1,428 Result(s)
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**an-qing **ong
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Article
Cimifugin Mechanism of Action from Saposhnikovia divaricata in the Treatment of Atopic Dermatitis
The present study aimed to explore the mechanism of action of cimifugin, the primary active ingredient in Saposhnikovia divaricata (Turcz.) Schischk., Apiaceae, in treating atopic dermatitis. BALB/c mice were gro...
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Open AccessTuning electronic structure of metal-free dual-site catalyst enables exclusive singlet oxygen production and in-situ utilization
Develo** eco-friendly catalysts for effective water purification with minimal oxidant use is imperative. Herein, we present a metal-free and nitrogen/fluorine dual-site catalyst, enhancing the selectivity an...
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Low-temperature atomic-level trimming on Ge interfused surface for gate-all-around Si nanosheets transistors
In order to effectively remove the residual Ge atoms at the surface of channel and improve the interfacial characteristic of gate-all-around (GAA) Si nanosheet field effect transistors, a low-temperature atomi...
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ErbB4 deficiency exacerbates olfactory dysfunction in an early-stage Alzheimer’s disease mouse model
Olfactory dysfunction is increasingly recognized as an early indicator of Alzheimer’s disease (AD). Aberrations in GABAergic function and the excitatory/inhibitory (E/I) balance within the olfactory bulb (OB) ...
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Upcycling waste sewage sludge into superior single-atom Fenton-like catalyst for sustainable water purification
The worldwide generation of waste sludge emanating from municipal wastewater treatment plants amounts to 80–90 million tons of dry matter annually and continues to escalate, posing a substantial economic and e...
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Open AccessR2-ISS staging combined with circulating plasma cells improves risk stratification for newly diagnosed multiple myeloma: a single-center real-world study
We aimed to evaluate if circulating plasma cells (CPC) detected by flow cytometry could add prognostic value of R2-ISS staging. We collected the electronic medical records of 336 newly diagnosed MM patients (N...
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Plasma Ionomic Profile and Interaction Patterns in Coronary Artery Disease Patients
Humans are exposed to various chemical elements that have been associated with the development and progression of diseases such as coronary artery disease (CAD). Unlike previous research, we employed a multi-e...
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Open AccessCorrection: Gut microbiota-derived propionate mediates the neuroprotective effect of osteocalcin in a mouse model of Parkinson’s disease
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From Perspective of Hippocampal Plasticity: Function of Antidepressant Chinese Medicine **aoyaosan
The hippocampus is one of the most commonly studied brain regions in the context of depression. The volume of the hippocampus is significantly reduced in patients with depression, which severely disrupts hippo...
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Article
Influence of pier height on the safety of trains running on high-speed railway bridges during earthquakes
Sudden earthquakes pose a threat to the running safety of trains on high-speed railway bridges, and the stiffness of piers is one of the factors affecting the dynamic response of train-track-bridge system. In ...
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Open AccessTMC6 functions as a GPCR-like receptor to sense noxious heat via Gαq signaling
Thermosensation is vital for the survival, propagation, and adaption of all organisms, but its mechanism is not fully understood yet. Here, we find that TMC6, a membrane protein of unknown function, is highly ...
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A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease
With the implementation of the 11th edition of the International Classification of Diseases (ICD-11) and the publication of the metabolic dysfunction-associated fatty liver disease (MAFLD) nomenclature in 2020...
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Force Property Analysis of a Steel-concrete-steel Bias Component with a Variable Section: The Effect of Design Parameters
In order to study the influence of various design parameters on the ultimate load of the bias component of the pipe-roof pre-construction (PP) structure, a variable section steel-concrete-steel (VSSCS) bias co...
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Anisotropy measurements and characterization of the Qingshankou shale
Qingshankou shale (Gulong area, China) exhibits strong acoustic anisotropy characteristics, posing significant challenges to its exploration and development. In this study, the five full elastic constants and ...
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Article
Triglyceride variability affects diabetic kidney disease in middle-aged and elderly people with type 2 diabetes mellitus in the Guangxi Zhuang population
Dyslipidemia has been implicated in the development and progression of renal disease. To our knowledge, no reports have demonstrated an association between blood lipid level variability and diabetic kidney dis...
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One-step controlled electrodeposition nickel sulfides heterointerfaces favoring the desorption of hydroxyl groups for efficient hydrogen generation
The heterointerface engineering involving different components or phases represents a desirable strategy for enhancing the sluggish kinetics of hydrogen evolution reaction (HER). However, constructing desired ...
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The role of the cGAS-STING signaling pathway in viral infections, inflammatory and autoimmune diseases
Pattern recognition receptors are an essential part of the immune system, which detect pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) and help shape both innate...
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Regulatory effect of Yinchenhao decoction on bile acid metabolism to improve the inflammatory microenvironment of hepatocellular carcinoma in mice
Hepatocellular carcinoma (HCC) is a malignant tumor with extremely high mortality. The tumor microenvironment is the “soil” of its occurrence and development, and the inflammatory microenvironment is an import...
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Low Concentration of Wenyang Tonglin Decoction Promotes Conjugation and Transfer of Drug-Resistant Plasmids among Heterologous Strains
To investigate the effect of low concentration of Wenyang Tonglin Decoction (WTD) on the binding conditions of R45 plasmid conjugative transfer under liquid phase conjugation and its mechanism.
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Associations between whole grains intake and new-onset hypertension: a prospective cohort study
Epidemiological evidences regarding the association between whole grain intake and the risk of new-onset hypertension are still controversial.
