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2,397 Result(s)
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Article
Rhenium-boosted electrocatalytic activity and durability of pyrolytic IrO2 for acidic oxygen evolution
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Article
Open AccessLASSO-derived nomogram for early identification of pediatric monogenic lupus
Monogenic lupus is defined as systemic lupus erythematosus (SLE)/SLE-like patients with either dominantly or recessively inherited pathogenic variants in a single gene with high penetrance. However, because th...
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Article
Open AccessProtein SUMOylation promotes cAMP-independent EPAC1 activation
Protein SUMOylation is a prevalent stress-response posttranslational modification crucial for maintaining cellular homeostasis. Herein, we report that protein SUMOylation modulates cellular signaling mediated ...
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Spatiotemporal Variability and Environmental Controls of Temperature Sensitivity of Ecosystem Respiration across the Tibetan Plateau
Warming-induced carbon loss via ecosystem respiration (Re) is probably intensifying in the alpine grassland ecosystem of the Tibetan Plateau owing to more accelerated warming and the higher temperature sensitivit...
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Open AccessPEX3 promotes regenerative repair after myocardial injury in mice through facilitating plasma membrane localization of ITGB3
The peroxisome is a versatile organelle that performs diverse metabolic functions. PEX3, a critical regulator of the peroxisome, participates in various biological processes associated with the peroxisome. Whe...
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Observation on the Analgesic Effect of Different Doses of a Combination of Esketamine and Dexmedetomidine Administered for Percutaneous Endoscopic Transforaminal Discectomy: A Randomized, Double-Blind Controlled Trial
Percutaneous endoscopic transforaminal discectomy (PETD) is an effective method for treating lumbar disc herniation, and is typically performed under local anesthesia. However, inadequate analgesia during the ...
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Open AccessA pan-KRAS degrader for the treatment of KRAS-mutant cancers
KRAS mutations are highly prevalent in a wide range of lethal cancers, and these mutant forms of KRAS play a crucial role in driving cancer progression and conferring resistance to treatment. While there have bee...
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Open AccessOptimal antiplatelet therapy after revascularization of left subclavian artery during TEVAR
Thoracic endovascular aortic repair (TEVAR) is a minimally invasive technique used to treat type B aortic dissections. Left subclavian artery (LSA) reconstruction is required when treating patients with involv...
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Article
A dual-satellite joint positioning method with improved CTSL for high-speed targets
High-precision space-based optical positioning contributes a lot to high-speed targets’ instantaneous and accurate tracking and trajectory prediction. However, because of the line-of-sight (LOS) calibrated err...
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Article
Effect of additive modification on the product distribution in CO hydrogenation catalyzed by Fe/g-C3N4
The melamine thermal shrinkage method was used to prepare carbon nitride (g-C3N4). Fe/g-C3N4 was obtained by impregnation, and Na, K, and Zn additives were added as modifiers. The CO hydrogenation performances of...
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Open AccessNab-paclitaxel plus platinum versus paclitaxel plus platinum as first-line therapy in patients with metastatic or recurrent cervical cancer
This study aimed to assess the efficacy and safety of nanoparticle albumin-bound paclitaxel (nab-paclitaxel) plus platinum versus paclitaxel plus platinum as first-line therapy in patients with metastatic or r...
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Article
Optimization Modeling for Vibration of Composite Conical Shell Suitable for A Wide Range of Complex Boundaries: Used for Discontinuous Winding Structure
The study of shell vibration also has clear engineering significance and scientific value.
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Open AccessRole of signaling pathways in age-related orthopedic diseases: focus on the fibroblast growth factor family
Fibroblast growth factor (FGF) signaling encompasses a multitude of functions, including regulation of cell proliferation, differentiation, morphogenesis, and patterning. FGFs and their receptors (FGFR) are cr...
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Application of optimized random forest regressors in predicting the maximum principal stress of aseismic tunnel lining
Using flexible dam** technology to improve tunnel lining structure is an emerging method to resist earthquake disasters, and several methods have been explored to predict mechanical response of tunnel lining...
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A novel dual-signal output strategy for POCT of CEA based on a smartphone electrochemical aptasensing platform
A smartphone-based electrochemical aptasensing platform was developed for the point-of-care testing (POCT) of carcinoembryonic antigen (CEA) based on the ferrocene (Fc) and PdPt@PCN-224 dual-signal labeled st...
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Open AccessIdentification and bioinformatics analysis of genes associated with pyroptosis in spinal cord injury of rat and mouse
The mechanism of spinal cord injury (SCI) is highly complex, and an increasing number of studies have indicated the involvement of pyroptosis in the physiological and pathological processes of secondary SCI. H...
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Article
Open AccessLandform and lithospheric development contribute to the assembly of mountain floras in China
Although it is well documented that mountains tend to exhibit high biodiversity, how geological processes affect the assemblage of montane floras is a matter of ongoing research. Here, we explore landform-spec...
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Open AccessDNA methylation variations underlie lettuce domestication and divergence
Lettuce (Lactuca sativa L.) is an economically important vegetable crop worldwide. Lettuce is believed to be domesticated from a single wild ancestor Lactuca serriola and subsequently diverged into two major morp...
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Open AccessThe impact of ZTE-based MR attenuation correction compared to CT-AC in 18F-FBPA PET before boron neutron capture therapy
Tumor-to-normal ratio (T/N) measurement of 18F-FBPA is crucial for patient eligibility to receive boron neutron capture therapy. This study aims to compare the difference in standard uptake value ratios on brain ...
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Existence and Stability of Fuzzy Slightly Altruistic Equilibrium for a Class of Generalized Multiobjective Fuzzy Games
We mainly study the existence, structural stability and robustness of fuzzy slightly altruistic equilibria for a class of generalized multiobjective fuzzy games which are expressed as