34 Result(s)

Article

Small extracellular vesicles from young plasma reverse age-related functional declines by improving mitochondrial energy metabolism

Recent investigations into heterochronic parabiosis have unveiled robust rejuvenating effects of young blood on aged tissues. However, the specific rejuvenating mechanisms remain incompletely elucidated. Here ...

**aorui Chen, Yang Luo, Qing Zhu, **gzi Zhang, Huan Huang, Yansheng Kan… in Nature Aging (2024)

Article

Identification of key genes controlling monoterpene biosynthesis of Citral-type Cinnamomum bodinieri Levl. Based on transcriptome and metabolite profiling

The citral-type is the most common chemotype in Cinnamomum bodinieri Levl (C. bodinieri), which has been widely used in the daily necessities, cosmetics, biomedicine, and aromatic areas due to their high citral c...

Qingyan Ling, Beihong Zhang, Yanbo Wang, Zufei **ao, Jiexi Hou… in BMC Genomics (2024)

Article

Galectin-3 is involved in inflammation and fibrosis in arteriogenic erectile dysfunction via the TLR4/MyD88/NF-κB pathway

Galectin-3 (Gal-3) is a multifunctional protein that has been linked to fibrosis and inflammation in the cardiovascular system. In this study, we examined the impact of Gal-3 on inflammation and fibrosis in pa...

Guanbo Wang, Ruiyu Li, Chen Feng, Kefan Li, Shuai Liu, Qiang Fu in Cell Death Discovery (2024)

Article

ANKRD29, as a new prognostic and immunological biomarker of non–small cell lung cancer, inhibits cell growth and migration by regulating MAPK signaling pathway

The predominant cancer-related deaths worldwide are caused by lung cancer, particularly non-small cell lung cancer (NSCLC), despite the fact that numerous therapeutic initiatives have been devised to improve t...

Hanqing Zhao, Yanbo Wang, Yaomei He, Peng Zhang, Cheng Zeng, Tongxuan Du… in Biology Direct (2023)

Article

Asymmetric subgenomic chromatin architecture impacts on gene expression in resynthesized and natural allopolyploid Brassica napus

Although asymmetric subgenomic epigenetic modification and gene expression have been revealed in the successful establishment of allopolyploids, the changes in chromatin accessibility and their relationship wi...

Zeyu Li, Mengdi Li, Jianbo Wang in Communications Biology (2022)

Article

microRNAs in aged sperm confer psychiatric symptoms to offspring through causing the dysfunction of estradiol signaling in early embryos

Gaoli Liang, **aoju Zhu, Zixuan Zhang, Li Chen, Hui** Feng, Shoubin Zhan… in Cell Discovery (2022)

Article

Genome-wide association studies of yield-related traits in high-latitude japonica rice

Heilongjiang Province is a high-quality japonica rice cultivation area in China. One in ten bowls of Chinese rice is produced here. Increasing yield is one of the main aims of rice production in this area. How...

Guomin Zhang, Rongsheng Wang, Juntao Ma, Hongru Gao, Lingwei Deng… in BMC Genomic Data (2021)

Article

In vivo self-assembled small RNAs as a new generation of RNAi therapeutics

RNAi therapy has undergone two stages of development, direct injection of synthetic siRNAs and delivery with artificial vehicles or conjugated ligands; both have not solved the problem of efficient in vivo siR...

Zheng Fu, **ang Zhang, **nyan Zhou, Uzair Ur-Rehman, Mengchao Yu… in Cell Research (2021)

Article

SIDT1-dependent absorption in the stomach mediates host uptake of dietary and orally administered microRNAs

Dietary microRNAs have been shown to be absorbed by mammals and regulate host gene expression, but the absorption mechanism remains unknown. Here, we show that SIDT1 expressed on gastric pit cells in the stoma...

Qun Chen, Fan Zhang, Lei Dong, Huimin Wu, Jie Xu, Hanqin Li, ** Wang… in Cell Research (2021)

Article

Hypomethylation of PlncRNA-1 promoter enhances bladder cancer progression through the miR-136-5p/Smad3 axis

Apart from being potential prognostic biomarkers and therapeutic targets, long non-coding RNAs (lncRNAs) modulate the development and progression of multiple cancers. PlncRNA-1 is a newly discovered lncRNA tha...

Weiting Kang, Qiang Wang, Yun Dai, Hanbo Wang, Muwen Wang, ** Wang… in Cell Death & Disease (2020)

Article

Decreased HD-MIR2911 absorption in human subjects with the SIDT1 polymorphism fails to inhibit SARS-CoV-2 replication

Zhen Zhou, Yu Zhou, **a-Ming Jiang, Yanbo Wang, ** Chen, Gengfu **ao… in Cell Discovery (2020)

Article

Homoeolog expression bias and expression level dominance (ELD) in four tissues of natural allotetraploid Brassica napus

Allopolyploidy is widespread in angiosperms, and they can coordinate two or more different genomes through genetic and epigenetic modifications to exhibit stronger vigor and adaptability. To explore the change...

Mengdi Li, Ruihua Wang, **aoming Wu, Jianbo Wang in BMC Genomics (2020)

Article

circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma

Circular RNAs (circRNAs) have been identified play a vital role in various different types of cancer via sponging miRNAs (microRNAs). However, their role in lung adenocarcinoma (LUAD) remains largely unclear. ...

JunFeng Wang, XuHai Zhao, YanBo Wang, FengHai Ren, DaWei Sun… in Cell Death & Disease (2020)

Article

Genome-wide identification and analysis of the WUSCHEL-related homeobox (WOX) gene family in allotetraploid Brassica napus reveals changes in WOX genes during polyploidization

WUSCHEL-related homeobox (WOX) genes encoding plant-specific homeobox (HB) transcription factors play important roles in the growth and development of plants. To date, WOX genes has been identified and analyzed i...

Mengdi Li, Ruihua Wang, Zhengyi Liu, **aoming Wu, Jianbo Wang in BMC Genomics (2019)

Article

Identification of lncRNAs involved in rice ovule development and female gametophyte abortion by genome-wide screening and functional analysis

As important female reproductive tissues, the rice (Oryza sativa L.) ovule and female gametophyte is significant in terms of their fertility. Long noncoding RNAs (lncRNAs) play important and wide-ranging roles in...

Helian Liu, Ruihua Wang, Bigang Mao, Bingran Zhao, Jianbo Wang in BMC Genomics (2019)

Article

Species–habitat associations in an old-growth temperate forest in northeastern China

Species coexistence mechanisms and maintenance of biodiversity have long been considered important components of community ecology research. As one of the important mechanisms, species coexistence theory based...

Qi Liu, Lianzhu Bi, Guohua Song, Quanbo Wang, Guangze ** in BMC Ecology (2018)