89 Result(s)

Article

Characteristics of duplicated gene expression and DNA methylation regulation in different tissues of allopolyploid Brassica napus

Plant polyploidization increases the complexity of epigenomes and transcriptional regulation, resulting in genome evolution and enhanced adaptability. However, few studies have been conducted on the relationsh...

Weiqi Sun, Mengdi Li, Jianbo Wang in BMC Plant Biology (2024)

Article

Mechanical models and measurement methods of solid stress in tumors

In addition to genetic mutations, biomechanical factors also affect the structures and functions of the tumors during tumor growth, including solid stress, interstitial fluid pressure, stiffness, and microarch...

Yingwei Bi, Jiacheng **, Rui Wang, Yuxin Liu… in Applied Microbiology and Biotechnology (2024)

Article

Small extracellular vesicles from young plasma reverse age-related functional declines by improving mitochondrial energy metabolism

Recent investigations into heterochronic parabiosis have unveiled robust rejuvenating effects of young blood on aged tissues. However, the specific rejuvenating mechanisms remain incompletely elucidated. Here ...

**aorui Chen, Yang Luo, Qing Zhu, **gzi Zhang, Huan Huang, Yansheng Kan… in Nature Aging (2024)

Article

Identification of key genes controlling monoterpene biosynthesis of Citral-type Cinnamomum bodinieri Levl. Based on transcriptome and metabolite profiling

The citral-type is the most common chemotype in Cinnamomum bodinieri Levl (C. bodinieri), which has been widely used in the daily necessities, cosmetics, biomedicine, and aromatic areas due to their high citral c...

Qingyan Ling, Beihong Zhang, Yanbo Wang, Zufei **ao, Jiexi Hou… in BMC Genomics (2024)

Article

Galectin-3 is involved in inflammation and fibrosis in arteriogenic erectile dysfunction via the TLR4/MyD88/NF-κB pathway

Galectin-3 (Gal-3) is a multifunctional protein that has been linked to fibrosis and inflammation in the cardiovascular system. In this study, we examined the impact of Gal-3 on inflammation and fibrosis in pa...

Guanbo Wang, Ruiyu Li, Chen Feng, Kefan Li, Shuai Liu, Qiang Fu in Cell Death Discovery (2024)

Article

Reciprocal regulation of TWIST1 and OGT determines the decitabine efficacy in MDS/AML

Chemoresistance poses a significant impediment to effective treatment strategies for myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). Our previous study unveiled that oncogene TWIST1 interacte...

Hongjiao Li, Yi Wang, Shuang Feng, Kai**g Chang… in Cell Communication and Signaling (2023)

Article

ANKRD29, as a new prognostic and immunological biomarker of non–small cell lung cancer, inhibits cell growth and migration by regulating MAPK signaling pathway

The predominant cancer-related deaths worldwide are caused by lung cancer, particularly non-small cell lung cancer (NSCLC), despite the fact that numerous therapeutic initiatives have been devised to improve t...

Hanqing Zhao, Yanbo Wang, Yaomei He, Peng Zhang, Cheng Zeng, Tongxuan Du… in Biology Direct (2023)

Article

Transcriptomic Analysis Reveals That Exogenous Indole-3-Butyric Acid Affects the Rooting Process During Stem Segment Culturing of Cinnamomum camphora Linalool Type

Cinnamomum camphora linalool type (C. camphora linalool type) is an economically important plant that contains abundant linalool. To explore the optimal concentration of exogenously applied indole-3-butyric acid ...

Zufei **ao, Beihong Zhang, Yanbo Wang, Feng Li… in Plant Molecular Biology Reporter (2022)

Article

WY-14643 attenuates lipid deposition via activation of the PPARα/CPT1A axis by targeting Gly335 to inhibit cell proliferation and migration in ccRCC

Histologically, cytoplasmic deposits of lipids and glycogen are common in clear cell renal cell carcinoma (ccRCC). Owing to the significance of lipid deposition in ccRCC, numerous trials targeting lipid metabo...

Rui Wang, Jun Zhao, Jiacheng **, Yun Tian, Lan Lan… in Lipids in Health and Disease (2022)

Article

Asymmetric subgenomic chromatin architecture impacts on gene expression in resynthesized and natural allopolyploid Brassica napus

Although asymmetric subgenomic epigenetic modification and gene expression have been revealed in the successful establishment of allopolyploids, the changes in chromatin accessibility and their relationship wi...

Zeyu Li, Mengdi Li, Jianbo Wang in Communications Biology (2022)

Article

The small GTPase BcSec4 is involved in conidiophore development, membrane integrity, and autophagy in Botrytis cinerea

Small GTPases of the Rab family play important roles in membrane trafficking and autophagy. Previous studies have shown that the small GTPase Sec4 is involved in vegetative growth, protein secretion, and patho...

Guanbo Wang, Jian Zou, Yadi Wang, Wenxing Liang, Delong Li in Phytopathology Research (2022)

Article

microRNAs in aged sperm confer psychiatric symptoms to offspring through causing the dysfunction of estradiol signaling in early embryos

Gaoli Liang, **aoju Zhu, Zixuan Zhang, Li Chen, Hui** Feng, Shoubin Zhan… in Cell Discovery (2022)

Article

The impacts of allopolyploidization on Methyl-CpG-Binding Domain (MBD) gene family in Brassica napus

Polyploidization promotes species formation and is widespread in angiosperms. Genome changes dramatically bring opportunities and challenges to plants after polyploidy. Methyl-CpG-Binding Domain (MBD) proteins...

Yafang **ao, Mengdi Li, Jianbo Wang in BMC Plant Biology (2022)