCT) remains a beneficial approach for patients with newly diagnosed multiple myeloma (NDMM) in the age of novel therapeutic agents. Nevertheless, limited real-world data...

    Yi Tao, Shiwei **, Dan Yang, Mengmeng Pan, Wanyan Ouyang, Yuanfang Liu… in BMC Cancer (2024)

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  3. Article

    Open Access

    Downregulation of SMIM3 inhibits growth of leukemia via PI3K-AKT signaling pathway and correlates with prognosis of adult acute myeloid leukemia with normal karyotype

    Acute myeloid leukemia (AML) patients with normal karyotype (NK-AML) have significant variabilities in outcomes. The European Leukemia Net stratification system and some prognostic models have been used to eva...

    Yu Liu, Yufei Chen, Yajun Liu, Mengya Li, Yu Zhang… in Journal of Translational Medicine (2022)

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  4. No Access

    Article

    Claudin-1/4 as directly target gene of HIF-1α can feedback regulating HIF-1α by PI3K-AKT-mTOR and impact the proliferation of esophageal squamous cell though Rho GTPase and p-JNK pathway

    Immunohistochemical microarray comprising 80 patients with esophageal squamous cell carcinoma (ESCC) and discovered that the expression of CLDN1 and CLDN4 were significantly higher in cancer tissues compared to p...

    Hong Liu, Zhancheng Zhang, Shenli Zhou, **anfang Liu, Guodong Li… in Cancer Gene Therapy (2022)

  5. Article

    Open Access

    The emerging landscape of exosomal CircRNAs in solid cancers and hematological malignancies

    Circular RNAs (circRNAs) are a type of recently discovered noncoding RNA. They exert their biological functions by competitively binding to microRNAs (miRNAs) as miRNA sponges, promoting gene transcription and...

    Qinfeng Zhou, Dacheng **e, Rong Wang, Lianfang Liu, Yue Yu… in Biomarker Research (2022)

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  6. Article

    Publisher Correction: K33-linked polyubiquitination of Zap70 by Nrdp1 controls CD8+ T cell activation

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Ming** Yang, Taoyong Chen, Xuelian Li, Zhou Yu, Songqing Tang… in Nature Immunology (2020)

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  7. No Access

    Article

    Mutation of a histidine-rich calcium-binding-protein gene in wheat confers resistance to Fusarium head blight

    Head or ear blight, mainly caused by Fusarium species, can devastate almost all staple cereal crops (particularly wheat), resulting in great economic loss and imposing health threats on both human beings and live...

    Guoqiang Li, Jiyang Zhou, Haiyan Jia, Zhongxia Gao, Min Fan, Yanjun Luo… in Nature Genetics (2019)

  8. No Access

    Article

    Tumor-educated B cells selectively promote breast cancer lymph node metastasis by HSPA4-targeting IgG

    Primary tumors may create the premetastatic niche in secondary organs for subsequent metastasis. Humoral immunity contributes to the progression of certain cancers, but the roles of B cells and their derived a...

    Yan Gu, Yanfang Liu, Li Fu, Lili Zhai, Jie Zhu, Yanmei Han… in Nature Medicine (2019)

  9. No Access

    Article

    K33-linked polyubiquitination of Zap70 by Nrdp1 controls CD8+ T cell activation

    The molecular details of the control of TCR signaling are still being determined. Cao and colleagues report that the E3 ligase Nrdp1 negatively regulates activity of the signaling kinase Zap70 selectively in CD8+

    Ming** Yang, Taoyong Chen, Xuelian Li, Zhou Yu, Songqing Tang… in Nature Immunology (2015)

  10. Article

    Open Access

    Interaction of myelin basic protein with cytoskeletal and signaling proteins in cultured primary oligodendrocytes and N19 oligodendroglial cells

    The classic myelin basic protein (MBP) isoforms are intrinsically-disordered proteins of 14–21.5 kDa in size arising from the Golli (Gene in the Oligodendrocyte Lineage) gene complex, and are responsible for form...

    Joan M Boggs, Lopamudra Homchaudhuri, Godha Ranagaraj, Yuanfang Liu… in BMC Research Notes (2014)

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